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Catalog	name	Description	price
R-R-4528	PIP-199 CAS No.622795-76-0	PIP-199/CAS No.622795-76-0 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.	price>
R-C-2861	PCL-TK-PEG	Polyglutamic acid is a polymer of the amino acid glutamic acid.ROS is a by-product of normal aerobic metabolism and plays an important role in cell signal transduction and dynamic balance.	price>
R-R-4529	Tretazicar CAS No.21919-05-1	Tretazicar (CB 1954)/CAS No.21919-05-1, an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1).	price>
R-R-4530	SG2057 CAS No.260417-62-7	SG2057 (DRG16)/CAS No.260417-62-7 is a PBD dimer containing a pentyldioxy linkage which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts. SG2057 is a highly active antitumor agent.	price>
R-R-4531	Nimustine hydrochloride CAS No.55661-38-6	Nimustine hydrochloride (ACNU)/CAS No.55661-38-6 is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for glioblastomas.	price>
R-C-2862	PAMAM G0-Polyglutamic acid 50（4）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4532	PK11000 CAS No.38275-34-2	PK11000/CAS No.38275-34-2 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities.	price>
R-C-2863	PEG77(2)-PAMAM G0-Polyglutamic acid 50（2）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4533	Imifoplatin CAS No.1339960-28-9	Imifoplatin (PT-112)/CAS No.1339960-28-9 is a platinum-based agent belonging to the phosphaplatin family. Imifoplatin exhibits antineoplastic activity.	price>
R-C-2864	PEG77(1)-PAMAM G0-Polyglutamic acid50（3）	Dendrimer(PAMAM)Dendrimer)is a kind of high molecular dendrimer,which is a 3D three-dimensional mass material with a particle size of about 1-20nm.Its great feature is that it can simultaneously use the NH2 group on the surface and the internal pores to bond or coat different kinds of substances,which can be applied to drug release and biological detection.	price>
R-R-4534	Duocarmycin SA CAS No.130288-24-3	Duocarmycin SA/CAS No.130288-24-3 is an orally active antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro.	price>
R-C-2865	MAL-PEG2K-PLGA10K-citric acid	Poly(L-lactide-co-glycolide)-Polyethyleneglycol-Maleimide is a biodegradable functional amphiphilic block copolymer.The PEGhydrophilic is capped a maleimide group,and the PLGA hydrophobic blockterminates with a hydroxyl group.PLGA-PEG-MAL can self assemble into PLGA core/PEG shellpolymeric micelles.Maleimide on the micelle surface can conjugate withpeptides,antibodies,proteins and others which contain Thiol groups on thesurface.	price>
R-R-4535	Semustine CAS No.13909-09-6	Semustine/CAS No.13909-09-6 is a DNA alkylator, binds to DNA, and acts as a cancer chemotherapeutic agent.	price>
R-C-2866	HA-PLGA	Poly(lactic co glycolic acid)(PLGA)is a degradable functional polymer organic compound,which is randomly polymerized by two monomers-lactic acid and glycolic acid.It has good biocompatibility,non toxicity,good encapsulation and film-forming properties.With its unique molecular structure and physicochemical properties,hyaluronic acid shows a variety of important physiological functions in the body,such as lubricating joints,regulating the permeability of blood vessel wall,regulating protein and so on.	price>
R-R-4536	Pipobroman CAS No.54-91-1	Pipobroman/CAS No.54-91-1 is a bromide derivative of piperazine and acts as an alkylating agent. Pipobroman plays its role by inhibiting DNA and RNA polymerase or by reducing pyrimidine nucleotide incorporation into DNA. Pipobroman can be used for the cancer research, including polycythemia vera, myeloproliferative neoplasm, and AML et.al.	price>
R-C-2867	HA-SS-PLGA	Poly (lactic co glycolic acid)(PLGA)is a degradable functional polymer organic compound,which is randomly polymerized by two monomers-lactic acid and glycolic acid.It has good biocompatibility, non toxicity,good encapsulation and film-forming properties.With its unique molecular structure and physicochemical properties,hyaluronic acid shows a variety of important physiological functions in the body,such as lubricating joints,regulating the permeability of blood vessel wall,regulating protein and so on.	price>
R-R-4537	Phenanthriplatin CAS No.1416900-51-0	Phenanthriplatin/CAS No.1416900-51-0 is a monovalent platinum(II)-based complex with a large cytotoxicity against cancer cells.	price>
R-C-2868	Black phosphorus nano flake (Thickness 2-3nm)	Black phosphorus material can be used as an efficient photosensitizer,which can produce a large amount of singlet oxygen and can be used in photodynamic therapy.Black phosphorus itself has no toxicity to a variety of cells. After polyethylene glycol(PEG)is modified by electrostatic adsorption,the oxidation of black phosphorus can be effectively reduced and the stability can be significantly improved.It can not only improve the biocompatibility of the material,but also facilitate the further functional modification of the material.Black phosphorus nano flakes can produce local high heat under 808 nm laser irradiation.On the one hand,they can be used for photothermal therapy of tumors,on the other hand,they can also drive the release of drugs.	price>
R-R-4538	Bizelesin CAS No.129655-21-6	Bizelesin (NSC 615291; U-77779)/CAS No.129655-21-6 is an AT-specific DNA alkylating agent that can generate DNA interstrand crosslinks, effectively inhibit DNA replication, and has potential anticancer activity.	price>
R-C-2869	DSPE-PEG-VCAM1	Vascular cell adhesion protein 1(VCAM1)is also known as CD106,INCAM-100 and L1CAM,is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily.VCAM1/CD106 contains 7 Ig-like C2-type(immunoglobulin-like) domains.1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes.	price>

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