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Catalog	name	Description	price
R-C-2963	5,10,15,20-Tetrakis(3,5-dihydroxyphenyl)porphyrin cas 145764-54-1	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme).These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable4634.	price>
R-R-4633	Pyrazofurin CAS No.30868-30-5	Pyrazofurin/CAS No.30868-30-5, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5-phosphate (UMP) synthase. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 µM in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C.	price>
R-C-2964	5,10,15,20-Tetrakis(3,5-dimethoxyphenyl )-21H,23H-porphyrin Cas:74684-34-7	Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme). These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable.	price>
R-R-4634	ccc_R08 CAS No.2919019-72-8	ccc_R08/CAS No.2919019-72-8 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection.	price>
R-C-2965	SB-269970	SB269970 is a potent and selective 5-HT7 receptor antagonist.	price>
R-R-4635	R-1479 CAS No.478182-28-4	R-1479/CAS No.478182-28-4, a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.	price>
R-C-2966	Etoricoxib CAS：202409-33-4	Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.	price>
R-R-4636	Werner syndrome RecQ helicase-IN-3 CAS No.2869954-98-1	Werner syndrome RecQ helicase-IN-3/CAS No.2869954-98-1 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity.	price>
R-C-2967	Olcegepant CAS：204697-65-4	Olcegepant also known as BIBN-4096 or BIBN-4096BS is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1)receptor.	price>
R-R-4637	Hycanthone CAS No.3105-97-3	Hycanthone/CAS No.3105-97-3 is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.	price>
R-C-2968	SB271046 CAS：209481-20-9	SB271046 is a potent,selective and orally active 5-HT6 receptor antagonist with pKi of 8.9,exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.	price>
R-R-4638	Branaplam hydrochloride CAS No.1562338-39-9	Branaplam (LMI070; NVS-SM1) hydrochloride/CAS No.1562338-39-9 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model	price>
R-C-2969	SB269652 CAS：215802-15-6	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor(D2R).SB269652 binds in a bitopic manner at one protomer of a D2R dimer and modulates the binding of dopamine at a second protomer.	price>
R-R-4639	Galidesivir CAS No.249503-25-1	Galidesivir (BCX4430)/CAS No.249503-25-1, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.	price>
R-C-2970	SB-277011 CAS：215803-78-4	SB-277011 is a drug which acts as a potent and selective dopamine D3 receptor antagonist which is around 80-100x selective for D3 over D2 and lacks any partial agonist activity.	price>
R-R-4640	Gemifloxacin mesylate CAS No.210353-53-0	Gemifloxacin mesylate (SB-265805S; LB-20304a)/CAS No.210353-53-0 is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.	price>
R-C-2971	Lumiracoxib CAS:220991-20-8	Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Only for scientific research, not for human body.	price>
R-R-4641	AG-636 CAS No.1623416-31-8	AG-636/CAS No.1623416-31-8 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. AG-636 has strong anticancer effects.	price>
R-R-4642	BCH001 CAS No.384859-58-9	BCH001/CAS No.384859-58-9, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging.	price>
R-C-2973	Adoprazine (SLV313) CAS:222551-17-9	Adoprazine,also known as SLV313,is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug. Adoprazine is part of the Antidepressant Agent group.Only for scientific research, not for human body.	price>

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