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Catalog	name	Description	price
R-R-4277	MSX-130 CAS No.4051-59-6	MSX-130/CAS No.4051-59-6 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis.	price>
R-C-2578	Necrosulfonamide CAS:1360614-48-7	Necrosulfonamide is a novel inhibitor of MLKL(mixed lineage kinase domain-like). Necrosulfonamide is a cell-permeable inhibitor that covalently modifies Cys88 and blocks human MLKL adaptor function.	price>
R-R-4278	Vimnerixin CAS No.1418112-77-2	Vimnerixin (AZD4721)/CAS No.1418112-77-2 is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease.	price>
R-C-2579	YH239-EE CAS:1364488-67-4	YH239-EE,ethyl ester of the free carboxylic acid compound YH239,is a potent p53-MDM2 antagonizing and apoptosis-inducing agent.	price>
R-R-4279	AZD8309 CAS No.333742-48-6	AZD8309 is an orally active antagonist of CXCR2. AZD8309 has the ability to regulate the transmigration of neutrophils. AZD8309 can be used in the study of inflammatory diseases.	price>
R-C-2580	BM-1074 CAS:1391108-10-3	BM-1074 is a potent Bcl-2/Bcl-xL inhibitor which is capable of achieving rapid, complete,and durable tumor regression in vivo.	price>
R-R-4280	ACT-660602 CAS No.1646267-59-5	ACT-660602/CAS No.1646267-59-5 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. ACT-660602 inhibits T-cell migration and shows efficacy in acute lung ingury model. ACT-660602 can be used for autoimmune diseases research.	price>
R-C-2581	U 73343 CAS:142878-12-4	U-73343,works as a protonophore,is an inactive analog of U-73122 and can be used as a negative control.U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant.U-73122 is a phospholipase C(PLC)and 5-LO(5-lipoxygenase)inhibitor with an IC50 of 1-2.1µM for PLC.	price>
R-R-4281	SCH 563705 CAS No.473728-58-4	SCH 563705/CAS No.473728-58-4 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively.	price>
R-C-2582	WEHI-539 CAS:1431866-33-9	WEHI-539 was designed as a BCL-XLinhibitor with high affinity.It interacted the with the binding groove of BCL-XLwith a Kd value of 0.6nM.In MEF cells lacking MCL-1,WEHI-539 induced apoptosis which was evidenced by the release of mitochondrial cytochrome cand caspase-3 processing.	price>
R-R-4282	CTCE-0214 CAS No.577782-52-6	CTCE-0214/CAS No.577782-52-6 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research.	price>
R-C-2583	SMIP004 CAS:143360-00-3	SMIP004 is a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells.SMIP004 decreased the levels of positive cell cycle regulators, upregulated cyclin-dependent kinase inhibitors,and resulted in G1 arrest, inhibition of colony formation in soft agar,and cell death.	price>
R-R-4283	SRT3109 CAS No.1204707-71-0	SRT3109/CAS No.1204707-71-0 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.	price>
R-C-2584	WR 1065 CAS:14653-77-1	WR 1065,a dephosphorylated metabolite of amifostine(Ethyol),can protect against the immediate and delayed effects of radiation exposure.	price>
R-R-4284	Plerixafor-d4 CAS No.1246819-87-3	Plerixafor-d4/CAS No.1246819-87-3 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM.	price>
R-C-2585	Melphalan CAS:148-82-3	Melphalan is a cytotoxic drug used to treat multiple myeloma.Phenylamine derivative of mechorethamine.	price>
R-R-4285	SB-332235 CAS No.276702-15-9	SB-332235/CAS No.276702-15-9 is a potent, orally active nonpeptide CXCR2 antagonist, with an IC50 of 7.7 nM. SB-332235 displays 285-fold selectivity for CXCR2 over CXCR1. SB-332235 inhibits acute and chronic models of arthritis in the rabbit. SB-332235 inhibits viability of AML cells.	price>
R-C-2586	Nolatrexed (AG-337) CAS:152946-68-4	Nolatrexed dihydrochloride(AG 337)is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme,with a Ki of 11nM for human thymidylate synthase.Nolatrexed dihydrochloride(AG 337)induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity.	price>
R-R-4286	CXCR2 antagonist 2 CAS No.2647464-91-1	CXCR2 antagonist 2/CAS No.2647464-91-1 is a potent CXCR2 antagonist for cancer immunoresearch with an IC50 value of 95 nM.	price>
R-C-2587	A-1210477 CAS:1668553-26-1	A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45nM. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner.	price>

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