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Catalog	name	Description	price
R-R-4737	HBV-IN-4 CAS No.2305897-84-9	HBV-IN-4/CAS No.2305897-84-9, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 induces the formation of genome-free capsids and has potent anti-HBV potencies.	price>
R-C-3068	BI-D1870 CAS:501437-28-1	BI-D1870 is a potent and specific inhibitor of the p90 ribosomal S6 kinase (RSK) isoforms in vitro and in vivo, which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 10–30 nM.Only for scientific research, not for human body.	price>
R-R-4738	Sodium Camptothecin CAS No.25387-67-1	Sodium Camptothecin/CAS No.25387-67-1 is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.	price>
R-C-3069	IM156 CAS: 1422365-93-2	IM156 (HL156A), a metformin derivative, is a potent activator of AMPK that increases AMPK phosphorylation. IM156 blocks oxidative phosphorylation (OXPHOS) through the inhibition of complex I and increases apoptosis. IM156 ameliorates various types of fibrosis and inhibits tumors.Only for scientific research, not for human body.	price>
R-R-4739	2-(Methylamino)-1H-purin-6(7H)-one CAS No.10030-78-1	2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine)/CAS No.10030-78-1 is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.	price>
R-C-3070	MK-3903 CAS：1219737-12-8	MK-3903 is a potent and selective AMPK activator with an EC50 of 8 nM for α1 β1 γ1 subunit. It activates 10 of the 12 pAMPK complexes with EC50 values in the range of 8-40 nM and maximal activation >50%.Only for scientific research, not for human body.	price>
R-R-4740	Thymidine-d4 CAS No.347841-67-2	Thymidine-d4/CAS No.347841-67-2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.	price>
R-C-3071	PF-06409577 CAS:1467057-23-3	PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.Only for scientific research, not for human body.	price>
R-R-4741	Sterigmatocystine CAS No.10048-13-2	Sterigmatocystine/CAS No.10048-13-2 is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.	price>
R-C-3072	OTSSP167 CAS:1431697-89-0	OTSSP167 (OTS167) is a highly potent MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.Only for scientific research, not for human body.	price>
R-R-4742	DHPS-IN-1 CAS No.2643300-54-1	DHPS-IN-1/CAS No.2643300-54-1, with the best DHPS inhibitory potency (IC50 = 0.014 μM), exhibits excellent inhibition against melanoma cells.	price>
R-C-3073	YU238259 CAS:1943733-16-1	YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.Only for scientific research, not for human body.	price>
R-R-4743	Filibuvir CAS No.877130-28-4	Filibuvir/CAS No.877130-28-4 is an orally active, selective non-nucleoside inhibitor of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase (RdRp). Filibuvir binds noncovalently in the thumb II allosteric pocket of NS5B. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM for both isoforms, respectively. Filibuvir preferentially inhibits elongative RNA synthesis and potently decreases viral RNA accumulation.	price>
R-C-3074	LTURM34 CAS:1879887-96-3	LTURM34 is a specific DNA-PK inhibitor, 170-fold more selective for DNA-PK activity compared to PI3K activity, with IC50 value of 0.034 μM.Only for scientific research, not for human body.	price>
R-R-4744	SMN-C2 CAS No.1446311-56-3	SMN-C2/CAS No.1446311-56-3, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research.	price>
R-C-3075	KU-0060648 CAS:881375-00-4	KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM. Only for scientific research, not for human body.	price>
R-R-4745	Laflunimus CAS No.147076-36-6	Laflunimus (HR325)/CAS No.147076-36-6 is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor.	price>
R-C-3076	SU 5205 CAS:3476-86-6	SU5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 9.6 µM.Only for scientific research, not for human body.	price>
R-R-4746	Adenine-d CAS No.109923-52-6	Adenine-d/CAS No.109923-52-6 is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.	price>
R-C-3077	SU-5408 CAS:15966-93-5	SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and selective inhibitor of VEGFR2 Kinase with IC50 of 70 nM.Only for scientific research, not for human body.	price>

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