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R-C-2970 SB-277011 CAS:215803-78-4 SB-277011 is a drug which acts as a potent and selective dopamine D3 receptor antagonist which is around 80-100x selective for D3 over D2 and lacks any partial agonist activity. price>
R-R-4640 Gemifloxacin mesylate CAS No.210353-53-0 Gemifloxacin mesylate (SB-265805S; LB-20304a)/CAS No.210353-53-0 is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections. price>
R-C-2971 Lumiracoxib CAS:220991-20-8 Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Only for scientific research, not for human body. price>
R-R-4641 AG-636 CAS No.1623416-31-8 AG-636/CAS No.1623416-31-8 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. AG-636 has strong anticancer effects. price>
R-R-4642 BCH001 CAS No.384859-58-9 BCH001/CAS No.384859-58-9, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging. price>
R-C-2973 Adoprazine (SLV313) CAS:222551-17-9 Adoprazine,also known as SLV313,is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug. Adoprazine is part of the Antidepressant Agent group.Only for scientific research, not for human body. price>
R-R-4643 Braco-19 CAS No.351351-75-2 Braco-19/CAS No.351351-75-2 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor. price>
R-C-2974 NPS 2390 CAS:226878-01-9 NPS2390 is a group I mGlu antagonist. It displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket.Only for scientific research, not for human body. price>
R-R-4644 Dithranol CAS No.1143-38-0 Dithranol (Anthralin)/CAS No.1143-38-0 is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair. price>
R-C-2975 Lofepramine CAS# 23047-25-8 Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535).Only for scientific research, not for human body. price>
R-R-4645 Ethynylcytidine CAS No.180300-43-0 Ethynylcytidine (ECyD)/CAS No.180300-43-0, a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-2976 PD 102807 CAS:23062-91-1 PD 102807 is an m4 muscarinic receptor antagonist with an IC50 of 90.7 nm.PD 102807 inhibited M1,M2,m3 and M5 muscarinic receptors with IC50 of 6558.7,3440.7,950.0 and 7411.7nm, respectively. It has the effect of anti dyskinesia.Only for scientific research, not for human body. price>
R-R-4646 TTP-8307 CAS No.950225-08-8 TTP-8307/CAS No.950225-08-8 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP). price>
R-C-2977 Bay 36-7620 CAS:232605-26-4 Selective mGlu1 receptor non-competitive antagonist (IC50 = 0.16 μM) with inverse agonist activity. Impairs classical conditioning and associated synaptic plasticity in hippocampal neurons. Exhibits neuroprotective and anticonvulsive effects in vivo following systemic administration.Only for scientific research, not for human body. price>
R-R-4647 Neobavaisoflavone CAS No.41060-15-5 Neobavaisoflavone/CAS No.41060-15-5, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation. price>
R-R-4648 BRD32048 CAS No.433694-46-3 BRD32048/CAS No.433694-46-3 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen. price>
R-R-4649 Cinoxacin CAS No.28657-80-9 Cinoxacin (Compound 64716)/CAS No.28657-80-9, a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis. price>
R-R-4650 Deoxyguanosine triphosphate trisodium salt CAS No.93919-41-6 Deoxyguanosine triphosphate (dGTP) trisodium salt/CAS No.93919-41-6 is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. price>
R-R-4651 Braco-19 trihydrochloride CAS No.1177798-88-7 Braco-19 trihydrochloride/CAS No.1177798-88-7 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor. price>
R-R-4652 NVS-SM2 CAS No.1562333-92-9 NVS-SM2/CAS No.1562333-92-9 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research. price>