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Catalog name Description price
R-R-4506 Casein kinase 1o-IN-7 CAS No.764694-25-9 Casein kinase 1δ-IN-7 (compound 497)/CAS No.764694-25-9 is a Casein kinase 1δ inhibitor. Casein kinase 1δ-IN-7 can be used in the study of neurodegenerative disorders such as Alzheimer disease. price>
R-C-2807 SDZ NKT 343 CAS:180046-99-5 SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist that antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo. price>
R-R-4507 Casein kinase 1o-IN-3 CAS No.349438-77-3 Casein kinase 1δ-IN-3 (Compound 23a)/CAS No.349438-77-3 is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M. price>
R-C-2808 Almotriptan Malate CAS:181183-52-8 Almotriptan malate(Axert)is a selective 5-hydroxytryptamine1B/1D(5-HT1B/1D) receptor agonist,used for the treatment of Migraine attacks in adults. price>
R-R-4508 Cyclophosphamide CAS No.50-18-0 Cyclophosphamide/CAS No.50-18-0 is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. price>
R-C-2809 LY 344864 CAS:186544-26-3 LY344864 is a selective receptor agonist with an affinity of 6 nM(Ki)at the recently cloned 5-HT1F receptor. price>
R-R-4509 N-Nitroso-N-methylurea CAS No.684-93-5 N-Nitroso-N-methylurea (NMU;MNU;NMH)/CAS No.684-93-5 is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane. price>
R-C-2810 L 760735 CAS:188923-01-5 High affinity NK1 receptor antagonist(IC50=0.19nM at human NK1 receptors). Selective(>300-fold)over h-NK2 and h-NK3 receptors.Exhibits anxiolytic and antidepressant-like effects. price>
R-R-4510 Azoxymethane CAS No.25843-45-2 Azoxymethane/AOM/CAS No.25843-45-2 is a colon carcinogen which leads to the formation of DNA adducts. price>
R-C-2811 NGB 2904 CAS:189060-98-8 NGB 2904 is an orally active and selective dopamine(DA)D3 receptor antagonist.NGB 2904 can be used for the research of cocaine addiction. price>
R-R-4511 Phosphoramide mustard cyclohexanamine CAS No.1566-15-0 Phosphoramide mustard cyclohexanamine/CAS No.1566-15-0 is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage. price>
R-C-2812 Firocoxib CAS:189954-96-9 Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class,currently approved for use in dogs and horses. price>
R-R-4512 Calicheamicin CAS No.108212-75-5 Calicheamicin/CAS No.108212-75-5, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-2813 Bepotastine Besilate CAS:190786-44-8 Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist.Bepotastine besilate has the potential for allergic rhinitis,allergic conjunctivitis and urticaria/pruritus research. price>
R-R-4513 Lurbinectedin CAS No.497871-47-3 Lurbinectedin (PM01183)/CAS No.497871-47-3 is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively. price>
R-C-2814 LY 379268 CAS:191471-52-0 LY379268 is a potent,selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69nM(mGlu2)and 4.48nM(mGlu3).LY379268 has no activity on human mGlu 1a,4a,5a or 7a receptors.LY379268 has antioxidant and neuroprotective effects. price>
R-R-4514 SG3199 CAS No.1595275-71-0 SG3199/CAS No.1595275-71-0 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249). price>
R-R-4515 Tesirine CAS No.1595275-62-9 Tesirine (SG3249)/CAS No.1595275-62-9 is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity. price>
R-R-4516 Lomustine CAS No.13010-47-4 Lomustine (CCNU; NSC 79037)/CAS No.13010-47-4 is a DNA alkylating agent, with antitumor activity. price>
R-R-4517 Procarbazine Hydrochloride CAS No.366-70-1 Procarbazine Hydrochloride/CAS No.366-70-1 is an orally active alkylating agent, with anticancer activity. Procarbazine Hydrochloride can be used in Hodgkin disease research. price>