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Catalog	name	Description	price
R-R-4159	Zelnecirnon CAS No.2366152-15-8	Zelnecirnon (RPT193)/CAS No.2366152-15-8 is an orally active inhibitor of CCR4, blocks the recruitment of Th2 inflammatory immune cells into inflamed tissues. Zelnecirnon can be used for allergic inflammation in atopic dermatitis, asthma, and other diseases research.	price>
R-C-2460	Varenicline Tartrate (CP 526555-18) CAS：375815-87-5	Varenicline Tartrate(CP 526555;Champix)is a nicotinic receptor partial agonist; it stimulates nicotine receptors more weakly than nicotine itself does.	price>
R-R-4160	CCR6 antagonist 1 CAS No.588674-64-0	CCR6 antagonist 1/CAS No.588674-64-0 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).	price>
R-C-2461	Bethanechol chloride CAS：590-63-6	Bethanechol chloride(Carbamyl-β-methylcholine chloride),a parasympathomimetic agent,is a mAChR agonist that exerts its effects via directly stimulating the mAChR(M1,M2,M3,M4,and M5)of the parasympathetic nervous system.	price>
R-R-4161	CCR6 inhibitor 1 CAS No.2437547-04-9	CCR6 inhibitor 1/CAS No.2437547-04-9 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.	price>
R-C-2462	Pilocarpine HCl CAS：54-71-7	Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor(M3 muscarinic receptor)agonist.	price>
R-R-4162	AZD2098 CAS No.566203-88-1	AZD2098/CAS No.566203-88-1 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.	price>
R-C-2463	Nitenpyram CAS:150824-47-8	Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor(nAChR)agonist with an IC50 of 14nM.Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.	price>
R-R-4163	ZK756326 dihydrochloride CAS No.1780259-94-0	ZK756326 dihydrochloride/CAS No.1780259-94-0 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.	price>
R-C-2464	LY2119620 CAS:886047-22-9	LY2119620 is a positive allosteric modulator of the M2 and M4 muscarinic acetylcholine receptors(mAChRs).	price>
R-R-4164	AZ084 CAS No.929300-19-6	AZ084/CAS No.929300-19-6 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer.	price>
R-C-2465	Cytisine CAS:485-35-8	Cytisine(Baphitoxine,Sophorine)is a nicotinic acetylcholine receptor agonist.	price>
R-R-4165	BX471 hydrochloride CAS No.288262-96-4	BX471 hydrochloride (ZK-811752 hydrochloride)/CAS No.288262-96-4 is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.	price>
R-C-2466	Choline Chloride CAS:67-48-1	Choline chloride is a quaternary ammonium salt used as an additive for animal feed.It is important as a precursor of acetylcholine,as a methyl donor in various metabolic processes,and in lipid metabolism.	price>
R-R-4166	R243 CAS No.688352-84-3	R243/CAS No.688352-84-3 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects.	price>
R-C-2467	Cevimeline CAS:153504-70-2	Cevimeline(AF-102B)is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist.Cevimeline stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia.Cevimeline can cross the blood-brain barrier(BBB).	price>
R-R-4167	GW 766994 CAS No.408303-43-5	GW 766994 (GW 994)/CAS No.408303-43-5 is a chemokine receptor-3 (CCR3) antagonist that is orally active and specific. GW 766994 has the potential for research into asthma and eosinophilic bronchitis.	price>
R-C-2468	Clozapine N-oxide CAS:34233-69-7	Clozapine N-oxide is a metabolite of clozapine(GLXC-06516),activating human muscarinic designer receptors(DREADDs)and suppressing food intake.	price>
R-R-4168	C-021 CAS No.864289-85-0	C-021/CAS No.864289-85-0 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.	price>
R-C-2469	Trospium chloride CAS:10405-02-4	Trospium chloride is an orally active,specific and competitive antagonist of muscarinic cholinergic receptors(mAChRs),with antimuscarinic activity.Trospium chloride binds to muscarinic receptors M1,M2 and M3 with high affinity,but not nicotinic,cholinergic receptors.	price>

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