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Catalog	name	Description	price
R-R-4462	CCT241736 CAS No.1402709-93-6	CCT241736/CAS No.1402709-93-6 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).	price>
R-C-2763	DGAT1-IN-1 CAS：1449779-49-0	DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of<10nM(cell lysate from Hep3B cells overexpressing human DGAT1).	price>
R-R-4463	Aurora kinase inhibitor-3 CAS No.879127-16-9	Aurora kinase inhibitor-3/CAS No.879127-16-9 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket.	price>
R-C-2764	Pralatrexate (NSC 754230) CAS：146464-95-1	Pralatrexate(NSC 754230)is an antifolate, and structurally a folate analog.Its IC50 is<300nM in some cell lines.Pralatrexate induces tumor cell apoptosis.	price>
R-R-4464	dAURK-4 hydrochloride	dAURK-4 hydrochloride, an Alisertib derivative, is a potent and selective AURKA (Aurora A) degrader. dAURK-4 hydrochloride has anticancer effects.	price>
R-C-2765	Pitavastatin(NK-104) CAS:147526-32-7	Pitavastatin Calcium(NK-104,P-872441,itavastatin,nisvastatin),a novel member of the medication class of statins,is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor.Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation.	price>
R-R-4465	AKI603 CAS No.1432515-73-5	AKI603/CAS No.1432515-73-5 is an inhibitor of Aurora kinase A (AurA), with an IC50 of 12.3 nM. AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells.	price>
R-R-4466	Tinengotinib CAS No.2230490-29-4	Tinengotinib/CAS No.2230490-29-4 is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase. Tinengotinib has the potential for the research of these kinase abnormalities diseases mediated, especially cancer-related diseases (extracted from patent WO2018108079A1).	price>
R-C-2767	YM 511 CAS:148869-05-0	Orally active,potent aromatase(CYP19)inhibitor(IC50 values are 0.4 and 0.12nM at rat ovary and human placenta cells respectively)that only weakly inhibits the synthesis of other steroid hormones.Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro(IC50=0.13nM).	price>
R-R-4467	Aurora kinase inhibitor-8 CAS No.2133001-88-2	Aurora kinase inhibitor-8/CAS No.2133001-88-2 is a highly selective inhibitor of the Aurora kinases.	price>
R-C-2768	PDN01791 CAS:149301-79-1	PDN01791（Arachidonyl Trifluoromethyl Ketone）is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group.It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s.	price>
R-R-4468	TC-A 2317 hydrochloride CAS No.1245907-03-2	TC-A 2317 hydrochloride/CAS No.1245907-03-2 is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity.	price>
R-C-2769	MOG (35-55) CAS:149635-73-4	Myelin oligodendrocyte glycoprotein(MOG)35-55 is a minor component of CNS myelin.Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination,common to the manifestations of multiple sclerosis.Induces strong T and B cell responses and is highly encephalitogenic.	price>
R-R-4469	Aurora Kinases-IN-3 CAS No.2840558-83-8	Aurora Kinases-IN-3 (Compound 15a)/CAS No.2840558-83-8 is an orally active AURKB inhibitor that elicits an AURKB-suppressive activity by disrupting the mitotic localization of AURKB, rather than inhibiting its phosphorylation of H3 at Ser10.	price>
R-C-2770	JJKK 048 CAS:1515855-97-6	JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase(MAGL).	price>
R-R-4470	SCH-1473759 CAS No.1094069-99-4	SCH-1473759/CAS No.1094069-99-4 is an aurora inhibitor with IC50s of 4 and 13 nM for aurora A and B, respectively.	price>
R-C-2771	Cilomilast CAS:153259-65-5	Cilomilast(SB-207499)is a potent,selective and orally active inhibitor of Phosphodiesterase 4(PDE4),with IC50s of ~100 and 120nM for LPDE4 and HPDE4,respectively.Cilomilast shows selectivity for PDE4 over PDE1,PDE2,PDE3 and PDE5(IC50=74,65,>100,and 83µM,respectively).	price>
R-R-4471	AAPK-25 CAS No.2247919-28-2	AAPK-25/CAS No.2247919-28-2 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. AAPK-25 targets Aurora-A, -B, and -C with Kd values ranging from 23-289 nM, as well as PLK-1, -2, and -3 with Kd values ranging from 55-456 nM.	price>
R-C-2772	DMP 777 CAS:157341-41-8	DMP-777(L 694458)is a potent and orally active Leukocyte elastase(HLE)inhibitor.Oral dosing with DMP 777 caused a rapid increase in serum gastrin levels and severe hypochlorhydria.DMP 777 inhibited aminopyrine accumulation into rabbit parietal cells stimulated with either histamine or forskolin.	price>
R-R-4472	SJ3149 CAS No.3026986-17-1	SJ3149/CAS No.3026986-17-1 is a selective and potent degrader of CK1α protein in vitro and in vivo. SJ3149 has antitumor activity.	price>

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