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Catalog | name | Description | price |
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R-C-2802 | MSPG CAS:169209-64-7 | Relatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors. | price> |
R-R-4502 | Casein kinase 1o-IN-8 CAS No.851396-73-1 | Casein kinase 1δ-IN-8 (compound 494)/CAS No.851396-73-1 is an inhibitor of Casein kinase 1δ, Casein kinase 1δ-IN-8 can be used in the treatment of neurodegenerative disorders such as Alzheimer disease. | price> |
R-C-2803 | MTPG CAS:169209-66-9 | MTPG is a group II/group III mGlu antagonist,showing selectivity for group II in electrophysiological studies.MTPG is a potent antagonist for(1S,3S)-ACPD-sensitive receptors;preference for group II mGluR. | price> |
R-R-4503 | Casein kinase 1o-IN-1 CAS No.851871-94-8 | Casein kinase 1δ-IN-1 (compound 822)/CAS No.851871-94-8 is an inhibitor of casein kinase 1 delta (CK1δ), exhibits inhibition of greater than 5%. Casein kinase 1δ-IN-1 can be used for neurodegenerative disorders such as Alzheimer disease research. | price> |
R-C-2804 | Eglumegad (LY354740) CAS:176199-48-7 | Eglumegad(LY354740)is a highly potent and selective group II(mGlu2/3)receptor agonist with IC50s of 5 and 24nM on transfected human mGlu2 and mGlu3 receptors,respectively. | price> |
R-R-4504 | ON 108600 CAS No.1585246-23-6 | ON 108600/CAS No.1585246-23-6 is a inhibitor for CK2 (Casein Kinase2)/TNIK/DYRK1 , with the IC50s for DYRK1A/DYRKB, DYRK2, CK2α1/CK2α2, and TNIK of 0.016 μm/0.007 μM, 0.028 μM, 0.05 μM/0.005 μM, and 0.005 μM, respectively. ON 108600 has antitumor activity. | price> |
R-C-2805 | NKP608 CAS:177707-12-9 | NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective,specific and potent antagonist at the neurokinin-1(NK-1)receptor both in vitro(IC50=2.6nM)and in vivo. | price> |
R-R-4505 | Casein kinase 1o-IN-9 CAS No.854355-54-7 | Casein kinase 1δ-IN-9 (compound 737)/CAS No.854355-54-7 is a potent casein kinase 1δ (CK1δ/CK15) inhibitor. Casein kinase 1δ-IN-9 can be used for the research of neurodegenerative disorders such as Alzheimer disease. | price> |
R-C-2806 | Sumanirole maleate CAS:179386-44-8 | Sumanirole maleate(U-95666E;PNU-95666E)is a highly selective D2 receptor full agonist with an ED50 of about 46nM.Sumanirole was developed for the treatment of Parkinson is disease and restless leg syndrome. | price> |
R-R-4506 | Casein kinase 1o-IN-7 CAS No.764694-25-9 | Casein kinase 1δ-IN-7 (compound 497)/CAS No.764694-25-9 is a Casein kinase 1δ inhibitor. Casein kinase 1δ-IN-7 can be used in the study of neurodegenerative disorders such as Alzheimer disease. | price> |
R-C-2807 | SDZ NKT 343 CAS:180046-99-5 | SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist that antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo. | price> |
R-R-4507 | Casein kinase 1o-IN-3 CAS No.349438-77-3 | Casein kinase 1δ-IN-3 (Compound 23a)/CAS No.349438-77-3 is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M. | price> |
R-C-2808 | Almotriptan Malate CAS:181183-52-8 | Almotriptan malate(Axert)is a selective 5-hydroxytryptamine1B/1D(5-HT1B/1D) receptor agonist,used for the treatment of Migraine attacks in adults. | price> |
R-R-4508 | Cyclophosphamide CAS No.50-18-0 | Cyclophosphamide/CAS No.50-18-0 is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | price> |
R-C-2809 | LY 344864 CAS:186544-26-3 | LY344864 is a selective receptor agonist with an affinity of 6 nM(Ki)at the recently cloned 5-HT1F receptor. | price> |
R-R-4509 | N-Nitroso-N-methylurea CAS No.684-93-5 | N-Nitroso-N-methylurea (NMU;MNU;NMH)/CAS No.684-93-5 is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane. | price> |
R-C-2810 | L 760735 CAS:188923-01-5 | High affinity NK1 receptor antagonist(IC50=0.19nM at human NK1 receptors). Selective(>300-fold)over h-NK2 and h-NK3 receptors.Exhibits anxiolytic and antidepressant-like effects. | price> |
R-R-4510 | Azoxymethane CAS No.25843-45-2 | Azoxymethane/AOM/CAS No.25843-45-2 is a colon carcinogen which leads to the formation of DNA adducts. | price> |
R-C-2811 | NGB 2904 CAS:189060-98-8 | NGB 2904 is an orally active and selective dopamine(DA)D3 receptor antagonist.NGB 2904 can be used for the research of cocaine addiction. | price> |
R-R-4511 | Phosphoramide mustard cyclohexanamine CAS No.1566-15-0 | Phosphoramide mustard cyclohexanamine/CAS No.1566-15-0 is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage. | price> |