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Catalog	name	Description	price
R-C-2773	A-867744 CAS:1000279-69-5	A-867744 is a highly potent and selective type II positive allosteric modulator(PAM)of the alpha7 nicotinic acetylcholine receptors(nAChR)with an EC50 of 1.0μM.	price>
R-R-4473	DEG-77 CAS No.3032265-06-5	DEG-77/CAS No.3032265-06-5, a PROTAC based IKZF2 and CK1α degrader, possesses suitable pharmacokinetic properties, solubility, and selectivity for in vivo studies (t1/2=8h).	price>
R-C-2774	Desloratadine CAS:100643-71-8	Desloratadine(Sch34117)is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine.Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.	price>
R-R-4474	TMX-4116 CAS No.2766385-56-0	TMX-4116/CAS No.2766385-56-0 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma.	price>
R-C-2775	Rotundine CAS:483-14-7	Rotundine(L-tetrahydropalmatine,L-THP)is a selective dopamine D1 receptor antagonist with IC50 of 166nM.	price>
R-R-4475	Silmitasertib sodium salt CAS No.1309357-15-0	Silmitasertib sodium salt/CAS No.1309357-15-0 is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α.	price>
R-R-4476	TBB CAS No.17374-26-4	TBB/NSC 231634/Casein Kinase II Inhibitor I/CAS No.17374-26-4 is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.	price>
R-C-2776	Ebrotidine CAS:100981-43-9	Ebrotidine(FI 3542)is a competitive H2-receptor antagonist(Ki=27.5nM)with a potent antisecretory activity and evidenced gastroprotection.	price>
R-C-2777	CY 208-243 CAS：100999-26-6	CY 208-243 is a drug which acts as a dopamine agonist selective for the D1subtype.Unlike most D1-selective agonists,it shows efficacy in animal models of Parkinson is disease.	price>
R-R-4477	PF-4800567 CAS No.1188296-52-7	PF-4800567/CAS No.1188296-52-7 is a potent and selective inhibitor of casein kinase 1ϵ (CK1ϵ), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).	price>
R-C-2778	Talipexole CAS：101626-70-4	Talipexole(B-HT920)is a dopamine agonist that has been proposed as an antiparkinsonian agent.	price>
R-R-4478	DMAT CAS No.749234-11-5	DMAT/CK2 Inhibitor/Casein kinase II Inhibitor/CAS No.749234-11-5 is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.	price>
R-C-2779	ARN2966 CAS：102212-26-0	ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.	price>
R-R-4479	FPFT-2216 CAS No.2367619-87-0	FPFT-2216/CAS No.2367619-87-0, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). FPFT-2216 can be used for the research of cancer and inflammatory disease.	price>
R-C-2780	Otenzepad (AF-DX 116) CAS：102394-31-0	Otenzepad(AF-DX 116)is a selective and competitive M2 muscarinic acetylcholine receptor antagonist,with IC50 values of 640nM and 386nM for rabbit peripheral lung and rat heart,respectively.	price>
R-R-4480	SSTC3 CAS No.1242422-09-8	SSTC3/CAS No.1242422-09-8 is a casein kinase 1α (CK1α) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors.	price>
R-C-2781	VUF 10460 CAS：1028327-66-3	VUF10460 is a non-imidazole histamine H4 receptor agonist;binds to rat H4 receptor with a pKi of 7.46.	price>
R-R-4481	IC261 CAS No.186611-52-9	IC261/CAS No.186611-52-9 is a selective, ATP-competitive CK1 inhibitor, with IC50s of 1 μM, 1 μM, 16 μM for Ckiδ, Ckiε and Ckiα1, respectively.	price>
R-C-2782	Sumatriptan CAS:103628-46-2	Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D,5-HT1B and 5-HT1A.	price>
R-R-4482	SGC-CK2-1 CAS No.2470424-39-4	SGC-CK2-1/CAS No.2470424-39-4 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC50s of 36 and 16 nM for CK2α and CK2α′respectively in the nanoBRET assay. SGC-CK2-1 can be used for the research of neurodegenerative diseases.	price>

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