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Catalog	name	Description	price
R-C-2636	A 77-01 CAS:607737-87-1	A 77-01 is a potent inhibitor of transforming growth factor(TGF)-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.	price>
R-R-4336	Rimcazole dihydrochloride CAS No.75859-03-9	Rimcazole (BW 234U) dihydrochloride/CAS No.75859-03-9 is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can reduce locomotor activity and sensitization. Rimcazole dihydrochloride also can be used for the research of cancer.	price>
R-C-2637	Rottlerin CAS:82-08-6	Rottlerin is an angiogenesis inhibitor and an inhibitor of protein kinase Cdelta (PKCdelta)and calmodulin kinase III.Rottlerin induces cyclooxygenase-2 upregulation through an ATF4 and reactive oxygen species-independent pathway in HEI-OC1 cells.Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells.	price>
R-R-4337	SKF 83959 hydrobromide CAS No.67287-95-0	SKF83959 hydrobromide/CAS No.67287-95-0 is a potent and selective dopamine D1-like receptor partial agonist. SKF83959 hydrobromide Ki values for rat D1, D5, D2 and D3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction.	price>
R-C-2638	Bryostatin 1 CAS:83314-01-6	Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system(CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07nM and 0.45nM,respectively.	price>
R-R-4338	PF-06256142 CAS No.1609583-14-3	PF-06256142/CAS No.1609583-14-3 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively.	price>
R-C-2639	ZIP CAS:863987-12-6	ZIP is a selective peptide inhibitor of PKMζ.ZIP injections can block the impairment in morphine conditioned place preference induced.	price>
R-R-4339	Tavapadon CAS No.1643489-24-0	Tavapadon (PF-06649751)/CAS No.1643489-24-0 is an orally active and highly selective dopamine D1/D5 receptor partial agonist.	price>
R-C-2640	PPY A CAS:875634-01-8	PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinases(IC50 values are 9 and 20nM,respectively).Inhibits growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene.	price>
R-R-4340	Mesdopetam hemitartrate CAS No.2562346-14-7	Mesdopetam (IRL790) hemitartrate/CAS No.2562346-14-7 is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease.	price>
R-C-2641	Bryostatin 2 CAS:87745-28-6	Bryostatin 2 is a protein kinase C(PKC)activator.	price>
R-R-4341	Dopamine D2 receptor antagonist-1 CAS No.1055411-77-2	Dopamine D2 receptor antagonist-1/CAS No.1055411-77-2 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity.	price>
R-C-2642	A 83-01 CAS: 909910-43-6	A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase,type I nodal receptor ALK4 and type I nodal receptor ALK7,with IC50s of 12nM,45nM and 7.5nM against the transcription induced by ALK5,ALK4 and ALK7,respectively.	price>
R-R-4342	Propionylpromazine hydrochloride CAS No.7681-67-6	Propionylpromazine hydrochloride (Propiopromazine hydrochloride)/CAS No.7681-67-6, a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease.	price>
R-C-2643	SPK-601 CAS:1096687-52-3	SPK-601(LMV-601)is an inhibitor of the phosphatidylcholine-specific phospholipase C(PC-PLC).SPK-601 also can be used as an antimicrobial agent.	price>
R-R-4343	Quinelorane dihydrochloride CAS No.97548-97-5	Quinelorane dihydrochloride (LY163502)/CAS No.97548-97-5 is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research.	price>
R-C-2644	Z-DEVD-FMK CAS:210344-95-9	Z-DEVD-FMK(Caspase-3 Inhibitor)is a specific,irreversible Caspase-3 inhibitor,and also shows potent inhibition on caspase-6,caspase-7,caspase-8, and caspase-10.	price>
R-R-4344	(Rac)-PF-06256142 CAS No.1609580-97-3	(Rac)-PF-06256142/CAS No.1609580-97-3 is the less effective enantiomer of PF-06256142 (HY-119943). (Rac)-PF-06256142 is an agonist of D1 receptor, with an EC50 of 107 nM.	price>
R-C-2645	Z-IETD-FMK CAS:210344-98-2	Z-IETD-FMK(Z-IE(OMe)TD(OMe)-FMK)is a selective and cell permeable caspase-8 inhibitor.Z-IETD-FMK is also a granzyme B inhibitor.	price>
R-R-4345	Carmoxirole hydrochloride CAS No.115092-85-8	Carmoxirole hydrochloride (EMD 45609 hydrochloride)/CAS No.115092-85-8 is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo.	price>

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