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Catalog	name	Description	price
R-R-4142	N-Arachidonyldopamine CAS No.199875-69-9	N-Arachidonyldopamine/CAS No.199875-69-9 is a potent and selective endogenous CB1 receptor agonist with a Ki of 250 nM. N-Arachidonyldopamine is also a potent and selective TRPV1 agonist an with EC50 of ~ 50 nM.	price>
R-C-2443	Loganin CAS:18524-94-2	Loganin(Loganoside)is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica,a member of the Loganiaceae family.It is a non-competitive inhibitor of BACE1 with IC50 of 47.97μM an also inhibits AChE and BChE with IC50 values of 3.95μM and 33.02μM, respectively.	price>
R-R-4143	CB2R/FAAH modulator-2 CAS No.2876918-68-0	CB2R/FAAH modulator-2 (compound 26)/CAS No.2876918-68-0 is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.	price>
R-C-2444	Palmatine CAS:3486-67-7	Palmatine(Berbericinine,Burasaine),an isoquinoline alkaloid,has sedative,antidepressant,antioxidative,anti-ulcerative,antacid,anticancer,and anti-metastatic activities.	price>
R-R-4144	CB1R antagonist 1 CAS No.334668-69-8	CB1R Allosteric modulator 5/CAS No.334668-69-8, a selective cannabinoid-1 receptor (CB1R) inverse agonist with an IC50 value of 4.2 μM and EC50 value of ＞10 μM. CB1R Allosteric modulator 5 can be used for the research of metabolic and obesity.	price>
R-C-2445	Jatrorrhizine chloride CAS:6681-15-8	Jatrorrhizine Chloride is a AChE inhibitor found in Corydalis and Coptydis.It increases expression of p21 and p27 and induces cell cycle arrest in melanoma cells,suppresses amyloid-β-induced toxicity in neurons,inhibits growth of Plasmodium,Leishmania,and Trypanosoma,and increases gastric emptying rates.	price>
R-R-4145	BMS-646256 CAS No.464213-10-3	BMS-646256/Ibipinabant/SLV319/CAS No.464213-10-3 is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM. Ibipinabant shows more than 1000-fold selectivity for CB1 over CB2 (Ki=7943 nM). Ibipinabant can be used for the research of obesity and diabetic.	price>
R-C-2446	Vorinostat (SAHA) CAS:149647-78-9	Vorinostat(suberanilohydroxamic acid)MK-0683 and SAHA,is a potent and selective inhibitor of histone deace tylases (HDACs).Vorinostat has been shown to bind to the active site of histone deacetylases and act as a chelator for Zinc ions also found in the active site of histone deacetylases.	price>
R-R-4146	NIDA-41020 CAS No.502486-89-7	NIDA-41020/CAS No.502486-89-7 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET).	price>
R-C-2447	Tenuifolin CAS:20183-47-5	Tenuifolin,a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.	price>
R-R-4147	MJ15 CAS No.944154-76-1	MJ15/CAS No.944154-76-1 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice.	price>
R-C-2448	Acotiamide CAS:185106-16-5	Acotiamide(Acofide,Z388)is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties.	price>
R-R-4148	GAT228 CAS No.1446648-15-2	GAT228/CAS No.1446648-15-2, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand.	price>
R-C-2449	AR-42 CAS：935881-37-1	AR-42((S)-HDAC-42):AR-42;NSC-736012;OSU-42;OSU-HDAC-42;OSUHDAC-42.AR-42 may possess additional histone-independent mechanisms,which may contribute to its superior profile in vitro and in vivo.	price>
R-R-4149	Pregnenolone (Standard) CAS No.145-13-1	Pregnenolone (Standard)/CAS No.145-13-1 is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.	price>
R-C-2450	M344 CAS：251456-60-7	M344(D 237)is an inhibitor of histone deacetylase(IC50=100nM)and an inducer of terminal cell fifferentiation.	price>
R-R-4150	N-Arachidonyldopamine-d8 CAS No.1159908-42-5	N-Arachidonyldopamine-d8/CAS No.1159908-42-5 is the deuterium labeled N-Arachidonyldopamine.	price>
R-C-2451	Ivermectin (MK-933) CAS： 70288-86-7	Ivermectin(MK-933)is a broad-spectrum anti-parasite agent.Ivermectin(MK-933)is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus.It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor(nAChRs).Ivermectin also inhibits bovine herpesvirus1(BoHV-1)replication and inhibits BoHV-1 DNA polymerase nuclear import.Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19.	price>
R-R-4151	RS 504393 CAS No.300816-15-3	RS 504393/CAS No.300816-15-3 is a selective CCR2 chemokine receptor antagonist (IC50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively).	price>
R-C-2452	PNU-120596 CAS：501925-31-1	PNU-120596(NSC 216666)is a potent and selective α7 nAChR positive allosteric modulator(PMA)with an EC50 of 216 nM.PNU-120596 is inactive against α4β2, α3β4,and α9α10 nAChRs.PNU-120596 has the potential for psychiatric and neurological disorders research.	price>

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