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Catalog	name	Description	price
R-C-3016	NU7441 (KU-57788) CAS：503468-95-9	NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 μM and 5 μM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.Only for scientific research, not for human body.	price>
R-R-4686	AV-153 free base CAS No.19350-66-4	AV-153 free base/CAS No.19350-66-4, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity.	price>
R-C-3017	SB269970 HCl CAS：261901-57-9	SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors.Only for scientific research, not for human body.	price>
R-R-4687	DTP3 TFA CAS No.2759216-46-9	DTP3 TFA/CAS No.2759216-46-9 is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway.	price>
R-R-4688	H3B-968 CAS No.2912294-90-5	H3B-968/CAS No.2912294-90-5 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM)，which acts function as helicase，ATPase，and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However，H3B-968 inhibits WRN helicase activity，competitively with ATP.	price>
R-R-4689	Pseudouridimycin CAS No.1566586-52-4	Pseudouridimycin (PUM)/CAS No.1566586-52-4, an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria.	price>
R-R-4690	6-Hydroxy-DOPA CAS No.21373-30-8	6-Hydroxy-DOPA/CAS No.21373-30-8 is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer.	price>
R-R-4691	5-Propargylamino-dCTP CAS No.115899-39-3	5-Propargylamino-dCTP/CAS No.115899-39-3 is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4692	(2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate CAS :864163-80-4	(2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate/CAS :864163-80-4 is a coordination complex featuring an iridium(III) ion at its core. The complex is comprised of 2,2-bipyridine ligands and two 2-(2,4-difluorophenyl)pyridine ligands that coordinate with the iridium ion. The hexafluorophosphate anion (PF₆⁻) is included in the compound to balance the charge of the iridium center.This complex is known for its luminescent properties and finds applications in fields such as organic light-emitting diodes (OLEDs), where the unique photophysical characteristics of the iridium center play a crucial role in light emission processes. The presence of the difluorophenyl groups in the ligands can influence the complex emission wavelengths and efficiency, contributing to its potential in optoelectronic devices.The combination of the bipyridine and difluorophenylpyridine ligands around the iridium ion results in a specific coordination environment that influences the complex stability, reactivity, and optical properties.	price>
R-R-4693	Ir(p-CF3-ppy)3 CAS No:500295-52-3	Ir(p-CF3-ppy)3/CAS No:500295-52-3 is a new type of organometallic compound. It has been shown to be useful for the formation of bioactive molecules, such as linear and hydrogenated aromatic compounds, thioethers, and chlorinated bonds. This compound can also catalyze bond formations, radical reactions, and fluorination reactions. Ir(p-CF3-ppy)3 has also been studied as a photocatalyst in the functionalization of organic molecules.	price>
R-R-4694	tert-Butyl ((1R,2R)-2-amino-3,3-difluorocyclohexyl)carbamate CAS No:1109284-37-8	tert-Butyl ((1R,2R)-2-amino-3,3-difluorocyclohexyl)carbamate/CAS No:1109284-37-8 is a chemical compound. This chemical compound may have applications in organic synthesis, medicinal chemistry, or as a building block for more complex molecules. The presence of the difluorocyclohexyl group and the carbamate functionality imparts specific properties to the compound which can be utilized in various chemical processes or as a structural component in the synthesis of bioactive compounds.	price>
R-C-3025	PF-4989216 CAS：1276553-09-3	PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Only for scientific research, not for human body.	price>
R-R-4695	Biotin-TEG-NH2 TFA CAS No:1334172-59-6	Biotin-TEG-NH2 TFA/N-Biotin-tetra(ethylene glycol)-diamine trifluoroacetate/CAS No:1334172-59-6 is a chemical compound that consists of biotin (a vitamin B7 derivative) linked to an amino group (NH2) through a TEG (triethylene glycol) spacer, with a trifluoroacetic acid (TFA) counterion. Biotin-TEG-NH2 TFA is a versatile compound used in biochemistry, molecular biology, and biotechnology for applications such as protein labeling, protein detection, and immunoassays due to its biotin-streptavidin interaction and its potential for functionalization through the amino group.	price>
R-C-3026	AZD8835 cas:1620576-64-8	AZD8835 is a potent inhibitor of PI3Kα (wild type, E545K and H1047R mutations) and PI3Kδ with excellent selectivity vs. PI3Kβ, PI3Kγ and an excellent general kinase selectivity.Only for scientific research, not for human body.	price>
R-R-4696	Bis-dPEG5-PFP ester CAS No:1334177-78-4	Bis-dPEG5-PFP ester/Bis(perfluorophenyl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate/CAS No:1334177-78-4 is a halogenated PEG (polyethylene glycol) compound that is used in various applications. It is a homobifunctional PEG with two fluorinated phenyl groups attached to the PEG backbone. This unique structure provides enhanced stability and hydrophobicity, making it ideal for use in drug delivery systems, surface modifications, and bioconjugation reactions. The fluorophenyl groups of Bis-dPEG5-PFP ester offer excellent reactivity towards nucleophiles, allowing for efficient conjugation with biomolecules such as proteins, peptides, and antibodies. Its high purity and low polydispersity ensure consistent results in each application. With its fluorine-containing moieties, Bis-dPEG5-PFP ester can also be utilized as a labeling agent for imaging purposes. The presence of fluorine atoms enables easy detection and tracking of labeled compounds using techniques like fluorine-19 magnetic resonance imaging (19F MRI).	price>
R-C-3027	TGR-1202 (Umbralisib) CAS:1532533-67-7	Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.Only for scientific research, not for human body.	price>
R-R-4697	6-Fluoro-6-deoxy-D-galactose CAS No:4536-07-6	6-Fluoro-6-deoxy-D-galactose (FDG)/CAS No:4536-07-6 is a fluorinated sugar. FDG has been shown to inhibit the uptake of glucose by l1210 murine cells, as well as the transport of glucose into the cell. It also inhibited cell culture and enzyme activities in human liver tissue. The electron microscopic analysis of cytochalasin B and trifluoroacetic acid treated cells showed that FDG disrupts the microtubule network, leading to inhibition of cellular proliferation. FDG has also been found to inhibit the synthesis of DNA and RNA in L5178 murine lymphoma cells.	price>
R-C-3028	GDC-0326 CAS:1282514-88-8	GDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.Only for scientific research, not for human body.	price>
R-R-4698	1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose CAS No:444586-86-1	1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose/CAS No:444586-86-1 is a sugar that is modified with fluorine. It has been synthesized using the "click" reaction methodology and is available for custom synthesis. This synthetic sugar can be used in glycosylation reactions or as a monosaccharide or polysaccharide in complex carbohydrate click chemistry. This product is of high purity and can be modified with methyl groups or other functional groups to suit your needs.	price>
R-C-3029	acalisib (GS-9820) CAS:870281-34-8	Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.Only for scientific research, not for human body.	price>

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