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Catalog	name	Description	price
R-R-4635	R-1479 CAS No.478182-28-4	R-1479/CAS No.478182-28-4, a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.	price>
R-C-2966	Etoricoxib CAS：202409-33-4	Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.	price>
R-R-4636	Werner syndrome RecQ helicase-IN-3 CAS No.2869954-98-1	Werner syndrome RecQ helicase-IN-3/CAS No.2869954-98-1 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity.	price>
R-C-2967	Olcegepant CAS：204697-65-4	Olcegepant also known as BIBN-4096 or BIBN-4096BS is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1)receptor.	price>
R-R-4637	Hycanthone CAS No.3105-97-3	Hycanthone/CAS No.3105-97-3 is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.	price>
R-C-2968	SB271046 CAS：209481-20-9	SB271046 is a potent,selective and orally active 5-HT6 receptor antagonist with pKi of 8.9,exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.	price>
R-R-4638	Branaplam hydrochloride CAS No.1562338-39-9	Branaplam (LMI070; NVS-SM1) hydrochloride/CAS No.1562338-39-9 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model	price>
R-C-2969	SB269652 CAS：215802-15-6	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor(D2R).SB269652 binds in a bitopic manner at one protomer of a D2R dimer and modulates the binding of dopamine at a second protomer.	price>
R-R-4639	Galidesivir CAS No.249503-25-1	Galidesivir (BCX4430)/CAS No.249503-25-1, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.	price>
R-C-2970	SB-277011 CAS：215803-78-4	SB-277011 is a drug which acts as a potent and selective dopamine D3 receptor antagonist which is around 80-100x selective for D3 over D2 and lacks any partial agonist activity.	price>
R-R-4640	Gemifloxacin mesylate CAS No.210353-53-0	Gemifloxacin mesylate (SB-265805S; LB-20304a)/CAS No.210353-53-0 is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.	price>
R-C-2971	Lumiracoxib CAS:220991-20-8	Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Only for scientific research, not for human body.	price>
R-R-4641	AG-636 CAS No.1623416-31-8	AG-636/CAS No.1623416-31-8 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. AG-636 has strong anticancer effects.	price>
R-R-4642	BCH001 CAS No.384859-58-9	BCH001/CAS No.384859-58-9, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging.	price>
R-C-2973	Adoprazine (SLV313) CAS:222551-17-9	Adoprazine,also known as SLV313,is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug. Adoprazine is part of the Antidepressant Agent group.Only for scientific research, not for human body.	price>
R-R-4643	Braco-19 CAS No.351351-75-2	Braco-19/CAS No.351351-75-2 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-C-2974	NPS 2390 CAS:226878-01-9	NPS2390 is a group I mGlu antagonist. It displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket.Only for scientific research, not for human body.	price>
R-R-4644	Dithranol CAS No.1143-38-0	Dithranol (Anthralin)/CAS No.1143-38-0 is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair.	price>
R-C-2975	Lofepramine CAS# 23047-25-8	Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535).Only for scientific research, not for human body.	price>
R-R-4645	Ethynylcytidine CAS No.180300-43-0	Ethynylcytidine (ECyD)/CAS No.180300-43-0, a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>

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