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Catalog	name	Description	price
R-R-4720	RNase L-IN-1	RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation.	price>
R-C-3051	WYE-125132 (WYE-132) CAS:1144068-46-1	WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).	price>
R-R-4721	Cytarabine triphosphate trisodium CAS No.1179343-17-9	Cytarabine triphosphate (Ara-CTP) trisodiu/CAS No.1179343-17-9, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine.	price>
R-C-3052	INK 128 (MLN0128) CAS:1224844-38-5	INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.	price>
R-R-4722	1,1,1-Trifluoroethyl-PEG4-azide CAS: 1817735-35-5	1,1,1-Trifluoroethyl-PEG4-azide/CAS: 1817735-35-5 is a crosslinker containing an azide group and a trifluoroethyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.	price>
R-C-3053	GDC-0349 CAS:1207360-89-1	GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases.	price>
R-R-4723	1,1,1-Trifluoroethyl-PEG5-Propargyl CAS: 1817735-37-7	1,1,1-Trifluoroethyl-PEG5-Propargyl/CAS: 1817735-37-7 forms triazole linkage with azides via copper catalyzed azide-alkyne Click Chemistry. The trifluoroethyl group is reactive towards primary amine groups in proteins, antibody and other molecules and surfaces.	price>
R-C-3054	WAY-600 CAS:1062159-35-6	WAY-600 is a single digit nanomolar inhibitor of the mTOR kinases, with significant selectivity for these enzymes over phosphatidylinositol 3-kinase (PI3K) isofoms (>100-fold).	price>
R-R-4724	1,1,1-Trifluoroethyl-PEG2-azide CAS: 1835759-68-6	1,1,1-Trifluoroethyl-PEG2-azide/CAS: 1835759-68-6 is a crosslinker containing an azide group and a trifluroethyl group. The azide group can participate in Click Chemistry reactions with reagents such as alkynes, DBCO and BCN. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.	price>
R-C-3055	WYE-687 CAS: 1062161-90-3	WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).	price>
R-R-4725	1,1,1-Trifluoroethyl-PEG4-aminooxy CAS: 1895922-78-7	1,1,1-Trifluoroethyl-PEG4-aminooxy/CAS: 1895922-78-7 is a fluorine containing PEG molecule. The aminooxy group can be used in bioconjugation and It reacts with an aldehyde to form an oxime bond.	price>
R-C-3056	WYE-354 CAS:1062169-56-5	WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).	price>
R-R-4726	Octakis-(6-bromo-6-deoxy)-y-cyclodextrin CAS No.53784-84-2	Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin/CAS No.53784-84-2 is a perbrominated γ-cyclodextrin at the primary side. Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is also a commonly used intermediate in the modification of cyclodextrin.	price>
R-C-3057	Ridaforolimus (Deforolimus, MK-8669) CAS:572924-54-0	Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line.	price>
R-R-4727	Heptakis(2,3,6-tri-O-benzoyl)-b-cyclodextrin CAS No.23666-43-5	Heptakis(2,3,6-tri-O-benzoyl)-β-cyclodextrin/CAS No.23666-43-5 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.	price>
R-C-3058	Paeoniflorin (NSC 178886) CAS:23180-57-6	Paeoniflorin (NSC 178886) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.	price>
R-R-4728	Mono-2-O-(p-toluenesulfonyl)-a-cyclodextrin CAS No.93184-10-2	Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin/Mono-2-o-(p-toluenesulfonyl)-alpha-cyclodextrin/CAS No.93184-10-2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.	price>
R-C-3059	HUN86320 CAS:882286-32-0	TSPC is an inhibitor for GA perception by in vitro and in planta evaluations.	price>
R-R-4729	Mono-2-O-(p-toluenesulfonyl)-y-cyclodextrin CAS No.97227-32-2	Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin/Mono-2-O-(p-toluenesulfonyl)-gamma-cyclodextrin/CAS No.97227-32-2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.	price>
R-C-3060	BRD3731 cas:2056262-07-6	BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. BRD3731 inhibits the phosphorylation of CRMP2 in SH-SY5Y cells. BRD3731 decreases β-catenin S33/37/T41 phosphorylation and induces β-catenin S675 phosphorylation in HL-60 cells. BRD3731 impairs colony formation in TF-1 and increases colony forming ability in the MV4-11 cell line.	price>

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