Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-4811	Alvespimycin hydrochloride CAS No.467214-21-7	Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476)/CAS No.467214-21-7 is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.	price>
R-C-3142	AZD2906 CAS:1034148-15-6	AZD2906 is a selective glucocorticoid receptor(GR)agonist,increases micronucleated immature erythrocytes in the bone marrow of rats.AZD2906 shows IC50s of 2.2,0.3, 41.6 and 7.5nM at GR in human,rat PBMC and human,rat whole blood,respectively. Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4812	NTPAN-MI CAS No.2411398-95-1	NTPAN-MI/CAS No.2411398-95-1 is a fluorescent probe. NTPAN-MI is selectively activated upon labeling unfolded proteins with exposed thiols, thereby reporting on the extent of proteostasis.	price>
R-C-3143	Fosdagrocorat CAS:1044535-58-1	Fosdagrocorat(PF-04171327)is a dissociated glucocorticoid receptor agonist.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4813	MitoSOX Red CAS No.1003197-00-9	MitoSOX Red/CAS No.1003197-00-9 is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.	price>
R-C-3144	Mapracorat CAS:887375-26-0	Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4814	Folinic acid CAS No.58-05-9	Folinic acid (Leucovorin)/CAS No.58-05-9 is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.	price>
R-C-3145	Anastrozole CAS:120511-73-1	Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor.It may offer greater selectivity compared with other aromatase inhibitors,being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.Our products are only suitable for scientific research experiments,not for clinical experiments and human body.	price>
R-R-4815	Proguanil CAS No.500-92-5	Proguanil/CAS No.500-92-5, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor.	price>
R-C-3146	Candesartan (Atacand) CAS:139481-59-7	Candesartan is an angiotensin receptor blocker(also called an angiotensin-II receptor antagonist or an AIIRA).Our products are only suitable for scientific research experiments,not for clinical experiments and human body.	price>
R-R-4816	Aminopterin CAS No.54-62-6	Aminopterin (4-Aminofolic acid)/CAS No.54-62-6, the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia.	price>
R-C-3147	Clinofibrate (S-8527) CAS:30299-08-2	Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4817	Metoprine CAS No.7761-45-7	Metoprine (BW 197U)/CAS No.7761-45-7 is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent.	price>
R-C-3148	Rosuvastatin CAS:287714-41-4	Rosuvastatin is a member of the drug class of statins,used to treat high cholesterol and related conditions, and to prevent cardiovascular disease.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4818	LSN 3213128 CAS No.1941211-99-9	LSN 3213128/CAS No.1941211-99-9 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.	price>
R-C-3149	Aliskiren (CGP 60536) CAS:173334-57-1	Aliskiren(CGP 60536) is a direct renin inhibitor with IC50 of 1.5nM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4819	Pelitrexol CAS No.446022-33-9	Pelitrexol (AG 2037)/CAS No.446022-33-9 is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice.	price>
R-C-3150	MLN-4760 CAS:305335-31-3	MLN-4760(compound 16)is a potent and selective inhibitor of human angiotensin-converting enzyme 2(ACE2)with IC50 of 0.44nM.MLN-4760 also inhibits bovine carboxypeptidase A(CPDA)with IC50 of 27μM.Our products are only suitable for scientific research experiments,not for clinical experiments and human body.	price>
R-R-4820	Methotrexate metabolite CAS No.19741-14-1	Methotrexate metabolite (DAMPA)/CAS No.19741-14-1, the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent. Methotrexate metabolite is an antimalarial agent, which inhibits the parasite growth with an IC50 of 446 nM against the antifolate-sensitive strain and 812 nM against the highly resistant strain under physiological folate conditions. Methotrexate metabolite is inactive against mammalian cells. Methotrexate metabolite is a minimal inhibitor of dihydrofolate reductase among metabolites of methotrexate .	price>
R-C-3151	Eprosartan CAS:133040-01-4	Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure.	price>

678679680681682683 684685686687688