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Catalog	name	Description	price
R-R-4340	Mesdopetam hemitartrate CAS No.2562346-14-7	Mesdopetam (IRL790) hemitartrate/CAS No.2562346-14-7 is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease.	price>
R-C-2641	Bryostatin 2 CAS:87745-28-6	Bryostatin 2 is a protein kinase C(PKC)activator.	price>
R-R-4341	Dopamine D2 receptor antagonist-1 CAS No.1055411-77-2	Dopamine D2 receptor antagonist-1/CAS No.1055411-77-2 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity.	price>
R-C-2642	A 83-01 CAS: 909910-43-6	A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase,type I nodal receptor ALK4 and type I nodal receptor ALK7,with IC50s of 12nM,45nM and 7.5nM against the transcription induced by ALK5,ALK4 and ALK7,respectively.	price>
R-R-4342	Propionylpromazine hydrochloride CAS No.7681-67-6	Propionylpromazine hydrochloride (Propiopromazine hydrochloride)/CAS No.7681-67-6, a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease.	price>
R-C-2643	SPK-601 CAS:1096687-52-3	SPK-601(LMV-601)is an inhibitor of the phosphatidylcholine-specific phospholipase C(PC-PLC).SPK-601 also can be used as an antimicrobial agent.	price>
R-R-4343	Quinelorane dihydrochloride CAS No.97548-97-5	Quinelorane dihydrochloride (LY163502)/CAS No.97548-97-5 is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research.	price>
R-C-2644	Z-DEVD-FMK CAS:210344-95-9	Z-DEVD-FMK(Caspase-3 Inhibitor)is a specific,irreversible Caspase-3 inhibitor,and also shows potent inhibition on caspase-6,caspase-7,caspase-8, and caspase-10.	price>
R-R-4344	(Rac)-PF-06256142 CAS No.1609580-97-3	(Rac)-PF-06256142/CAS No.1609580-97-3 is the less effective enantiomer of PF-06256142 (HY-119943). (Rac)-PF-06256142 is an agonist of D1 receptor, with an EC50 of 107 nM.	price>
R-C-2645	Z-IETD-FMK CAS:210344-98-2	Z-IETD-FMK(Z-IE(OMe)TD(OMe)-FMK)is a selective and cell permeable caspase-8 inhibitor.Z-IETD-FMK is also a granzyme B inhibitor.	price>
R-R-4345	Carmoxirole hydrochloride CAS No.115092-85-8	Carmoxirole hydrochloride (EMD 45609 hydrochloride)/CAS No.115092-85-8 is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo.	price>
R-C-2646	Z-WEHD-FMK CAS:210345-00-9	Z-WEHD-FMK is a potent,cell-permeable and irreversible caspase-1/5 inhibitor.Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6μM).Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis.	price>
R-R-4346	Acetophenazine dimaleate CAS No.5714-00-1	Acetophenazine dimaleate/CAS No.5714-00-1, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for researching psychotic disorders such as schizophrenia and anxious depression.	price>
R-C-2647	Ac-LEHD-AFC	Ac-LEHD-AFC,fluorogenic caspase substrate.Analog of the caspase-9 substrate, LEHD-AFC.	price>
R-R-4347	UCM-1306 CAS No.2258608-78-3	UCM-1306/CAS No.2258608-78-3 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinson disease (PD).	price>
R-C-2648	Gambogic acid CAS:2752-65-0	Gambogic Acid(Beta-Guttiferrin)is derived from the gamboges resin of the tree Garcinia hanburyi.Gambogic Acid (Beta-Guttiferrin)inhibits Bcl-XL,Bcl-2,Bcl-W,Bcl-B,Bfl-1 and Mcl-1 with IC50s of 1.47μM,1.21μM,2.02 μM,0.66μM,1.06μM and 0.79μM.	price>
R-R-4348	L-745870 hydrochloride CAS No.1173023-36-3	L-745870 hydrochloride/CAS No.1173023-36-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.	price>
R-R-4349	Trimethobenzamide hydrochloride CAS No.554-92-7	Trimethobenzamide hydrochloride/CAS No.554-92-7 is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.	price>
R-C-2650	Necrostatin-1 CAS:4311-88-0	Necrostatin-1(Nec-1)is a specific RIP1(RIPK1)inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.	price>
R-R-4350	ML417 CAS No.1386162-69-1	ML417/CAS No.1386162-69-1 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons.	price>

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