Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-C-2854	PAE-SS-PEG	RuixiBiotechCo.Ltd sells drug delivery and nano targetrelated R&D reagents,our products are phospholipid,polyethylene glycolderivatives,block copolymers,gold nanoparticles,magnetic nanoparticles,fluorescent dyes,microsphere.	price>
R-R-4524	Melflufen hydrochloride CAS No.380449-54-7	Melflufen (Melphalan flufenamide) hydrochloride/CAS No.380449-54-7, a dipeptide proagent of Melphalan, is an alkylating agent. Melflufen hydrochloride shows antitumor activity against multiple myeloma (MM) cells and inhibits angiogenesis. Melflufen hydrochloride induces irreversible DNA damage and cytotoxicity in MM cells.	price>
R-C-2855	TPP-PEG-TK-PLGA	ROS is a by-product of normal aerobic metabolism and plays an important role in cell signal transduction and dynamic balance.The high concentration of ROS in tumor cells is because the stimulation of oncogenes increases the metabolic activity of tumor cells.At the same time,the disorder of mitochondrial function also leads to the increase of ROS concentration in tumor cells.TPP is a white odorless tablet or powder crystal,insoluble in water,soluble in ethanol,easily soluble in organic solvents such as benzene,chloroform,ethylene and acetone, and also soluble in vegetable oil.It has low volatility,transparency,softness, toughness,plasticization,flame retardancy and excellent light stability.	price>
R-R-4525	Treosulfan CAS No.299-75-2	Treosulfan (NSC 39069)/CAS No.299-75-2 is a bifunctional alkylating agent with activity in ovarian cancer and other solid tumor types.	price>
R-C-2856	Oil soluble CsPbBr3 quantum dots	Perovskite quantum dots have high electron hole mobility,high luminous efficiency,wide absorption spectrum and narrow emission spectrum.They can adjust the color and make the luminous spectrum adjustable only by changing the size of quantum dots.Therefore,they have high application potential and unique advantages in the fields of solar energy cells,solid-state lighting and display.	price>
R-R-4526	OBI-3424 CAS No.2097713-68-1	OBI-3424 (TH-3424)/CAS No.2097713-68-1 is a proagent that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. OBI-3424 can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research.	price>
R-C-2857	DSPE-PEG2000-sucrose	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.so the drug stability is better, even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Sucrose,organic compound,molecular weight 342.3.Colorless crystal,with optical rotation,but no variable rotation.	price>
R-R-4527	Illudin S CAS No.1149-99-1	Illudin S/CAS No.1149-99-1, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells.	price>
R-C-2858	DSPE-PEG2000-L-valine	Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.	price>
R-R-4528	PIP-199 CAS No.622795-76-0	PIP-199/CAS No.622795-76-0 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.	price>
R-C-2861	PCL-TK-PEG	Polyglutamic acid is a polymer of the amino acid glutamic acid.ROS is a by-product of normal aerobic metabolism and plays an important role in cell signal transduction and dynamic balance.	price>
R-R-4529	Tretazicar CAS No.21919-05-1	Tretazicar (CB 1954)/CAS No.21919-05-1, an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1).	price>
R-R-4530	SG2057 CAS No.260417-62-7	SG2057 (DRG16)/CAS No.260417-62-7 is a PBD dimer containing a pentyldioxy linkage which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts. SG2057 is a highly active antitumor agent.	price>
R-R-4531	Nimustine hydrochloride CAS No.55661-38-6	Nimustine hydrochloride (ACNU)/CAS No.55661-38-6 is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for glioblastomas.	price>
R-C-2862	PAMAM G0-Polyglutamic acid 50（4）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4532	PK11000 CAS No.38275-34-2	PK11000/CAS No.38275-34-2 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities.	price>
R-C-2863	PEG77(2)-PAMAM G0-Polyglutamic acid 50（2）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4533	Imifoplatin CAS No.1339960-28-9	Imifoplatin (PT-112)/CAS No.1339960-28-9 is a platinum-based agent belonging to the phosphaplatin family. Imifoplatin exhibits antineoplastic activity.	price>
R-C-2864	PEG77(1)-PAMAM G0-Polyglutamic acid50（3）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4534	Duocarmycin SA CAS No.130288-24-3	Duocarmycin SA/CAS No.130288-24-3 is an orally active antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro.	price>

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