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Catalog	name	Description	price
R-R-4470	SCH-1473759 CAS No.1094069-99-4	SCH-1473759/CAS No.1094069-99-4 is an aurora inhibitor with IC50s of 4 and 13 nM for aurora A and B, respectively.	price>
R-C-2771	Cilomilast CAS:153259-65-5	Cilomilast(SB-207499)is a potent,selective and orally active inhibitor of Phosphodiesterase 4(PDE4),with IC50s of ~100 and 120nM for LPDE4 and HPDE4,respectively.Cilomilast shows selectivity for PDE4 over PDE1,PDE2,PDE3 and PDE5(IC50=74,65,>100,and 83µM,respectively).	price>
R-R-4471	AAPK-25 CAS No.2247919-28-2	AAPK-25/CAS No.2247919-28-2 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. AAPK-25 targets Aurora-A, -B, and -C with Kd values ranging from 23-289 nM, as well as PLK-1, -2, and -3 with Kd values ranging from 55-456 nM.	price>
R-C-2772	DMP 777 CAS:157341-41-8	DMP-777(L 694458)is a potent and orally active Leukocyte elastase(HLE)inhibitor.Oral dosing with DMP 777 caused a rapid increase in serum gastrin levels and severe hypochlorhydria.DMP 777 inhibited aminopyrine accumulation into rabbit parietal cells stimulated with either histamine or forskolin.	price>
R-R-4472	SJ3149 CAS No.3026986-17-1	SJ3149/CAS No.3026986-17-1 is a selective and potent degrader of CK1α protein in vitro and in vivo. SJ3149 has antitumor activity.	price>
R-C-2773	A-867744 CAS:1000279-69-5	A-867744 is a highly potent and selective type II positive allosteric modulator(PAM)of the alpha7 nicotinic acetylcholine receptors(nAChR)with an EC50 of 1.0μM.	price>
R-R-4473	DEG-77 CAS No.3032265-06-5	DEG-77/CAS No.3032265-06-5, a PROTAC based IKZF2 and CK1α degrader, possesses suitable pharmacokinetic properties, solubility, and selectivity for in vivo studies (t1/2=8h).	price>
R-C-2774	Desloratadine CAS:100643-71-8	Desloratadine(Sch34117)is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine.Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.	price>
R-R-4474	TMX-4116 CAS No.2766385-56-0	TMX-4116/CAS No.2766385-56-0 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma.	price>
R-C-2775	Rotundine CAS:483-14-7	Rotundine(L-tetrahydropalmatine,L-THP)is a selective dopamine D1 receptor antagonist with IC50 of 166nM.	price>
R-R-4475	Silmitasertib sodium salt CAS No.1309357-15-0	Silmitasertib sodium salt/CAS No.1309357-15-0 is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α.	price>
R-R-4476	TBB CAS No.17374-26-4	TBB/NSC 231634/Casein Kinase II Inhibitor I/CAS No.17374-26-4 is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.	price>
R-C-2776	Ebrotidine CAS:100981-43-9	Ebrotidine(FI 3542)is a competitive H2-receptor antagonist(Ki=27.5nM)with a potent antisecretory activity and evidenced gastroprotection.	price>
R-C-2777	CY 208-243 CAS：100999-26-6	CY 208-243 is a drug which acts as a dopamine agonist selective for the D1subtype.Unlike most D1-selective agonists,it shows efficacy in animal models of Parkinson is disease.	price>
R-R-4477	PF-4800567 CAS No.1188296-52-7	PF-4800567/CAS No.1188296-52-7 is a potent and selective inhibitor of casein kinase 1ϵ (CK1ϵ), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).	price>
R-C-2778	Talipexole CAS：101626-70-4	Talipexole(B-HT920)is a dopamine agonist that has been proposed as an antiparkinsonian agent.	price>
R-R-4478	DMAT CAS No.749234-11-5	DMAT/CK2 Inhibitor/Casein kinase II Inhibitor/CAS No.749234-11-5 is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.	price>
R-C-2779	ARN2966 CAS：102212-26-0	ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.	price>
R-R-4479	FPFT-2216 CAS No.2367619-87-0	FPFT-2216/CAS No.2367619-87-0, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). FPFT-2216 can be used for the research of cancer and inflammatory disease.	price>
R-C-2780	Otenzepad (AF-DX 116) CAS：102394-31-0	Otenzepad(AF-DX 116)is a selective and competitive M2 muscarinic acetylcholine receptor antagonist,with IC50 values of 640nM and 386nM for rabbit peripheral lung and rat heart,respectively.	price>

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