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Catalog	name	Description	price
R-R-4320	GSK598809 CAS No.863680-45-9	GSK598809/CAS No.863680-45-9 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9.	price>
R-C-2621	LDN-212854 CAS:1432597-26-6	LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity for BMP versus the TGF-β type I receptors;possesses a bias towards ALK2(IC50=1.3nM)versus ALK1 and ALK3 compared to other inhibitors.	price>
R-R-4321	L-745870 CAS No.158985-00-3	L-745870/CAS No.158985-00-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.	price>
R-C-2622	CGP 53353 CAS:145915-60-2	Selective inhibitor of PKCβII(IC50 values are 0.41 and 3.8μM for PKCβII and PKCβI respectively).Also inhibits prionogenic Sup35 fibrillization (IC50~ 3.4μM)and inhibits de novo Aβ42 assembly in vitro.	price>
R-R-4322	Tiapride hydrochloride CAS No.51012-33-0	Tiapride hydrochloride/CAS No.51012-33-0 is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent.	price>
R-C-2623	Y-27632 CAS:146986-50-7	Y-27632 is an orally active,ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300nM,respectively.Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells.Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells.	price>
R-R-4323	MLS1547 CAS No.315698-36-3	MLS1547/CAS No.315698-36-3 is a highly efficacious G protein-biased dopamine D2 receptor (D2R) agonist (Ki=1.2 μM). MLS1547 stimulates D2R G protein-mediated signaling (EC50=0.37 μM in a calcium mobilization assay). MLS1547 acts as an antagonist for dopamine (DA)-stimulated β-arrestin recruitment to the D2R (IC50=9.9 μM).	price>
R-C-2624	Adaphostin CAS:241127-58-2	Adaphostin is a novel activator of Fas-mediated death pathway in Bcr/Abl-positive leukaemia.	price>
R-R-4324	Halopemide CAS No.59831-65-1	Halopemide/CAS No.59831-65-1 is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent.	price>
R-C-2625	FR 236924 CAS:28399-31-7	Selective PKCεactivator that displays>7-fold selectivity over other PKC isozymes.Stimulates glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo.	price>
R-R-4325	(+)-PD 128907 hydrochloride CAS No.300576-59-4	(+)-PD 128907 hydrochloride/CAS No.300576-59-4 is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84 nM for human and rat D3 receptors, 179, 770 n M for human and rat D3 receptors, respectively.	price>
R-C-2626	SC-9 cas:102649-78-5	SC-9 is a protein kinase C(PKC)activator in the presence of Ca2+.	price>
R-R-4326	Pericyazine CAS No.2622-26-6	Pericyazine (Propericiazine)/CAS No.2622-26-6 is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects.	price>
R-C-2627	PD 180970 CAS:287204-45-9	PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8nM and 50nM, respectively.	price>
R-R-4327	Eticlopride hydrochloride CAS No.97612-24-3	Eticlopride hydrochloride/CAS No.97612-24-3, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent.	price>
R-C-2628	Narciclasine CAS:29477-83-6	Narciclasine is a plant growth modulator.Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway,greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.	price>
R-R-4328	Azaperone CAS No.1649-18-9	Azaperone (R-1929)/CAS No.1649-18-9 acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.	price>
R-C-2629	Chelerythrine CAS: 34316-15-9	Chelerythrine is a natural alkaloid,acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist,with an IC50 of 0.7μM.Chelerythrine has antitumor,antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5μM and displaces Bax from BclXL.Chelerythrine triggers apoptosis and autophagy.	price>
R-R-4329	(±)-Levomepromazine-d6 CAS No.1189805-51-3	(±)-Levomepromazine-d6/CAS No.1189805-51-3 is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.	price>
R-C-2630	Saracatinib (AZD0530) CAS:379231-04-6	Saracatinib(AZD0530)is a potent Src family inhibitor with IC50s of 2.7 to 11nM for c-Src,Lck,c-YES,Lyn,Fyn,Fgr,and Blk.Saracatinib shows high selectivity over other tyrosine kinases.	price>

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