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Catalog	name	Description	price
R-R-4767	DNA31 CAS No.845626-57-5	DNA31/CAS No.845626-57-5 is a potent RNA polymerase inhibitor.	price>
R-C-3098	Aftin-4 CAS# 866893-90-5	Aftin-4 is an amyloid-β42 inducer that electively and potently increases production of extracellular Aβ42 and decreases production of extracellular Aβ38 in cultured cells.	price>
R-R-4768	ZIM CAS No.301298-87-3	ZIM/CAS No.301298-87-3, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research.	price>
R-R-4769	WRN inhibitor 3 CAS No.2923009-48-5	WRN inhibitor 3 (example 110)/CAS No.2923009-48-5, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer.	price>
R-R-4770	5-Methylcytosine-d4 CAS No.1219795-15-9	5-Methylcytosine-d4/CAS No.1219795-15-9 is the deuterium labeled 5-Methylcytosine. 5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development.	price>
R-C-3101	TAK-981 CAS:1858276-04-6	TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.	price>
R-R-4771	BVDV-IN-1 CAS No.345651-04-9	BVDV-IN-1/CAS No.345651-04-9 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).	price>
R-C-3102	N106 CAS:862974-25-2	N106,activator of SUMO-activating enzyme,E1 ligase.Increases SERCA2a SUMOylation and activity,and enhances contractility in rat cardiomyocytes in vitro.	price>
R-R-4772	Remdesivir nucleoside monophosphate CAS No.1911578-74-9	Remdesivir nucleoside monophosphate/CAS No.1911578-74-9 is a metabolite of Remdesivir. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV.	price>
R-C-3103	COH000 CAS:1534358-79-6	COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.	price>
R-R-4773	Thiarabine CAS No.26599-17-7	Thiarabine (OSI-7836)/CAS No.26599-17-7 shows potent anti-tumor activity and inhibition of DNA synthesis.	price>
R-C-3104	PYR-41 CAS:418805-02-4	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.PYR-41 induce apoptosis.	price>
R-R-4774	Holomycin CAS No.488-04-0	Holomycin/CAS No.488-04-0 is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis.	price>
R-C-3105	BAY 11-7082 (BAY 11-7821) CAS:19542-67-7	BAY 11-7082(BAY 11-7821)is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM,respectively.BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.	price>
R-R-4775	2-Deoxyadenosine 5-di-phos-phate disodium CAS No.72003-83-9	2-Deoxyadenosine 5-di-phos-phate disodium (dADP disodium)/CAS No.72003-83-9 is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes.	price>
R-C-3106	TZ9 CAS:1002789-86-7	TZ9 is a novel inhibitor of Rad6 ubiquitin conjugating enzyme(E2 enzyme); inhibits MDA-MB-231 cell proliferation with IC50 of ~6 uM.	price>
R-R-4776	Capecitabine-d11 CAS No.1132662-08-8	Capecitabine-d11/CAS No.1132662-08-8 is the deuterium labeled Capecitabine. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.	price>
R-C-3107	HLI-98C CAS:317326-90-2	HLI-98C,an analog,indeed inhibited Mdm2 E3 ligase activity.	price>
R-R-4777	N6-Methyl-dA phosphoramidite CAS No.105931-58-6	N6-Methyl-dA phosphoramidite/CAS No.105931-58-6 can be used in the synthesis of oligodeoxyribonucleotides.	price>
R-C-3108	TAME CAS:901-47-3	TAME is a small molecule anaphase-promoting complex/cyclosome(APC)inhibitor with an IC50 of 12μM.	price>

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