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Catalog	name	Description	price
R-C-2760	PACOCF3 CAS：141022-99-3	Phospholipase A2 inhibitor.	price>
R-R-4460	DB0614 CAS No.2769753-47-9	DB0614 (Example 21)/CAS No.2769753-47-9 is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity.	price>
R-C-2761	YM 26734 CAS：144337-18-8	YM-26734 is an inhibitor of rabbit platelet sPLA2.YM-26734 has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema.	price>
R-R-4461	ENMD-2076 Tartrate CAS No.1453868-32-0	ENMD-2076 Tartrate/CAS No.1453868-32-0 is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.	price>
R-C-2762	GSK 2837808A CAS：1445879-21-9	GSK2837808A is a potent,selective lactate dehydrogenase A(LDHA)inhibitor(IC50 values are 1.9 and 14nM for LDHA and LDHB respectively).	price>
R-R-4462	CCT241736 CAS No.1402709-93-6	CCT241736/CAS No.1402709-93-6 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).	price>
R-C-2763	DGAT1-IN-1 CAS：1449779-49-0	DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of<10nM(cell lysate from Hep3B cells overexpressing human DGAT1).	price>
R-R-4463	Aurora kinase inhibitor-3 CAS No.879127-16-9	Aurora kinase inhibitor-3/CAS No.879127-16-9 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket.	price>
R-C-2764	Pralatrexate (NSC 754230) CAS：146464-95-1	Pralatrexate(NSC 754230)is an antifolate, and structurally a folate analog.Its IC50 is<300nM in some cell lines.Pralatrexate induces tumor cell apoptosis.	price>
R-R-4464	dAURK-4 hydrochloride	dAURK-4 hydrochloride, an Alisertib derivative, is a potent and selective AURKA (Aurora A) degrader. dAURK-4 hydrochloride has anticancer effects.	price>
R-C-2765	Pitavastatin(NK-104) CAS:147526-32-7	Pitavastatin Calcium(NK-104,P-872441,itavastatin,nisvastatin),a novel member of the medication class of statins,is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor.Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation.	price>
R-R-4465	AKI603 CAS No.1432515-73-5	AKI603/CAS No.1432515-73-5 is an inhibitor of Aurora kinase A (AurA), with an IC50 of 12.3 nM. AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells.	price>
R-R-4466	Tinengotinib CAS No.2230490-29-4	Tinengotinib/CAS No.2230490-29-4 is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase. Tinengotinib has the potential for the research of these kinase abnormalities diseases mediated, especially cancer-related diseases (extracted from patent WO2018108079A1).	price>
R-C-2767	YM 511 CAS:148869-05-0	Orally active,potent aromatase(CYP19)inhibitor(IC50 values are 0.4 and 0.12nM at rat ovary and human placenta cells respectively)that only weakly inhibits the synthesis of other steroid hormones.Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro(IC50=0.13nM).	price>
R-R-4467	Aurora kinase inhibitor-8 CAS No.2133001-88-2	Aurora kinase inhibitor-8/CAS No.2133001-88-2 is a highly selective inhibitor of the Aurora kinases.	price>
R-C-2768	PDN01791 CAS:149301-79-1	PDN01791（Arachidonyl Trifluoromethyl Ketone）is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group.It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s.	price>
R-R-4468	TC-A 2317 hydrochloride CAS No.1245907-03-2	TC-A 2317 hydrochloride/CAS No.1245907-03-2 is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity.	price>
R-C-2769	MOG (35-55) CAS:149635-73-4	Myelin oligodendrocyte glycoprotein(MOG)35-55 is a minor component of CNS myelin.Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination,common to the manifestations of multiple sclerosis.Induces strong T and B cell responses and is highly encephalitogenic.	price>
R-R-4469	Aurora Kinases-IN-3 CAS No.2840558-83-8	Aurora Kinases-IN-3 (Compound 15a)/CAS No.2840558-83-8 is an orally active AURKB inhibitor that elicits an AURKB-suppressive activity by disrupting the mitotic localization of AURKB, rather than inhibiting its phosphorylation of H3 at Ser10.	price>
R-C-2770	JJKK 048 CAS:1515855-97-6	JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase(MAGL).	price>

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