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Catalog	name	Description	price
R-C-2626	SC-9 cas:102649-78-5	SC-9 is a protein kinase C(PKC)activator in the presence of Ca2+.	price>
R-R-4326	Pericyazine CAS No.2622-26-6	Pericyazine (Propericiazine)/CAS No.2622-26-6 is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects.	price>
R-C-2627	PD 180970 CAS:287204-45-9	PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8nM and 50nM, respectively.	price>
R-R-4327	Eticlopride hydrochloride CAS No.97612-24-3	Eticlopride hydrochloride/CAS No.97612-24-3, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent.	price>
R-C-2628	Narciclasine CAS:29477-83-6	Narciclasine is a plant growth modulator.Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway,greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.	price>
R-R-4328	Azaperone CAS No.1649-18-9	Azaperone (R-1929)/CAS No.1649-18-9 acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.	price>
R-C-2629	Chelerythrine CAS: 34316-15-9	Chelerythrine is a natural alkaloid,acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist,with an IC50 of 0.7μM.Chelerythrine has antitumor,antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5μM and displaces Bax from BclXL.Chelerythrine triggers apoptosis and autophagy.	price>
R-R-4329	(±)-Levomepromazine-d6 CAS No.1189805-51-3	(±)-Levomepromazine-d6/CAS No.1189805-51-3 is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.	price>
R-C-2630	Saracatinib (AZD0530) CAS:379231-04-6	Saracatinib(AZD0530)is a potent Src family inhibitor with IC50s of 2.7 to 11nM for c-Src,Lck,c-YES,Lyn,Fyn,Fgr,and Blk.Saracatinib shows high selectivity over other tyrosine kinases.	price>
R-R-4330	UCSF924 CAS No.1434515-70-4	UCSF924/CAS No.1434515-70-4 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has a high-affinity with a Ki value of 3 nM for DRD4 and shows no measurable affinity for D2, D3 or the F261V/L328F D4 mutant. UCSF924 is a 7.4-fold bias toward arrestin over Gαi/o signaling, referenced to quinpirole.	price>
R-C-2631	Sotrastaurin (AEB071) CAS:425637-18-9	Sotrastaurin(AEB071)is a potent and orally-active pan-PKC inhibitor,with Kis of 0.22 nM,0.64nM,0.95nM,1.8nM,2.1nM and 3.2nM for PKCθ,PKCβ,PKCα,PKCη,PKCδ and PKCε,respectively.	price>
R-R-4331	SKF 83959 CAS No.80751-85-5	SKF83959/CAS No.80751-85-5 is a potent and selective dopamine D1-like receptor partial agonist. SKF83959 Ki values for rat D1, D5, D2 and D3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction.	price>
R-C-2632	RepSox (E-616452) CAS:446859-33-2	RepSox(E-616452)is a potent and selective of the TGFβR-1/ALK5 inhibitor which inhibits ALK5 autophosphorylation with an IC50 of 4nM.	price>
R-R-4332	Roxindole hydrochloride CAS No.108050-82-4	Roxindole hydrochloride (EMD 38362)/CAS No.108050-82-4, an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities.	price>
R-C-2633	Epicatechin CAS:490-46-0	Epicatechin is a flavan-3-ol,a type of natural phenol and antioxidant.It is a plant secondary metabolite.The name of the catechin chemical family derives from catechu,which is the tannic juice or boiled extract of Mimosa catechu (Acacia catechu L.f).	price>
R-R-4333	3-O-Methyldopa-d3 CAS No.586954-09-8	3-O-Methyldopa-d3/CAS No.586954-09-8 is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.	price>
R-C-2634	Dequalinium Chloride CAS:522-51-0	Dequalinium chloride is a topical bacteriostat that is available as various salts.It is used in wound dressings and mouth infections and may also have antifungal action,but may cause skin ulceration.	price>
R-R-4334	UNC9995 CAS No.1354030-52-6	UNC9995/CAS No.1354030-52-6 is a β-arrestin2-biased agonist of dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thus prevents neuronal degeneration. Futhermore, UNC9995 activates the Drd2/β-arrestin2 signaling to prevent inflammation-related genes transcription-induced by JAK/STAT3. UNC9995 improves depressive behavior in mouse model, and improves astrocytes dysfunctions.	price>
R-C-2635	Pirfenidone CAS:53179-13-8	Pirfenidone(AMR69)is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines.Pirfenidone also has anti-inflammatory activities.	price>
R-R-4335	SKF 83822 CAS No.74115-08-5	SKF 83822/CAS No.74115-08-5 is an atypical agonist of dopamine D1 receptor. SKF 83822 activates adenylyl cyclase (AC), but not phospholipase C (PLC). SKF 83822 is also proved to stimulate AC via cAMP production. SKF 83822 can be used for research of schizophrenia.	price>

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