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Catalog	name	Description	price
R-R-4831	Proguanil-d6 hydrochloride	Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.	price>
R-C-3162	Epristeride CAS:119169-78-7	Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2.	price>
R-R-4832	Viltolarsen sodium	Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research.	price>
R-C-3163	AR-231453 CAS:733750-99-7	AR-231453 is a potent and selective small molecule agonis of GPR119 that enhances glucose dependent insulin secretion and glucagon like peptide-1 (GLP-1) release.	price>
R-R-4833	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite CAS No.143774-48-5	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite (compound 1B)/CAS No.143774-48-5 is a phosphoramidite of 5-Fluoro-2-deoxycytidine.	price>
R-C-3164	6-OAU CAS:83797-69-7	6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay.6-OAU(GTPL5846,6-n-octylaminouracil)increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512nM.	price>
R-R-4834	Trifluridine/tipiracil hydrochloride mixture CAS No.733030-01-8	Trifluridine/tipiracil hydrochloride mixture (TAS-102)/CAS No.733030-01-8 is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA.	price>
R-C-3165	Versipelostatin	Versipelostatin is a novel GRP78/Bip molecular chaperone down-regulator of microbial origin that was isolated from the metabolite of Streptomyces versipellis strain 4083-SVS6.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4835	2-Chloroadenosine CAS No.146-77-0	2-Chloroadenosine/CAS No.146-77-0, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent Ki=33 μM) and high-affinity nitrobenzylthioinosine binding (apparent Ki=0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes.	price>
R-R-4836	7-Methylguanosine CAS No.20244-86-4	7-Methylguanosine/CAS No.20244-86-4 is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 µM.	price>
R-C-3167	NCRW0005-F05 CAS:342779-66-2	NCRW0005-F05, first antagonist selective for GPR139 (IC50 value 0.21 uM); a useful tool to study GPR139 pharmacology, especially in combination with the GPR139 agonist JNJ 63533054.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4837	Sangivamycin CAS No.18417-89-5	Sangivamycin (NSC 65346)/CAS No.18417-89-5, a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers.	price>
R-C-3168	BMS-564929 CAS:627530-84-1	BMS-564929 is a novel, highly potent, orally active, nonsteroidal tissue selective androgen receptor (AR) modulator, and this compound has been advanced to clinical trials for the treatment of age-related functional decline. Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4838	3-Methylcytidine CAS No.2140-64-9	3-Methylcytidine/CAS No.2140-64-9, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.	price>
R-C-3169	AZD3514 CAS:1240299-33-5	AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2M and has ability of reducing AR protein expression.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4839	6-Thioinosine CAS No.574-25-4	6-Thioinosine (6TI)/CAS No.574-25-4 is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα.	price>
R-C-3170	GSK-2881078 CAS :1539314-06-1	GSK 2881078 is a nonsteroidal selective modulator of androgen receptor that is potentially used for the treatment of cachexia.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4840	N2-Methylguanosine CAS No.2140-77-4	N2-methylguanosine/CAS No.2140-77-4 is a modified nucleoside that occurs at several specific locations in many tRNAs.	price>
R-C-3171	MK-0773 CAS: 606101-58-0	MK-0773,one of selective androgen receptor modulators(SARMs),is a 4-aza-steroid that exhibited tissue selectivity in humans (IC50=6.6nM).Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4841	3-Deazauridine CAS No.23205-42-7	3-Deazauridine (NSC 126849)/CAS No.23205-42-7 is a uridine analogue. 3-Deazauridine competitively inhibits cytidine triphosphate synthase to inhibit the biosynthesis of cytidine-5-triphosphate. 3-Deazauridine acts synergistically with several antineoplastic agents, acting as a biological response modifier.	price>

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