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Catalog | name | Description | price |
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R-C-3119 | Vialinin A CAS:858134-23-3 | Vialinin A is a terphenyl compound originally isolated from the fungi T. terrestris and T.vialis. | price> |
R-R-4789 | Thymidine-15N2 | Thymidine-15N2 is the 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | price> |
R-C-3120 | MSC1094308 CAS:2219320-08-6 | MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase(VCP)/p97 and the type I AAA ATPase VPS4B,with IC50 values of 0.71μM and 7.2μM for VPS4B and p97,respectively. | price> |
R-R-4790 | Mitonafide CAS No.54824-17-8 | Mitonafide (NSC 300288)/CAS No.54824-17-8 is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia. | price> |
R-C-3121 | NMS-859 CAS:1449236-96-7 | NMS-859 is a potent,covalent VCP(p97)inhibitor,with IC50s of 0.37 and 0.36μM for wild-type VCP in the presence of 60μM and 1 mM ATP in cells,respectively. | price> |
R-R-4791 | Werner syndrome RecQ helicase-IN-4 CAS No.2869954-53-8 | Werner syndrome RecQ helicase-IN-4/CAS No.2869954-53-8 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity. | price> |
R-C-3122 | ML241 CAS:1346528-06-0 | ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM. ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. | price> |
R-R-4792 | Cy5-dATP | Cy5-dATP is a Cy5 (HY-D0821)-labeled dATP (HY-136648). Cy5-dATP can be incorporated into a DNA primer. | price> |
R-C-3123 | SR-2211 CAS:1359164-11-6 | SR-2211 selectively binds RORr(Ki=105nM),acting as an inverse agonist of constitutive in vitro RORr activity (IC50=320nM). | price> |
R-R-4793 | Enocitabine CAS No.55726-47-1 | Enocitabine/CAS No.55726-47-1 is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities. | price> |
R-C-3124 | AGN-242428(Vimirogant,VTP-43742) CAS:1802706-04-2 | AGN-242428,also known as VTP-43742,is a potent,selective and orally active RORγt inhibitor for the treatment of autoimmune disorders,including multiple sclerosis and psoriasis. | price> |
R-R-4794 | Deoxythymidine-5-triphosphate-13C10 dilithium | Deoxythymidine-5-triphosphate-13C10 (dTTP-13C10) dilithium is 13C-labeled Deoxythymidine-5-triphosphate (HY-138615). Deoxythymidine-5-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5-triphosphate (dTTP) is used in the synthesis of DNA. | price> |
R-C-3125 | LYC-55716 CAS: 2055536-64-4 | Cintirorgon (LYC-55716)is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells,resulting in enhanced effector function,as well as decreased immunosuppression,resulting in decreased tumor growth,and improved survival. | price> |
R-R-4795 | 5-Propargylamino-ddCTP trisodium | 5-Propargylamino-ddCTP (trisodium), a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis. | price> |
R-C-3126 | AZD-0284 CAS: 2101291-07-8 | AZD-0284 is a potent,selective,inverse agonist of the nuclear receptor RORγ for the potential treatment of Plaque psoriasis. | price> |
R-R-4796 | Spacer phosphoramidite C3 CAS No.110894-23-0 | Spacer phosphoramidite C3/CAS No.110894-23-0 is a phosphorite monomer that can be used in the synthesis of oligonucleotides. | price> |
R-C-3127 | XY101 CAS:2349368-16-5 | XY101 is a potent,selective,metabolically stable and orally available RORγ inverse agonist with an IC50 of 30nM and a Kd of 380nM. | price> |
R-R-4797 | guanosine-5-triphosphate-5-adenosine-triammonium | Guanosine 5-triphosphate-5-adenosine (GpppA) triammonium, a 5 cap analog, can be used for RNA synthesis in vitro. Guanosine 5-triphosphate-5-adenosine triammonium is a fluorescent substrate analog. | price> |
R-C-3128 | S18-000003 CAS:2068119-11-7 | S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t(RORγt)inhibitor with an IC50 of 29nM.S18-000003 inhibits IL-17 production. | price> |
R-R-4798 | Datelliptium chloride CAS No.105118-14-7 | Datelliptium chloride/CAS No.105118-14-7 is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities. | price> |