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Catalog	name	Description	price
R-C-2809	LY 344864 CAS:186544-26-3	LY344864 is a selective receptor agonist with an affinity of 6 nM(Ki)at the recently cloned 5-HT1F receptor.	price>
R-R-4509	N-Nitroso-N-methylurea CAS No.684-93-5	N-Nitroso-N-methylurea (NMU;MNU;NMH)/CAS No.684-93-5 is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane.	price>
R-C-2810	L 760735 CAS:188923-01-5	High affinity NK1 receptor antagonist(IC50=0.19nM at human NK1 receptors). Selective(>300-fold)over h-NK2 and h-NK3 receptors.Exhibits anxiolytic and antidepressant-like effects.	price>
R-R-4510	Azoxymethane CAS No.25843-45-2	Azoxymethane/AOM/CAS No.25843-45-2 is a colon carcinogen which leads to the formation of DNA adducts.	price>
R-C-2811	NGB 2904 CAS:189060-98-8	NGB 2904 is an orally active and selective dopamine(DA)D3 receptor antagonist.NGB 2904 can be used for the research of cocaine addiction.	price>
R-R-4511	Phosphoramide mustard cyclohexanamine CAS No.1566-15-0	Phosphoramide mustard cyclohexanamine/CAS No.1566-15-0 is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage.	price>
R-C-2812	Firocoxib CAS:189954-96-9	Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class,currently approved for use in dogs and horses.	price>
R-R-4512	Calicheamicin CAS No.108212-75-5	Calicheamicin/CAS No.108212-75-5, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-2813	Bepotastine Besilate CAS:190786-44-8	Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist.Bepotastine besilate has the potential for allergic rhinitis,allergic conjunctivitis and urticaria/pruritus research.	price>
R-R-4513	Lurbinectedin CAS No.497871-47-3	Lurbinectedin (PM01183)/CAS No.497871-47-3 is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.	price>
R-C-2814	LY 379268 CAS:191471-52-0	LY379268 is a potent,selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69nM(mGlu2)and 4.48nM(mGlu3).LY379268 has no activity on human mGlu 1a,4a,5a or 7a receptors.LY379268 has antioxidant and neuroprotective effects.	price>
R-R-4514	SG3199 CAS No.1595275-71-0	SG3199/CAS No.1595275-71-0 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249).	price>
R-R-4515	Tesirine CAS No.1595275-62-9	Tesirine (SG3249)/CAS No.1595275-62-9 is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity.	price>
R-R-4516	Lomustine CAS No.13010-47-4	Lomustine (CCNU; NSC 79037)/CAS No.13010-47-4 is a DNA alkylating agent, with antitumor activity.	price>
R-R-4517	Procarbazine Hydrochloride CAS No.366-70-1	Procarbazine Hydrochloride/CAS No.366-70-1 is an orally active alkylating agent, with anticancer activity. Procarbazine Hydrochloride can be used in Hodgkin disease research.	price>
R-R-4518	Thio-TEPA CAS No.52-24-4	Thio-TEPA is a sulfur-containing nitrogen mustard alkylating agent, belonging to anti-tumor drugs. Its structure is similar to TEPA (triethylenetetramine), but it enhances chemical activity and cytotoxicity by replacing some nitrogen atoms with sulfur atoms. Application areas: Anti tumor treatment: mainly used for chemotherapy of breast cancer, ovarian cancer, bladder cancer and other solid tumors, especially for metastatic tumors. Immune regulation: At high doses, it can inhibit bone marrow hematopoietic function and is used for pre-treatment before hematopoietic stem cell transplantation.	price>
R-C-2849	RS 127445 CAS:199864-87-4	RS-127445(MT500)is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4,exhibits >1000-fold selectivity against other 5-HT receptors.	price>
R-R-4519	SJG-136 CAS No.232931-57-6	SJG-136/CAS No.232931-57-6 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA. SJG-136 has potent antitumor activity.	price>
R-C-2850	DOPE-PDP	Dope conjugated polyethylene glycol is a combination of phospholipids and polyethylene glycol,which has hydrophilicity and hydrophobicity.	price>
R-R-4520	Duocarmycin TM CAS No.157922-77-5	Duocarmycin TM (CBI-TMI)/CAS No.157922-77-5 is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.	price>

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