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Catalog	name	Description	price
R-R-4172	Cenicriviroc Mesylate CAS No.497223-28-6	Cenicriviroc Mesylate (TAK-652 Mesylate)/CAS No.497223-28-6 is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity.	price>
R-C-2473	Darifenacin HBr CAS:133099-07-7	Darifenacin,also known as UK-88525,is a medication used to treat urinary incontinence.Darifenacin works by blocking the M3 muscarinic acetylcholine receptor,which is primarily responsible for bladder muscle contractions.It thereby decreases the urgency to urinate.	price>
R-R-4173	BMS-813160 CAS No.1286279-29-5	BMS-813160/CAS No.1286279-29-5 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC50s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation.	price>
R-C-2474	Flavoxate HCl CAS:3717-88-2	Flavoxate Hydrochloride(DW-61 Hydrochloride)is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.	price>
R-R-4174	J-113863 CAS No.353791-85-2	J-113863/CAS No.353791-85-2 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect.	price>
R-C-2475	Revefenacin CAS:864750-70-9	Revefenacin(TD-4208;GSK1160724)is a potent mAChR antagonist;has a high affinity on M3 receptor with a Ki of 0.18nM.	price>
R-R-4175	Vercirnon CAS No.698394-73-9	Vercirnon (GSK1605786A)/CAS No.698394-73-9 is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively.	price>
R-C-2476	Diphemanil Methylsulfate CAS:62-97-5	Diphemanil Methylsulfate is a quaternary ammonium anticholinergic,it binds muscarinic acetycholine receptors(mAchR).	price>
R-R-4176	CCR7 Ligand 1 CAS No.681514-83-0	CCR7 Ligand 1 (CCR7-Cmp2105)/CAS No.681514-83-0 is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.	price>
R-C-2477	Glycopyrrolate CAS:596-51-0	Glycopyrrolate(Glycopyrronium,Robinul,Gastrodyn)is a muscarinic antagonist used as an antispasmodic,in some disorders of the gastrointestinal tract,and to reduce salivation with some anesthetics.	price>
R-R-4177	BI-6901 CAS No.2040401-92-9	BI 6901/CAS No.2040401-92-9 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research.	price>
R-C-2478	Tropisetron CAS: 89565-68-4	Tropisetron(SDZ-ICS-930 free base)is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1±0.9nM for 5-HT3 receptor.	price>
R-R-4178	INCB 3284 CAS No.887401-92-5	INCB 3284/CAS No.887401-92-5 is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3.7 nM. INCB 3284 can be used in the research of acute liver failure.	price>
R-C-2479	Thonzylamine CAS:91-85-0	Thonzylamine is an orally active H1 histamine receptor antagonist,exhibits good antihistaminic and antianaphylactic properties.Thonzylamine can be used for the research of hypersensitivity diseases,nasal congestion,allergic conjunctivitis and other allergic diseases.	price>
R-R-4179	MK-0812 Succinate CAS No.851916-42-2	MK-0812 Succinate/CAS No.851916-42-2 is a potent and selective CCR2 antagonist with high affinity at CCR2.	price>
R-C-2480	Caulophylline (N-Methylcytisine) CAS:486-86-2	Caulophylline(N-Methylcytisine,Caulophyllin,NMC)is a tricyclic quinolizidine alkaloid with anti-inflammatory activities.Caulophylline binds to nicotinic acetylcholine receptors(nAChR)from squid optical ganglia with Kd of 50nM. Caulophylline significantly reduces myeloperoxidase(MPO)activity,blocks the activation of NF-κB by inhibiting IκB and IKK phosphorylation.	price>
R-R-4180	SB-328437 CAS No.247580-43-4	SB-328437/CAS No.247580-43-4 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM.	price>
R-C-2481	Merafloxacin CAS:91188-00-0	Merafloxacin(CI 934)is a fluoroquinolone antibacterial,which was also identified as a−1 PRF inhibitor of SARS-CoV-2.Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on −1 PRF of other beta coronaviruses.	price>
R-R-4181	ML604086 CAS No.850330-18-6	ML604086/CAS No.850330-18-6 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.	price>
R-C-2482	Hypocrellin A CAS:77029-83-5	Hypocrellin A(HA)is a perylenequinone isolated from Shiraia bambusicola that shows antiviral,antimicrobial and anticancer activity through mediating multiple signaling pathways.Hypocrellin A also is a selective and potent inhibitor of PKC.	price>

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