Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-4399	PNU-177864 CAS No.250266-51-4	PNU-177864/CAS No.250266-51-4 is a potent, selective and orally active dopamine D3 receptor antagonist. PNU-177864 is structurally consistent with a cationic amphiphilic agent (CAD) and induces phospholipidosis in vivo. PNU-177864 antischizophrenic activity.	price>
R-C-2700	UNC0321 CAS：1238673-32-9	UNC0321 is the first G9a inhibitor with picomolar potency and the most potent G9a inhibitor to date.Protein lysine methyltransferase G9a,which catalyzes methylation of lysine 9 of histone H3(H3K9)and lysine 373(K373)of p53,is overexpressed in human cancers.	price>
R-R-4400	NPEC-caged-dopamine CAS No.1257326-23-0	NPEC-caged-dopamine/CAS No.1257326-23-0 is a caged version of dopamine. NPEC-caged-Dopamine was used by applying focal photolysis with UV light (360 nm) to releases dopamine, which leads to D1 receptor activation.	price>
R-C-2701	GSK 525768A CAS：1260530-25-3	GSK 525768A is the enantiomer compound of GSK 525762A,which is a potent small molecule inhibitor that disrupt the function of the BET family of bromodomains (Brd2,Brd3,and Brd4);GSK 525768A has NO activity towards BET.	price>
R-R-4401	Timiperone CAS No.57648-21-2	Timiperone/CAS No.57648-21-2 has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits stereotyped behaviour. Timiperone can be used for research of schizophrenia.	price>
R-C-2702	GSK1324726A (I-BET726) CAS：1300031-52-0	GSK1324726A is a novel,potent,and selective inhibitor of BET proteins with high affinity to BRD2(IC50=41nM),BRD3(IC50=31nM),and BRD4(IC50=22nM).	price>
R-R-4402	Pramipexole-d5 dihydrochloride CAS No.1217601-58-5	Pramipexole-d5 (dihydrochloride)/CAS No.1217601-58-5 is deuterium labeled Pramipexole (dihydrochloride). Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively.	price>
R-C-2703	Sephin1 CAS:951441-04-6	Sephin1 is a selective inhibitor of a holophosphatase.Sephin1 selectively bound and inhibited the stress-induced PPP1R15A,but not the related and constitutive PPP1R15B,to prolong the benefit of an adaptive phospho-signaling pathway, protecting cells from otherwise lethal protein misfolding stress.	price>
R-R-4403	Dopamine D2 receptor agonist-3 CAS No.1257326-24-1	Dopamine D2 receptor agonist-3 (compound 3)/CAS No.1257326-24-1 is a selective D2 receptor partial agonist and Dopamine D3 receptor antagonist (with pEC50 of 8.3 and <5.5 respectively).	price>
R-C-2704	Cercosporamide CAS：131436-22-1	Cercosporamide,an usnic amide,was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2(Mnk2;IC50=11 nM),JAK3(IC50=31),and Mnk1(IC50=116nM).	price>
R-R-4404	Ropinirole-d7 hydrochloride CAS No.1261396-31-9	Ropinirole-d7 (hydrochloride)/CAS No.1261396-31-9 is the deuterium labeled Ropinirole hydrochloride[1]. Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors.	price>
R-C-2705	EPZ004777 CAS：1338466-77-5	EPZ004777 is a potent,selective DOT1L inhibitor with IC50 of 0.4nM in a cell-free assay and demonstrates>1,200-fold selectivity for DOT1L over all other tested PMTs.EPZ004777 induces apoptosis.	price>
R-R-4405	(E/Z)-Chlorprothixene-d6 hydrochloride CAS No.1246832-91-6	(E/Z)-Chlorprothixene-d6 hydrochloride/CAS No.1246832-91-6 is the deuterium labeled (E/Z)-Chlorprothixene hydrochloride.	price>
R-C-2706	ML 228 CAS：1357171-62-0	ML228(CID-46742353)is a potent the Hypoxia Inducible Factor(HIF)pathway activator with EC50 of 1μM.ML228 potently activates HIF in vitro as well as its downstream target VEGF.	price>
R-R-4406	Fluphenazine-d8 dihydrochloride	Fluphenazine-d8 (dihydrochloride) is the deuterium labeled Fluphenazine dihydrochloride. Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.	price>
R-C-2707	OG-L002 CAS:1357302-64-7	OG-L002 is a potent and highly selective LSD1 inhibitor with an IC50 of 0.02 μM.OG-L002 is a potent monoamine oxidases(MAO)inhibitor with IC50s of 1.38μM and 0.72μM for MAO-A and MAO-B,respectively.OG-L002 potently inhibits the expression of HSV IE genes.	price>
R-R-4407	Bromperidol hydrochloride CAS No.59453-24-6	Bromperidol (R-11333) hydrochloride/CAS No.59453-24-6 possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill Mycobacteria in a synergistic manner with Spectinomycin.	price>
R-C-2708	CBB1003 CAS:1379573-88-2	CBB1003 is a novel histone demethylase LSD1 inhibitor with IC50 of 10.54uM.	price>
R-R-4408	PG01037 dihydrochloride CAS No.675599-62-9	PG01037 (dihydrochloride)/CAS No.675599-62-9 is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.	price>
R-C-2709	CBB1007 CAS:1379573-92-8	CBB1007 is a cell-permeable amidino-guanidinium compound that acts as a potent,reversible and substrate competitive LSD1 selective inhibitor (IC50=5.27μM for hLSD1).	price>

638639640641642643 644645646647648