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Catalog	name	Description	price
R-R-4580	Remdesivir CAS No.1809249-37-3	Remdesivir (GS-5734)/CAS No.1809249-37-3, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells and 30 nM for murine hepatitis virus in brain tumor cells delayed. Remdesivir is highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro.	price>
R-C-2911	P3-4HB-PEG	Through the selective coupling reaction between hydroxyl terminated P3-4HB segment and isocyanate end group, an alternating block polyurethane ppg-peg-ppg segment based on poly 3-hydroxybutyrate-co-4-hydroxybutyrate (P3-4HB glycol) and poly propylene glycol polyethylene glycol poly propylene glycol (ppg-peg-ppg) was synthesized, using 1,6-hexamethylene diisocyanate (HDI) as capping agent.	price>
R-R-4581	Brequinar CAS No.96187-53-0	Brequinar (DUP785)/CAS No.96187-53-0 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.	price>
R-C-2912	PHBHHx-PEG	Hydroxybutyric acid and hydroxyhexanoic acid copolymer (PHBHHx),When the ratio of PHBHHx to peg is 3:1and 2 :1,they are completely physically compatible.The increase of the proportion of PEG in the blend leads to phase separation and becomes a partially compatible system.PEG incorporation significantly improved the hydrophilicity and surface free energy of the materials,and significantly improved the cell adhesion and proliferation of vascular smooth muscle cells(RASMCs)and vascular endothelial cells(HUVECs),both of which were dependent on PEG content.	price>
R-R-4582	a-Amanitin CAS No.23109-05-9	α-Amanitin/CAS No.23109-05-9 is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.	price>
R-C-2913	PSO-PEO-PSO	RuixiBiotechCo.Ltd sells drug delivery and nano targetrelated R&D reagents, our products are phospholipid, polyethylene glycolderivatives, block copolymers, gold nanoparticles, magnetic nanoparticles,fluorescent dyes, microsphere.	price>
R-R-4583	Branaplam CAS No.1562338-42-4	Branaplam (LMI070; NVS-SM1)/CAS No.1562338-42-4 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.	price>
R-R-4584	Plicamycin CAS No.18378-89-7	Plicamycin (Mithramycin A)/CAS No.18378-89-7 is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein. Plicamycin inhibits GSTM2 promoter activity and protein expression.	price>
R-C-2915	PAMAM-PEG-Active esters	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.	price>
R-R-4585	GS-441524 CAS No.1191237-69-0	GS-441524/CAS No.1191237-69-0, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM.	price>
R-R-4586	Novobiocin sodium CAS No.1476-53-5	Novobiocin (Albamycin) sodium/CAS No.1476-53-5 is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity.	price>
R-C-2917	PAMAM-PEG-EPOX	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.	price>
R-R-4587	IMT1 CAS No.2304621-31-4	IMT1/CAS No.2304621-31-4 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases.	price>
R-C-2918	PAMAM-PEG-HZ	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.	price>
R-R-4588	Idarubicin hydrochloride CAS No.57852-57-0	Idarubicin hydrochloride/CAS No.57852-57-0 is an anthracycline antileukemic agent. It inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin hydrochloride inhibits the growth of bacteria and yeasts.	price>
R-C-2919	PAMAM-PEG-NPC	Nitrophenyl carbonate PEG derivatives can be used to modify proteins, peptides and other materials through amino acids or other acid active chemical groups. PEG derivatives can increase solubility and stability and reduce immunogenicity of peptides and proteins.Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.	price>
R-R-4589	Risdiplam CAS No.1825352-65-5	Risdiplam (RG7916)/CAS No.1825352-65-5 is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels.	price>
R-C-2920	PAMAM-PEG-OPSS	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.	price>
R-R-4590	ML216 CAS No.1430213-30-1	ML216 (CID-49852229)/CAS No.1430213-30-1 is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 µM. Antitumor avtivity.	price>
R-C-2921	PAMAM-PLA-EPOX	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization Ethylene oxide is an important intermediate in organic synthesis, which is used to prepare ethylene glycol, antifreeze, synthetic detergent, emulsifier and plastics.	price>

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