Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-C-2646	Z-WEHD-FMK CAS:210345-00-9	Z-WEHD-FMK is a potent,cell-permeable and irreversible caspase-1/5 inhibitor.Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6μM).Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis.	price>
R-R-4346	Acetophenazine dimaleate CAS No.5714-00-1	Acetophenazine dimaleate/CAS No.5714-00-1, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for researching psychotic disorders such as schizophrenia and anxious depression.	price>
R-C-2647	Ac-LEHD-AFC	Ac-LEHD-AFC,fluorogenic caspase substrate.Analog of the caspase-9 substrate, LEHD-AFC.	price>
R-R-4347	UCM-1306 CAS No.2258608-78-3	UCM-1306/CAS No.2258608-78-3 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinson disease (PD).	price>
R-C-2648	Gambogic acid CAS:2752-65-0	Gambogic Acid(Beta-Guttiferrin)is derived from the gamboges resin of the tree Garcinia hanburyi.Gambogic Acid (Beta-Guttiferrin)inhibits Bcl-XL,Bcl-2,Bcl-W,Bcl-B,Bfl-1 and Mcl-1 with IC50s of 1.47μM,1.21μM,2.02 μM,0.66μM,1.06μM and 0.79μM.	price>
R-R-4348	L-745870 hydrochloride CAS No.1173023-36-3	L-745870 hydrochloride/CAS No.1173023-36-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.	price>
R-R-4349	Trimethobenzamide hydrochloride CAS No.554-92-7	Trimethobenzamide hydrochloride/CAS No.554-92-7 is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.	price>
R-C-2650	Necrostatin-1 CAS:4311-88-0	Necrostatin-1(Nec-1)is a specific RIP1(RIPK1)inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.	price>
R-R-4350	ML417 CAS No.1386162-69-1	ML417/CAS No.1386162-69-1 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons.	price>
R-C-2651	Pifithrin-β CAS:60477-34-1	Pifithrin-β(PFT β)is a potent p53 inhibitor with an IC50 of 23μM.	price>
R-R-4351	SKF 77434 hydrobromide CAS No.300561-58-4	SKF 77434 hydrobromide/CAS No.300561-58-4 is a selective dopamine D1 receptor partial agonist. SKF 77434 hydrobromide has the potential to study cocaine addiction.	price>
R-C-2652	CAY10603 CAS:1045792-66-2	CAY10603(BML-281)is a potent and selective HDAC6 inhibitor,with an IC50 of 2 pM;CAY10603(BML-281)also inhibits HDAC1,HDAC2,HDAC3,HDAC8,HDAC10,with IC50s of 271,252,0.42,6851,90.7nM.	price>
R-R-4352	L-Stepholidine CAS No.16562-13-3	L-Stepholidine (Stepholidine)/CAS No.16562-13-3 exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction.	price>
R-C-2653	Mupirocin CAS:12650-69-0	Mupirocin(BRL-4910A)is an orally active antibiotic isolated from Pseudomonas fluorescens.Mupirocin(BRL-4910A)apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA,thereby inhibiting bacterial protein and RNA synthesis.	price>
R-R-4353	MLS1082 CAS No.883958-36-9	MLS1082/CAS No.883958-36-9 is a pyrimidone-based D1-like dopamine receptor positive allosteric modulator, with an EC50 of 123 nM for DA-stimulated G protein signaling.	price>
R-C-2654	Satraplatin CAS:129580-63-8	Satraplatin(JM216,BMS182751)is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy.It has not yet received approval from the U.S.Food and Drug Administration.First mentioned in the medical literature in 1993,satraplatin is the first orally active platinum-based chemotherapeutic drug;other available platinum analogues-cisplatin,carboplatin,and oxaliplatin-must be given intravenously.	price>
R-R-4354	Molindone hydrochloride CAS No.15622-65-8	Molindone hydrochloride (EN-1733A)/CAS No.15622-65-8 is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.	price>
R-C-2655	INNO-206 CAS:1361644-26-9	Aldoxorubicin(INNO-206)is an albumin-binding prodrug of Doxorubicin(DNA topoisomerase II inhibitor),which is released from albumin under acidic conditions.Aldoxorubicin(INNO-206)has potent antitumor activities in various cancer cell lines and in murine tumor models.	price>
R-R-4355	ABT-724 trihydrochloride CAS No.587870-77-7	ABT-724 trihydrochloride/CAS No.587870-77-7 is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.	price>
R-C-2656	NVP-TNKS656 CAS:1419949-20-4	NVP-TNKS656 is a highly potent,selective,and orally active TNKS2 inhibitor with IC50 of 6nM,and is>300 fold selectivity against PARP1 and PARP2.	price>

640641642643644645 646647648649650