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Catalog	name	Description	price
R-R-4310	Droperidol CAS No.548-73-2	Droperidol/CAS No.548-73-2 is a butyrophenone-type Dopamine-2 receptor antagonist.	price>
R-C-2611	SC-10 CAS:102649-79-6	SC-10 is a PKC activator.It acts by stimulating PKC mediated myosin light chain phosphorylation without activating MLC kinase.	price>
R-R-4311	Loxapine succinate CAS No.27833-64-3	Loxapine succinate/CAS No.27833-64-3 is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages.	price>
R-C-2612	ML347 CAS:1062368-49-3	ML347(DN193719)is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32nM; shows>300-fold selectivity for ALK2 vs.	price>
R-R-4312	Nomifensine CAS No.24526-64-5	Nomifensine/CAS No.24526-64-5 is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters.	price>
R-C-2613	SR-3677 CAS:1072959-67-1	SR-3677 is a novel,potent and highly selective inhibitor of Rho Kinase(ROCK-II) with the IC50 value of ~0.3nM in enzyme and cell based assays.	price>
R-R-4313	A68930 hydrochloride CAS No.130465-39-3	A68930 hydrochloride/CAS No.130465-39-3, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.	price>
R-C-2614	DMH-1 CAS:1206711-16-1	DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5/47.6 nM for ALK1/ALK2/ALK3/ALK6,respectively.	price>
R-R-4314	Amisulpride CAS No.71675-85-9	Amisulpride/CAS No.71675-85-9 is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.	price>
R-C-2615	Midostaurin (PKC412) CAS:120685-11-2	Midostaurin(PKC412;CGP 41251)is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ,Syk,Flk-1,Akt,PKA,c-Kit,c-Fgr,c-Src,FLT3,PDFRβ and VEGFR1/2 with IC50s ranging from 22-500nM.	price>
R-R-4315	Clebopride malate CAS No.57645-91-7	Clebopride malate/CAS No.57645-91-7 is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.	price>
R-C-2616	Calphostin C CAS:121263-19-2	The calphostins are a class of closely related chemical compounds isolated from the fungus Cladosporium cladosporioides.The known calphostins include calphostin A,calphostin B,calphostin C,calphostin D,and calphostin I.The calphostins are inhibitors of protein kinase C(PKC).	price>
R-R-4316	Nomifensine maleate CAS No.32795-47-4	Nomifensine maleate/CAS No.32795-47-4 is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.	price>
R-C-2617	PKC fragment (530-558)	Potent activator of protein kinase C(Ka~10 mM);corresponds to residues 530-558 of the catalytic domain of PKC.	price>
R-R-4317	Pridopidine CAS No.346688-38-8	Pridopidine/CAS No.346688-38-8, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100× higher than its affinity toward D2R.	price>
R-C-2618	Ro 31-8220 Mesylate CAS:138489-18-6	Ro 31-8220 is a PKC-inhibitor,which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate (PMA,IC50=1.35 x 10(-6)M)or diacylglycerols(OAG,diC8)by 95%.Ro-31-8220 showed the apoptotic effect on HL-60 cells,which was mediated by a well-characterized transduction process of apoptotic signals:i.e.,mitochondrial cytochrome c efflux and the activation of caspase-3 in the cytosol.	price>
R-R-4318	Dexpramipexole dihydrochloride CAS No.104632-27-1	Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride)/CAS No.104632-27-1 is a neuroprotective agent and weak non-ergoline dopamine agonist.	price>
R-C-2619	chroman 1 CAS:1273579-40-0	Chroman 1 is a highly potent and selective ROCK II inhibitor.	price>
R-R-4319	LY3154207 CAS No.1638667-79-4	LY3154207/CAS No.1638667-79-4 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM).	price>
R-C-2620	Vactosertib (TEW-7197) CAS:1352608-82-2	Vactosertib(EW-7197)is a potent,orally active and ATP-competitive activin receptor-like kinase 5(ALK5)inhibitor with an IC50 of 12.9nM.Vactosertib also inhibits ALK2 and ALK4(IC50 of 17.3nM)at nanomolar concentrations.Vactosertib has potently antimetastatic activity and anticancer effect.	price>

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