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Catalog	name	Description	price
R-R-4082	Taranabant CAS No.701977-09-5	Taranabant/CAS No.701977-09-5 is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro.	price>
R-R-4083	Pregnenolone monosulfate sodium CAS No.1852-38-6	Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium)/CAS No.1852-38-6 is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.	price>
R-R-4084	Olorinab CAS No.1268881-20-4	Olorinab (APD 371)/CAS No.1268881-20-4 is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist, with an EC50 of 6.2 nM for hCB2.	price>
R-C-2385	Ruxolitinib (INCB018424) CAS：941678-49-5	Ruxolitinib(INCB018424)is the first potent,selective,JAK1/2 inhibitor to enter the clinic with IC50 of 3.3nM/2.8nM in cell-free assays,>130-fold selectivity for JAK1/2 versus JAK3.Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.	price>
R-R-4085	Yangonin CAS No.500-62-9	Yangonin/CAS No.500-62-9 exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively.	price>
R-C-2386	Cucurbitacin I CAS：2222-07-3	Cucurbitacin-I(Elatericin B,JSI 124,NSC 521777),a natural cell-permeable triterpenoid isolated from Cucurbitaceae,is a novel selective inhibitor of JAK2/STAT3.	price>
R-R-4086	AM281 CAS No.202463-68-1	AM281/CAS No.202463-68-1 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM.	price>
R-C-2387	Propafenone CAS：54063-53-5	Propafenone(SA-79)is an orally active sodium channel blocking agent and a beta-adrenoceptor(β-adrenergic receptor)antagonist.Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.	price>
R-R-4087	LY2828360 CAS No.1231220-79-3	LY2828360/CAS No.1231220-79-3 is a slowly acting but efficacious G protein-biased cannabinoid (CB2) agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling.	price>
R-C-2388	Bisoprolol fumarate CAS:104344-23-2	Bisoprolol is a drug belonging to the group of beta blockers,a class of drugs used primarily in cardiovascular diseases.More specifically,it is a selective type β1 adrenergic receptor blocker.	price>
R-R-4088	Monlunabant CAS No.2712480-46-9	Monlunabant ((S)-MRI-1891)/CAS No.2712480-46-9 is a solid dispersions compound, as well as a cannabinoid CB1 receptor inhibitor.	price>
R-C-2389	Nebivolol CAS: 118457-14-0	Nebivolol is a beta-blocker.It works by affecting the response to nerve impulses in certain parts of the body,like the heart.As a result,the heart beats slower and decreases the blood pressure.When the blood pressure is lowered,the amount of blood and oxygen is increased to the heart.	price>
R-R-4089	(±)-Ibipinabant CAS No.362519-49-1	(±)-Ibipinabant ((±)-SLV319)/CAS No.362519-49-1 is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.	price>
R-C-2390	Carvedilol Phosphate CAS:610309-89-2	Carvedilol Phosphate is the phosphate salt form of carvedilol,a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.	price>
R-R-4090	CB1 antagonist 4 CAS No.1253641-65-4	CB1 antagonist 4 (compound 8)/CAS No.1253641-65-4 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. CB1 antagonist 4 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. CB1 antagonist 4 reduces propensity for psychiatric side effects.	price>
R-C-2391	Methyldopa CAS: 555-30-6	Methyldopa is a centrally acting antihypertensive agent.It is metabolized to alpha-methylnorepinephrine in the brain,and this compound activates central alpha-2 adrenergic receptors.Being a selective agonist for α2 adrenergic receptors,psychoactive drug is used as a sympatholytic or antihypertensive.	price>
R-R-4091	Org 27569 CAS No.868273-06-7	Org 27569/CAS No.868273-06-7 is a potent CB1 receptor allosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling.	price>
R-C-2392	Dronedarone CAS:141626-36-0	Dronedarone(SR33589)is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent.It shows rate-dependent inhibition of the rapid Na+ current,inhibits α and β-adrenergic receptors like Class II agents,exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents(Class IV).	price>
R-R-4092	GW-405833 CAS No.180002-83-9	GW-405833 (L768242)/CAS No.180002-83-9 is a potent, selective cannabinoid receptor 2 (CB2) agonist with an EC50 of 50.7 nM. GW-405833 also behaves as a noncompetitive CB1 antagonist. GW-405833 suppresses inflammatory and neuropathic pain.	price>
R-C-2393	Pimozide CAS:2062-78-4	Pimozide(Orap,R6238)is an antagonist of Dopamine Receptors with Ki of 0.83nM,3.0 nM and 6600nM for dopamine D3,D2 and D1 receptors, respectively.Pimozide also exhibits binding affinity at α2-adrenoceptor and 5-HT1A with Ki of 360nM and 310nM,respectively.Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.	price>

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