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Catalog	name	Description	price
R-R-3994	Irbesartan CAS No.138402-11-6	Irbesartan (SR-47436)/CAS No.138402-11-6 is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.	price>
R-C-2295	NSC697923 CAS:343351-67-7	NSC697923 is a potent UBE2N(ubiquitin-conjugating enzyme E2 N,Ubc13) inhibitor. NSC697923 induces neuroblastoma(NB)cell death via promoting nuclear importation of p53 in p53 wild-type NB cells.NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway.NSC697923 inhibits DNA damage and NF-κB signaling.Antitumor activity.	price>
R-R-3995	Olmesartan CAS No.144689-24-7	Olmesartan (RNH-6270)/CAS No.144689-24-7 is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure.	price>
R-C-2296	Levetiracetam (UCB-L059) CAS:102767-28-2	Levetiracetam, an antiepileptic agent,binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis.Levetiracetam modulates HDAC levels ultimately silencing MGMT,thus increasing Temozolomide effectiveness.A chemosensitizer agent.	price>
R-R-3996	Olodanrigan CAS No.1316755-16-4	Olodanrigan (EMA401)/CAS No.1316755-16-4 is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.	price>
R-C-2297	Cilnidipine (FRC-8653) CAS:132203-70-4	Cilnidipine(FRC-8653)is a calcium channel blocker.Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function.It was approved in 1995.Compared with other calcium antagonists,cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists.	price>
R-R-3997	PD 123319 ditrifluoroacetate CAS No.136676-91-0	PD 123319 (ditrifluoroacetate)/CAS No.136676-91-0 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.	price>
R-C-2298	MCU-i4 CAS:371924-24-2	MCU-i4 is a negative modulator of the mitochondrial calcium uniporter (MCU)complex that directly binds a specific cleft in MICU1 and decreases mitochondrial Ca2+ influx.	price>
R-R-3998	Azilsartan medoxomil CAS No.863031-21-4	Azilsartan medoxomil (TAK 491)/CAS No.863031-21-4 is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.	price>
R-C-2299	Amlodipine maleate CAS:88150-47-4	Amlodipine maleate is a dihydropyridine calcium channel blocker,acts as an orally active antianginal agent.Amlodipine maleate blocks the voltage-dependent L-type calcium channels,thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer.	price>
R-R-3999	Angiotensin II 5-valine CAS No.58-49-1	Angiotensin II 5-valine/CAS No.58-49-1 is an agonist of angiotensin receptor.	price>
R-C-2300	Loureirin B CAS:119425-90-0	Loureirin B(LB,LrB),a flavonoid extracted from Dracaena cochinchinensis,is an inhibitor of PAI-1 with IC50 of 26.10μM.Loureirin B downregulates p-ERK and p-JNK in TGF-β1-stimulated fibroblasts.Loureirin B promotes insulin secretion mainly through increasing Pdx-1,MafA,intracellular ATP level,inhibiting the KATP current,influx of Ca2+ to the intracellular.	price>
R-R-4000	Olmesartan medoxomil CAS No.144689-63-4	Olmesartan medoxomil/CAS No.144689-63-4 is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.	price>
R-C-2301	Ranolazine CAS:95635-55-5	Ranolazine(CVT 303)is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current(INa and IKr with IC50 values of 6μM and 12μM, respectively)without affecting heart rate or blood pressure(BP).Ranolazine is also a partial fatty acid oxidation(FAO)inhibitor.Antianginal agent.	price>
R-R-4001	Benzyl benzoate CAS No.120-51-4	Benzyl benzoate (Phenylmethyl benzoate)/CAS No.120-51-4 is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry.	price>
R-C-2302	Isradipine CAS: 75695-93-1	Isradipine(PN 200-110)is an orally active L-type calcium channel blocker.Isradipine,as a powerful peripheral vasodilator,is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation.Isradipine is a potentially viable neuroprotective agent for Parkinson is disease.	price>
R-R-4002	2-(1,1-Dioxidobenzo[b]thien-3(2H)-ylidene)propanedinitrile CAS:74228-25-4	2-(1,1-Dioxidobenzo[b]thien-3(2H)-ylidene)propanedinitrile/CAS:74228-25-4 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time.	price>
R-C-2303	Felodipine CAS:72509-76-3	Felodipine,a dihydropyridine,is a potent,vasoselective calcium channel antagonist.Felodipine lowers blood pressure(BP)by selective action on vascular smooth muscle,especially in the resistance vessels.Felodipine,an anti-hypertensive agent,induces autophagy.Felodipine can cross the blood-brain barrier.	price>
R-R-4003	2-(6-Oxo-5,6-dihydro-4H-cyclopenta[C]thiophen-4-ylidene)malononitrile CAS :2099010-83-8	2-(6-Oxo-5,6-dihydro-4H-cyclopenta[C]thiophen-4-ylidene)malononitrile/CAS :2099010-83-8 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time.	price>
R-C-2304	Manidipine CAS:89226-50-6	Manidipine is a calcium channel blocker(dihydropyridine type)that is used clinically as an antihypertensive.Manidipine is a lipophilic,third-generation dihydropyridine calcium channel antagonist with a high degree of selectivity for the vasculature,thereby inducing marked peripheral vasodilation with negligible cardiodepression.In addition,manidipine does not significantly affect norepinephrine levels,suggesting a lack of sympathetic activation.	price>

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