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Catalog	name	Description	price
R-R-4565	3,6-Dichlorotrimellitic acid CAS No.137071-78-4	3,6-Dichlorotrimellitic acid/CAS No.137071-78-4 is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.	price>
R-C-2896	PCL5K-PEG2K-urea	PCL-PEG-urea,PCL peg urea is a triblock copolymer with hydroxyl at the end of hydrophobic block.Biocompatible peg copolymers with biodegradable polyester segments can be used to prepare core-shell micelles,nanoparticles and microspheres.	price>
R-R-4566	Nedisertib CAS No.1637542-33-6	Nedisertib (M3814)/CAS No.1637542-33-6 is a potent orally available selective DNA-PK inhibitor, with an IC50 of <3 nM. Anti-tumor activity.	price>
R-C-2897	Biotin-PEG-Hyd-PCL	Ruixi bio supplies environmentally responsive copolymer products(disulfide bond, hydrazone bond and citric acid) which are connected between two different polymers with disulfide bond or hydrazone bond or citric acid to make them redox sensitive and pH responsive.Different polymers include PEG、PEI、Hyaluronate、Dextran、Chitosan、PLGA、PCL、PLA、P2VP、PAA、PMMA etc.	price>
R-R-4567	VX-984 CAS No.1476074-39-1	VX-984/CAS No.1476074-39-1 is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor. VX-984 efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks). VX-984 can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research. VX-984 is a de novo deuterium.	price>
R-C-2898	PCL-PEG-RPKPQQFFGLM	Polyethylene glycol derivatives can increase solubility and stability and reduce the immunogenicity of peptides and proteins.It can also inhibit the nonspecific binding of charged molecules on the modified surface.It is widely used in pharmaceutical research,drug sustained release,nano new material research and cell culture.In the study of ligands of active compounds, polypeptide synthesis carriers and polymer grafted compounds.	price>
R-R-4568	CC-115 CAS No.1228013-15-7	CC-115/CAS No.1228013-15-7 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.	price>
R-C-2899	SH-PEG-PLL-Folate	Folate polyethylene glycol polylysine is a linear amphiphilic block copolymer with PLL as hydrophobic part and PEG as hydrophilic part.The PLL moiety has side chain free amino groups.PEG-PLL can be self-assembled into micelles with functional PLL core for drug and gene delivery.Folate has a high affinity folate receptor,which can be used to target cell membrane receptors for drug delivery.	price>
R-R-4569	BAY-8400 CAS No.2763602-59-9	BAY-8400/CAS No.2763602-59-9 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (IC50=81 nM). BAY-8400 can be used for the research of cancer.	price>
R-C-2900	PGA-PEG-NH2	Poly(L-glutamic acid)-poly (ethylene glycol)-amine is a linear amphiphilic block copolymer(ABC),which has poly(glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part.ABC can self assemble into micelles.It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4570	CC-115 hydrochloride CAS No.1300118-55-1	CC-115 hydrochloride/CAS No.1300118-55-1 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.	price>
R-C-2901	PGA-PEG-N3	poly(L-glutamic acid)-poly(ethylene glycol)-azide is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as hydrophobic part and azide functionalized peg as hydrophilic part. ABC can self assemble into micelles. Under the catalysis of copper catalyst, azide can click cyclization with alkynyl in aqueous solution to form nitrogen-containing five membered heterocycles.	price>
R-R-4571	(R)-VX-984 CAS No.2448475-19-0	(R)-VX-984/(R)-M9831/CAS No.2448475-19-0 is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor.	price>
R-C-2902	PGA-PEG-SH	poly(L-glutamic acid)-poly(ethylene glycol)-Thiol is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part. ABC can self assemble into micelles. It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4572	VVD-214 CAS No.3026500-20-6	VVD-214/RO7589831/VVD-133214/CAS No.3026500-20-6 is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers.	price>
R-C-2903	PGA-PEG-Folate	poly(L-glutamic acid)-poly(ethylene glycol)-Folate is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part. ABC can self assemble into micelles. It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4573	Dibenz[a,h]anthracene CAS No.53-70-3	Dibenz[a,h]anthracene (DBA)/CAS No.53-70-3 is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms.	price>
R-R-4574	KY386 CAS No.2787598-01-8	KY386/CAS No.2787598-01-8 is a potent, selective inhibitor of DHX33 helicase, with the IC50 of 19 nM. KY386 inhibits U251-MG cells (DHX33-overexpressing cancer cell strain) with IC50 of 20 nM.and shows potent anti-cancer activity and moderate metabolic stability.	price>
R-C-2905	PLGA-b-PDLGA	PDLGA also known as poly (lactic acid glycolic acid) copolymer and poly (lactic acid glycolic acid) copolymer, consists of two monomers acid and glycolic acid random polymerization, is a kind of biodegradable functional polymer organic compounds, with good biocompatibility, non-toxic, good encapsulation and film-forming properties, is widely used in pharmaceutical, medical engineering materials and modern industrial fields.	price>
R-R-4575	Methotrexate CAS No.59-05-2	Methotrexate (Amethopterin)/CAS No.59-05-2, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).	price>

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