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Catalog	name	Description	price
R-C-2534	AMG073 CAS：226256-56-0	Cinacalcet(AMG073,Sensipar,Cin)is an orally active,allosteric agonist of receptors for calcium(CaR)that increases the sensitivity of the CaR to Ca.	price>
R-R-4234	CCK antagonist 1 CAS No.742116-45-6	CCK antagonist 1 (compound 3d)/CAS No.742116-45-6 is a CCK antagonist with IC50s of 1.1 μM and 4 μM for CCK1 and CCK2, respectively. CCK antagonist 1 can be used for research of cancer and mental disease.	price>
R-C-2535	Ambrisentan（BSF208075，LU208075） CAS No. 177036-94-1	Ambrisentan(LU-208075,BSF-208075)is a highly selective antagonist of the endothelin-1 type A receptor,used in the treatment of pulmonary arterial hypertension(PAH).	price>
R-R-4235	AMG 487 CAS No.473719-41-4	AMG 487/CAS No.473719-41-4 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.	price>
R-C-2536	Canagliflozin hemihydrate CAS：928672-86-0	Canagliflozin hemihydrate(JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2nM,3.7nM,and 4.4nM for mSGLT2, rSGLT2,and hSGLT2 in CHOK cells,respectively.	price>
R-R-4236	Reparixin CAS No.266359-83-5	Reparixin/CAS No.266359-83-5 is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively.	price>
R-C-2537	Ipragliflozin (ASP1941) CAS：761423-87-4	Ipragliflozin(ASP1941)is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876nM,6.73 and 1166nM,5.64 and 1380nM for human SGLT2 and SGLT1,rat SGLT2 and SGLT1,mouse SGLT2 and SGLT1,respectively.Antidiabetic agent.	price>
R-R-4237	Plerixafor octahydrochloride CAS No.155148-31-5	Plerixafor octahydrochloride (AMD3100 octahydrochloride)/CAS No.155148-31-5 is a selective CXCR4 antagonist with an IC50 of 44 nM.	price>
R-C-2538	Tofogliflozin(CSG 452) CAS：1201913-82-7	Tofogliflozin(CSG-452)is a potent and highly specific sodium/glucose cotransporter 2(SGLT2)inhibitor with Ki values of 2.9,14.9,and 6.4nM for human, rat,and mouse SGLT2.	price>
R-R-4238	Navarixin CAS No.473727-83-2	Navarixin (SCH 527123)/CAS No.473727-83-2 is a CXCR1 and CXCR2 antagonist that is potent, allosteric, and orally active, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectively.	price>
R-C-2539	Plerixafor（ AMD310） CAS：110078-46-1	Plerixafor(AMD 3100)is a selective CXCR4 antagonist with an IC50 of 44nM.Plerixafor,an immunostimulant and a hematopoietic stem cell(HSC)mobilizer, is an allosteric agonist of CXCR7.Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10nM.	price>
R-R-4239	AZD-5069 CAS No.878385-84-3	AZD-5069/CAS No.878385-84-3 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.	price>
R-C-2540	Ki16198 CAS：355025-13-7	Ki16198 is a potent and orally active LPA receptor antagonist,the methyl ester of Ki16425(HY-13285).Ki16198 inhibits LPA1 and LPA3-induced inositol phosphate production with Ki values of 0.34μM and 0.93μM,respectively.Ki16198 is effective for pancreatic cancer tumorigenesis and metastasis in vivo.	price>
R-R-4240	Mavorixafor trihydrochloride CAS No.2309699-17-8	Mavorixafor trihydrochloride (AMD-070 trihydrochloride)/CAS No.2309699-17-8 is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.	price>
R-C-2541	Oxiracetam CAS：62613-82-5	Oxiracetam is a cyclic derivative of γ-aminobutyric acid(GABA)which has been commonly used as nootropic drug to treat cognitive impairments.	price>
R-R-4241	SCH 546738 CAS No.906805-42-3	SCH 546738/CAS No.906805-42-3 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments.	price>
R-C-2542	Prasugrel CAS：150322-43-3	Prasugrel(PCR 4099),a thienopyridine and prodrug,inhibits platelet function.Prasugrel is an orally active and potent P2Y12 receptor antagonist,and inhibits ADP-induced platelet aggregation.	price>
R-R-4242	SX-682 CAS No.1648843-04-2	SX-682/CAS No.1648843-04-2 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.	price>
R-C-2543	Agomelatine (S-20098) CAS:138112-76-2	Agomelatine(S-20098)is a specific agonist of MT1 and MT2 receptors with Kis of 0.1,0.06,0.12, and 0.27nM for CHO-hMT1,HEK-hMT1,CHO-hMT2,and HEK-hMT2,respectively.Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native(porcine)and cloned, human 5-HT2C receptors, respectively.	price>
R-R-4243	ACT-1004-1239 CAS No.2178049-58-4	ACT-1004-1239/CAS No.2178049-58-4 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM.	price>

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