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Catalog	name	Description	price
R-C-2900	PGA-PEG-NH2	Poly(L-glutamic acid)-poly (ethylene glycol)-amine is a linear amphiphilic block copolymer(ABC),which has poly(glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part.ABC can self assemble into micelles.It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4570	CC-115 hydrochloride CAS No.1300118-55-1	CC-115 hydrochloride/CAS No.1300118-55-1 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.	price>
R-C-2901	PGA-PEG-N3	poly(L-glutamic acid)-poly(ethylene glycol)-azide is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as hydrophobic part and azide functionalized peg as hydrophilic part. ABC can self assemble into micelles. Under the catalysis of copper catalyst, azide can click cyclization with alkynyl in aqueous solution to form nitrogen-containing five membered heterocycles.	price>
R-R-4571	(R)-VX-984 CAS No.2448475-19-0	(R)-VX-984/(R)-M9831/CAS No.2448475-19-0 is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor.	price>
R-C-2902	PGA-PEG-SH	poly(L-glutamic acid)-poly(ethylene glycol)-Thiol is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part. ABC can self assemble into micelles. It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4572	VVD-214 CAS No.3026500-20-6	VVD-214/RO7589831/VVD-133214/CAS No.3026500-20-6 is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers.	price>
R-C-2903	PGA-PEG-Folate	poly(L-glutamic acid)-poly(ethylene glycol)-Folate is a linear amphiphilic block copolymer (ABC), which has poly (glutamic acid) as a hydrophobic part and azide functionalized peg as a hydrophilic part. ABC can self assemble into micelles. It can self assemble into micelles or form hydrogels for drug delivery.	price>
R-R-4573	Dibenz[a,h]anthracene CAS No.53-70-3	Dibenz[a,h]anthracene (DBA)/CAS No.53-70-3 is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms.	price>
R-R-4574	KY386 CAS No.2787598-01-8	KY386/CAS No.2787598-01-8 is a potent, selective inhibitor of DHX33 helicase, with the IC50 of 19 nM. KY386 inhibits U251-MG cells (DHX33-overexpressing cancer cell strain) with IC50 of 20 nM.and shows potent anti-cancer activity and moderate metabolic stability.	price>
R-C-2905	PLGA-b-PDLGA	PDLGA also known as poly (lactic acid glycolic acid) copolymer and poly (lactic acid glycolic acid) copolymer, consists of two monomers acid and glycolic acid random polymerization, is a kind of biodegradable functional polymer organic compounds, with good biocompatibility, non-toxic, good encapsulation and film-forming properties, is widely used in pharmaceutical, medical engineering materials and modern industrial fields.	price>
R-R-4575	Methotrexate CAS No.59-05-2	Methotrexate (Amethopterin)/CAS No.59-05-2, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).	price>
R-C-2906	PLGA-b-PPG	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs. Most of their carriers are synthetic, biodegradable and thermodynamically stable in aqueous media.	price>
R-C-3036	SF1126 CAS:936487-67-1	SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.Only for scientific research, not for human body.	price>
R-R-4576	Streptozotocin CAS No.18883-66-4	Streptozotocin (Streptozocin)/CAS No.18883-66-4 is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells.	price>
R-R-4577	ART558 CAS No.2603528-97-6	ART558/CAS No.2603528-97-6 is a nanomolar potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer.	price>
R-C-2908	PPO-PEO-PPO	poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) block copolymer is a series of water-soluble non-ionic surfactants composed of different PPO / PEO block ratio and molecular weight. Due to its good temperature response and biocompatibility, PEO-PPO-PEO block copolymers have important applications in the fields of hydrophobic drug solubilization and controlled release, gene therapy and so on.	price>
R-R-4578	Propidium Iodide CAS No.25535-16-4	Propidium Iodide (PI)/CAS No.25535-16-4 is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.	price>
R-C-2909	PEO-PPG-PEO	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs. Most of their carriers are synthetic, biodegradable and thermodynamically stable in aqueous media.	price>
R-R-4579	Gemcitabine hydrochloride CAS No.122111-03-9	Gemcitabine Hydrochloride (LY 188011 Hydrochloride)/CAS No.122111-03-9 is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.	price>
R-C-2910	PEO-PBO	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs.Most of their carriers are synthetic,biodegradable and thermodynamically stable in aqueous media.	price>

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