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Catalog	name	Description	price
R-C-2695	Lestaurtinib CAS：111358-88-4	Lestaurtinib(CEP-701;KT-5555)is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases.Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9,3 and less than 25nM,respectively.	price>
R-R-4395	FAUC 346 CAS No.474432-65-0	FAUC 346/CAS No.474432-65-0, a highly selective D3 partial agonist (EC50 = 1.5 nM).	price>
R-C-2696	MCB-613 CAS：1162656-22-5	MCB-613 is a potent Steroid Receptor Coactivator Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.MCB-613 can super-stimulate SRCs transcriptional activity.MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species(ROS).	price>
R-R-4396	Bromperidol (Standard) CAS No.10457-90-6	Bromperidol (Standard)/CAS No.10457-90-6 is the analytical standard of Bromperidol. This product is intended for research and analytical applications. Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin.	price>
R-C-2697	UNC 0224 CAS：1197196-48-7	UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6nM,an IC50 of 15nM and a Kd of 23nM.UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58nM.	price>
R-R-4397	L-DOPA-13C CAS No.586971-29-1	L-DOPA-13C/CAS No.586971-29-1 is the 13C labeled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain.	price>
R-C-2698	Tautomycetin CAS：119757-73-2	Tautomycetin is a potent and specifical PP1 inhibitor with the potential apoptosis-inducing activity.Tautomycetin inhibits purified PP1 and PP2A enzymes with IC50s of 1.6nM and 62nM,respectively.Tautomycetin is an antifungal antibiotic and has immunosuppressive effects in vivo.	price>
R-R-4398	Asimilobine CAS No.6871-21-2	Asimilobine/CAS No.6871-21-2 is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity.	price>
R-C-2699	AZD1208 CAS：1204144-28-4	AZD1208 is orally available,small molecule inhibitor of PIM kinases with potential antineoplastic activity.Pan-PIM kinase inhibitor AZD1208 inhibits the activities of PIM1,PIM2 and PIM3 serine/threonine kinases,which may result in the interruption of the G1/S phase cell cycle transition,thereby causing cell cycle arrest and inducing apoptosis in cells that overexpress PIMs.	price>
R-R-4399	PNU-177864 CAS No.250266-51-4	PNU-177864/CAS No.250266-51-4 is a potent, selective and orally active dopamine D3 receptor antagonist. PNU-177864 is structurally consistent with a cationic amphiphilic agent (CAD) and induces phospholipidosis in vivo. PNU-177864 antischizophrenic activity.	price>
R-C-2700	UNC0321 CAS：1238673-32-9	UNC0321 is the first G9a inhibitor with picomolar potency and the most potent G9a inhibitor to date.Protein lysine methyltransferase G9a,which catalyzes methylation of lysine 9 of histone H3(H3K9)and lysine 373(K373)of p53,is overexpressed in human cancers.	price>
R-R-4400	NPEC-caged-dopamine CAS No.1257326-23-0	NPEC-caged-dopamine/CAS No.1257326-23-0 is a caged version of dopamine. NPEC-caged-Dopamine was used by applying focal photolysis with UV light (360 nm) to releases dopamine, which leads to D1 receptor activation.	price>
R-C-2701	GSK 525768A CAS：1260530-25-3	GSK 525768A is the enantiomer compound of GSK 525762A,which is a potent small molecule inhibitor that disrupt the function of the BET family of bromodomains (Brd2,Brd3,and Brd4);GSK 525768A has NO activity towards BET.	price>
R-R-4401	Timiperone CAS No.57648-21-2	Timiperone/CAS No.57648-21-2 has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits stereotyped behaviour. Timiperone can be used for research of schizophrenia.	price>
R-C-2702	GSK1324726A (I-BET726) CAS：1300031-52-0	GSK1324726A is a novel,potent,and selective inhibitor of BET proteins with high affinity to BRD2(IC50=41nM),BRD3(IC50=31nM),and BRD4(IC50=22nM).	price>
R-R-4402	Pramipexole-d5 dihydrochloride CAS No.1217601-58-5	Pramipexole-d5 (dihydrochloride)/CAS No.1217601-58-5 is deuterium labeled Pramipexole (dihydrochloride). Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively.	price>
R-C-2703	Sephin1 CAS:951441-04-6	Sephin1 is a selective inhibitor of a holophosphatase.Sephin1 selectively bound and inhibited the stress-induced PPP1R15A,but not the related and constitutive PPP1R15B,to prolong the benefit of an adaptive phospho-signaling pathway, protecting cells from otherwise lethal protein misfolding stress.	price>
R-R-4403	Dopamine D2 receptor agonist-3 CAS No.1257326-24-1	Dopamine D2 receptor agonist-3 (compound 3)/CAS No.1257326-24-1 is a selective D2 receptor partial agonist and Dopamine D3 receptor antagonist (with pEC50 of 8.3 and <5.5 respectively).	price>
R-C-2704	Cercosporamide CAS：131436-22-1	Cercosporamide,an usnic amide,was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2(Mnk2;IC50=11 nM),JAK3(IC50=31),and Mnk1(IC50=116nM).	price>
R-R-4404	Ropinirole-d7 hydrochloride CAS No.1261396-31-9	Ropinirole-d7 (hydrochloride)/CAS No.1261396-31-9 is the deuterium labeled Ropinirole hydrochloride[1]. Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors.	price>

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