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Catalog	name	Description	price
R-R-4476	TBB CAS No.17374-26-4	TBB/NSC 231634/Casein Kinase II Inhibitor I/CAS No.17374-26-4 is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.	price>
R-C-2776	Ebrotidine CAS:100981-43-9	Ebrotidine(FI 3542)is a competitive H2-receptor antagonist(Ki=27.5nM)with a potent antisecretory activity and evidenced gastroprotection.	price>
R-C-2777	CY 208-243 CAS：100999-26-6	CY 208-243 is a drug which acts as a dopamine agonist selective for the D1subtype.Unlike most D1-selective agonists,it shows efficacy in animal models of Parkinson is disease.	price>
R-R-4477	PF-4800567 CAS No.1188296-52-7	PF-4800567/CAS No.1188296-52-7 is a potent and selective inhibitor of casein kinase 1ϵ (CK1ϵ), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).	price>
R-C-2778	Talipexole CAS：101626-70-4	Talipexole(B-HT920)is a dopamine agonist that has been proposed as an antiparkinsonian agent.	price>
R-R-4478	DMAT CAS No.749234-11-5	DMAT/CK2 Inhibitor/Casein kinase II Inhibitor/CAS No.749234-11-5 is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.	price>
R-C-2779	ARN2966 CAS：102212-26-0	ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.	price>
R-R-4479	FPFT-2216 CAS No.2367619-87-0	FPFT-2216/CAS No.2367619-87-0, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). FPFT-2216 can be used for the research of cancer and inflammatory disease.	price>
R-C-2780	Otenzepad (AF-DX 116) CAS：102394-31-0	Otenzepad(AF-DX 116)is a selective and competitive M2 muscarinic acetylcholine receptor antagonist,with IC50 values of 640nM and 386nM for rabbit peripheral lung and rat heart,respectively.	price>
R-R-4480	SSTC3 CAS No.1242422-09-8	SSTC3/CAS No.1242422-09-8 is a casein kinase 1α (CK1α) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors.	price>
R-C-2781	VUF 10460 CAS：1028327-66-3	VUF10460 is a non-imidazole histamine H4 receptor agonist;binds to rat H4 receptor with a pKi of 7.46.	price>
R-R-4481	IC261 CAS No.186611-52-9	IC261/CAS No.186611-52-9 is a selective, ATP-competitive CK1 inhibitor, with IC50s of 1 μM, 1 μM, 16 μM for Ckiδ, Ckiε and Ckiα1, respectively.	price>
R-C-2782	Sumatriptan CAS:103628-46-2	Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D,5-HT1B and 5-HT1A.	price>
R-R-4482	SGC-CK2-1 CAS No.2470424-39-4	SGC-CK2-1/CAS No.2470424-39-4 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC50s of 36 and 16 nM for CK2α and CK2α′respectively in the nanoBRET assay. SGC-CK2-1 can be used for the research of neurodegenerative diseases.	price>
R-C-2783	Thioperamide CAS:106243-16-7	Thioperamide(MR-12842)is a potent,orally available,brain penetrant and selective H3 receptor antagonist with a Ki of 4.3nM for inhibition of [3H]histamine release.Thioperamide inhibits [3H]histamine synthesis with a Ki of 31nM.	price>
R-R-4483	TAK-715 CAS No.303162-79-0	TAK-715/CAS No.303162-79-0 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model.	price>
R-C-2784	Risperidone CAS:106266-06-2	Risperidone is a serotonin 5-HT2 receptor blocker,P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist,with Kis of 4.8,5.9nM for 5-HT2A and dopamine D2 receptor,respectively.	price>
R-R-4484	CKI-7 free base CAS No.120615-25-0	CKI-7 free base/CAS No.120615-25-0 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases.	price>
R-C-2785	A 987306 CAS:1082954-71-9	A-987306 is a potent histamine H4 receptor antagonist that is selective for H3,H1 and H2 receptors.A-987306 blocks zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo.	price>
R-R-4485	BioE-1115 CAS No.1268863-35-9	BioE-1115/CAS No.1268863-35-9 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.	price>

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