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Catalog	name	Description	price
R-R-4643	Braco-19 CAS No.351351-75-2	Braco-19/CAS No.351351-75-2 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-C-2974	NPS 2390 CAS:226878-01-9	NPS2390 is a group I mGlu antagonist. It displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket.Only for scientific research, not for human body.	price>
R-R-4644	Dithranol CAS No.1143-38-0	Dithranol (Anthralin)/CAS No.1143-38-0 is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair.	price>
R-C-2975	Lofepramine CAS# 23047-25-8	Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535).Only for scientific research, not for human body.	price>
R-R-4645	Ethynylcytidine CAS No.180300-43-0	Ethynylcytidine (ECyD)/CAS No.180300-43-0, a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-2976	PD 102807 CAS:23062-91-1	PD 102807 is an m4 muscarinic receptor antagonist with an IC50 of 90.7 nm.PD 102807 inhibited M1,M2,m3 and M5 muscarinic receptors with IC50 of 6558.7,3440.7,950.0 and 7411.7nm, respectively. It has the effect of anti dyskinesia.Only for scientific research, not for human body.	price>
R-R-4646	TTP-8307 CAS No.950225-08-8	TTP-8307/CAS No.950225-08-8 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP).	price>
R-C-2977	Bay 36-7620 CAS:232605-26-4	Selective mGlu1 receptor non-competitive antagonist (IC50 = 0.16 μM) with inverse agonist activity. Impairs classical conditioning and associated synaptic plasticity in hippocampal neurons. Exhibits neuroprotective and anticonvulsive effects in vivo following systemic administration.Only for scientific research, not for human body.	price>
R-R-4647	Neobavaisoflavone CAS No.41060-15-5	Neobavaisoflavone/CAS No.41060-15-5, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation.	price>
R-R-4648	BRD32048 CAS No.433694-46-3	BRD32048/CAS No.433694-46-3 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen.	price>
R-R-4649	Cinoxacin CAS No.28657-80-9	Cinoxacin (Compound 64716)/CAS No.28657-80-9, a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.	price>
R-R-4650	Deoxyguanosine triphosphate trisodium salt CAS No.93919-41-6	Deoxyguanosine triphosphate (dGTP) trisodium salt/CAS No.93919-41-6 is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.	price>
R-R-4651	Braco-19 trihydrochloride CAS No.1177798-88-7	Braco-19 trihydrochloride/CAS No.1177798-88-7 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-R-4652	NVS-SM2 CAS No.1562333-92-9	NVS-SM2/CAS No.1562333-92-9 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research.	price>
R-R-4653	ERCC1-XPF-IN-2 CAS No.1808986-37-9	ERCC1-XPF-IN-2/CAS No.1808986-37-9 is a potent ERCC1-XPF endonuclease inhibitor with an IC50 value of 0.6 µM. ERCC1-XPF-IN-2 shows activity in nucleotide excision repair, cisplatin enhancement and γH2AX assays.	price>
R-C-2984	Ro 28-1675 CAS:300353-13-3	Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24,0.0019 uM.Only for scientific research, not for human body.	price>
R-R-4654	Anticancer agent 73 CAS No.124811-87-6	Anticancer agent 73 (compound CIB-3b)/CAS No.124811-87-6 is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo.	price>
R-C-2985	PF-07321332 cas:2628280-40-8	PF-07321332(Paxlovid)is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. Only for scientific research, not for human body.	price>
R-R-4655	L82-G17 CAS No.92285-87-5	L82-G17/CAS No.92285-87-5 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity.	price>
R-C-2986	Ro5-3335 CAS# 30195-30-3	Ro5-3335 is a benzodiazepine compound, which can be used as a core binding factor (CBF) leukemia inhibitor. Ro5-3335 is runx1-cbf β Interaction inhibitors can inhibit Runx1 / CBFB dependent trans activation. Only for scientific research, not for human body.	price>

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