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Catalog	name	Description	price
R-C-2960	DSPE-TK-PEOz	DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification. At present, the mainly include synthetic phospholipids, PEG derivatives, block copolymers, gold nanoparticles, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click chemistry and macrocyclic ligands.	price>
R-R-4630	Lapachol CAS No.84-79-7	Lapachol/CAS No.84-79-7, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity.	price>
R-C-2961	5-(4-hydroxyphenyl)-10,15,20-(4-methylphenyl) porphine	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme). These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable	price>
R-R-4631	DHX9-IN-1 CAS No.2973747-89-4	DHX9-IN-1 (example 160)/CAS No.2973747-89-4 is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the IC50 of 9.45 nM that has antitumor activity.	price>
R-C-2962	Mp-a08 CAS：219832-49-2	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings.It is changed from animal and plant pigments (chlorophyll or heme).These pigments contain pyrrole nuclei.It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable.	price>
R-R-4632	Dasabuvir CAS No.1132935-63-7	Dasabuvir (ABT-333)/CAS No.1132935-63-7 is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively.	price>
R-C-2963	5,10,15,20-Tetrakis(3,5-dihydroxyphenyl)porphyrin cas 145764-54-1	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme).These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable4634.	price>
R-R-4633	Pyrazofurin CAS No.30868-30-5	Pyrazofurin/CAS No.30868-30-5, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5-phosphate (UMP) synthase. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 µM in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C.	price>
R-C-2964	5,10,15,20-Tetrakis(3,5-dimethoxyphenyl )-21H,23H-porphyrin Cas:74684-34-7	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme). These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable.	price>
R-R-4634	ccc_R08 CAS No.2919019-72-8	ccc_R08/CAS No.2919019-72-8 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection.	price>
R-C-2965	SB-269970	SB269970 is a potent and selective 5-HT7 receptor antagonist.	price>
R-R-4635	R-1479 CAS No.478182-28-4	R-1479/CAS No.478182-28-4, a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.	price>
R-C-2966	Etoricoxib CAS：202409-33-4	Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.	price>
R-R-4636	Werner syndrome RecQ helicase-IN-3 CAS No.2869954-98-1	Werner syndrome RecQ helicase-IN-3/CAS No.2869954-98-1 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity.	price>
R-C-2967	Olcegepant CAS：204697-65-4	Olcegepant also known as BIBN-4096 or BIBN-4096BS is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1)receptor.	price>
R-R-4637	Hycanthone CAS No.3105-97-3	Hycanthone/CAS No.3105-97-3 is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.	price>
R-C-2968	SB271046 CAS：209481-20-9	SB271046 is a potent,selective and orally active 5-HT6 receptor antagonist with pKi of 8.9,exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.	price>
R-R-4638	Branaplam hydrochloride CAS No.1562338-39-9	Branaplam (LMI070; NVS-SM1) hydrochloride/CAS No.1562338-39-9 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model	price>
R-C-2969	SB269652 CAS：215802-15-6	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor(D2R).SB269652 binds in a bitopic manner at one protomer of a D2R dimer and modulates the binding of dopamine at a second protomer.	price>
R-R-4639	Galidesivir CAS No.249503-25-1	Galidesivir (BCX4430)/CAS No.249503-25-1, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.	price>

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