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Catalog | name | Description | price |
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R-R-4821 | Trimetrexate glucuronate CAS No.82952-64-5 | Trimetrexate glucuronate (NSC 352122)/CAS No.82952-64-5 is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia. | price> |
R-C-3152 | Moxonidine CAS:75438-57-2 | Moxonidine(BDF5895) is a selective agonist at the imidazoline receptor subtype 1. | price> |
R-R-4822 | Trimethoprim-d9 CAS No.1189460-62-5 | Trimethoprim-d9/CAS No.1189460-62-5 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment. | price> |
R-C-3153 | Imidapril (Tanatril) CAS:89371-37-9 | Imidapril(Tanatril)is an inhibitor of angiotensin converting enzyme(ACE). | price> |
R-R-4823 | Tetroxoprim CAS No.53808-87-0 | Tetroxoprim/CAS No.53808-87-0 is an antimicrobial DHFR inhibitor. | price> |
R-C-3154 | Telmisartan CAS:144701-48-4 | Telmisartan is an angiotensin II receptor antagonist that inhibits the angiotensin II AT1 receptor. | price> |
R-R-4824 | Pyrimethamine-d3 CAS No.1189936-99-9 | Pyrimethamine-d3/CAS No.1189936-99-9 is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR). | price> |
R-C-3155 | Fimasartan CAS :247257-48-3 | Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. | price> |
R-R-4825 | Aditoprime CAS No.56066-63-8 | Aditoprime (Aditoprim)/CAS No.56066-63-8, a selective bacterial dihydrofolate reductase (DHFR) inhibitor, inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime inhibits E.coli and L.casei DHFR with IC50 of 47 and 520 nM, respectively. Aditoprime has a broad antimicrobial spectrum, good antibacterial activity and excellent pharmacokinetics. | price> |
R-C-3156 | Zofenopril CAS:81872-10-8 | Zofenopril is an angiotensin-converting enzyme(ACE)inhibitor with an IC50 of 81μM. | price> |
R-R-4826 | LY309887 CAS No.127228-54-0 | LY309887/CAS No.127228-54-0 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity. | price> |
R-C-3157 | SL910102 CAS:144756-71-8 | SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. | price> |
R-R-4827 | Calcium N5-methyltetrahydrofolate CAS No.26560-38-3 | Calcium N5-methyltetrahydrofolate(NSC173328)/CAS No.26560-38-3 is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. | price> |
R-C-3158 | Sparsentan CAS:254740-64-2 | Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM,respectively. | price> |
R-R-4828 | Fanotaprim CAS No.2120282-75-7 | Fanotaprim/CAS No.2120282-75-7 is a dihydrofolate reductase (DHFR) inhibitor with IC50s of 1.57 and 308 nM for tgDHFR (Toxoplasma gondii DHFR) and hDHFR (human DHFR), respectively. Fanotaprim has the potential for the research of toxoplasmosis. | price> |
R-C-3159 | CGP-42112 CAS:127060-75-7 | CGP-42112(CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist. | price> |
R-R-4829 | Cycloguanil-d6 | Cycloguanil-d66 is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor. | price> |
R-C-3160 | AVE 0991 CAS:304462-19-9 | AVE 0991 is a nonpeptide and orally active angiotensin-(1-7)receptor agonist with an IC50 of 21nM. | price> |
R-R-4830 | Trimethoprim-d3 CAS No.1189923-38-3 | Trimethoprim-d3/CAS No.1189923-38-3 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment. | price> |
R-C-3161 | SR-12813 CAS:126411-39-0 | SR-12813 is a pregnane X receptor(PXR)agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM. | price> |