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Catalog | name | Description | price |
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R-R-3889 | PP/Fe3O4 composite aerogel | PP/Fe3O4 composite aerogel;Polypropylene/Fe3O4 composite aerogel from ruixi.The polypropylene/Fe3O4 composite aerogel is an advanced material resulting from the combination of nanoporous, lightweight polypropylene with iron(II,III) oxide (Fe3O4) nanoparticles. The polypropylene/Fe3O4 composite aerogel offers a unique combination of magnetic properties, mechanical strength, catalytic activity, biomedical imaging potential, adsorption capabilities, thermal conductivity, lightweight structure, and reusability. These properties make it applicable in industries such as biotechnology, environmental science, catalysis, nanotechnology, materials engineering, and healthcare. | price> |
R-C-2190 | Nilotinib (AMN-107) CAS: 641571-10-0 | Nilotinib(AMN107)is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.Nilotinib is a selective Bcr-Abl kinase inhibitor that is 10-30 fold more potent than imatinib in inhibiting Bcr-Abl tyrosine kinase activity and proliferation of Bcr-Abl expressing cells. | price> |
R-R-3890 | PP/BaTiO3 composite aerogel | PP/BaTiO3 composite aerogel;Polypropylene/barium titanate composite aerogel;PP/barium titanate composite aerogel;Polypropylene/BaTiO3 composite aerogel from ruixi. The polypropylene/barium titanate composite aerogel is an innovative material resulting from the combination of nanoporous, lightweight polypropylene with barium titanate nanoparticles. The polypropylene/barium titanate composite aerogel presents exceptional dielectric properties, tunable electrical behavior, mechanical flexibility, energy storage potential, sensing capabilities, lightweight structure, and potential thermal stability. These properties make it applicable in industries such as electronics, telecommunications, energy storage, sensors, and advanced materials for various technological applications. | price> |
R-C-2191 | Danusertib (PHA-739358) CAS:827318-97-8 | Danusertib(PHA-739358)is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases,which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed.This agent may preferentially bind to and inhibit Aurora B kinase.Aurora kinases,a family of serine-threonine kinases,are important regulators of cellular proliferation and division. | price> |
R-R-3891 | PP/TiO2 composite aerogel | PP/TiO2 composite aerogel;Polypropylene/titanium dioxide composite aerogel;PP/titanium dioxide composite aerogel;Polypropylene/TiO2 composite aerogel from ruixi.The polypropylene/titanium dioxide composite aerogel is a cutting-edge material formed by combining nanoporous, lightweight polypropylene with titanium dioxide nanoparticles. The polypropylene/titanium dioxide composite aerogel offers outstanding photocatalytic activity, UV protection, lightweight structure, mechanical flexibility, antimicrobial properties, potential use in photovoltaic applications, and environmental remediation capabilities. These properties make it applicable in industries such as environmental engineering, materials science, construction, healthcare, and renewable energy, among others. | price> |
R-C-2192 | Degrasyn (WP1130) CAS:856243-80-6 | WP1130(Degrasyn)is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia(CML)cells. | price> |
R-R-3892 | Levobetaxolol hydrochloride CAS No.116209-55-3 | Levobetaxolol hydrochloride/CAS No.116209-55-3 is a beta-adrenergic receptor inhibitor (beta blocker) that can lower the pressure in the eye. | price> |
R-C-2193 | KW-2449 CAS:1000669-72-6 | KW-2449 is a multi-targeted kinase inhibitor of FLT3,ABL,ABLT315I and Aurora kinase with IC50s of 6.6,14,4 and 48nM.respectively. | price> |
R-R-3893 | Tizanidine CAS No.51322-75-9 | Tizanidine/CAS No.51322-75-9 is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. | price> |
R-C-2194 | PP121 CAS:1092788-83-4 | PP121 is a dual inhibitor of receptor tyrosine kinases(RTKs)(IC50<0.02μM for Abl,Src,VEGFR-2 and PDGFR)and PI 3-K family kinases(IC50<0.06μM for p110α,DNA-PK and mTOR). | price> |
R-R-3894 | Harmane-d | Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). | price> |
R-C-2195 | Nocodazole (R17934) CAS: 31430-18-9 | Nocodazole(Oncodazole)is a rapidly-reversible inhibitor of microtubule.Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics,which prevents mitosis and induces apoptosis in tumor cells.Nocodazole inhibits Bcr-Abl,and activates CRISPR/Cas9. | price> |
R-R-3895 | Tizanidine-d4 CAS No.1188331-19-2 | Tizanidine-d4/CAS No.1188331-19-2 is the deuterium labeled Tizanidine. Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. | price> |
R-C-2196 | Rebastinib (DCC-2036) CAS:1020172-07-9 | Rebastinib(DCC-2036,)is an orally bioavailable small-molecule inhibitor of multiple tyrosine kinases with potential antineoplastic activity.Multitargeted tyrosine kinase inhibitor DCC-2036 binds to and inhibits the Bcr-Abl fusion oncoprotein by changing the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation;in addition,this agent binds to and inhibits Src family kinases LYN,HCK and FGR and the receptor tyrosine kinases TIE-2 and VEGFR-2. | price> |
R-R-3896 | Metoprolol-d7 hydrochloride CAS No.1219798-61-4 | Metoprolol-d7 (hydrochloride)/CAS No.1219798-61-4 is the deuterium labeled Metoprolol. Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties. | price> |
R-C-2197 | Dasatinib hydrochloride CAS:854001-07-3 | Dasatinib(BMS-354825)hydrochloride is a highly potent,ATP competitive,orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity.The Kis are 16 pM and 30 pM for Src and Bcr-Abl,respectively.Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0nM and 0.5nM, respectively.Dasatinib hydrochloride also induces apoptosis and autophagy. | price> |
R-C-2287 | BC-1215 CAS:1507370-20-8 | BC-1215 is an inhibitor of F-box protein 3(FBXO3,a ubiquitin E3 ligase component,IC50=0.9μg/mL for IL-1β release).BC-1215 decreases Fbxo3-Fbxl2 interaction and prevents SCFFbxo3 catalyzed Fbxl2 ubiquitination.BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1–TRAF6. BC-1215,interacts with ApaG to profoundly inhibit secretion of a broad spectrum of TH1 panel cytokines from human PBMC. | price> |
R-R-3897 | Prazosin-d8 CAS No.1006717-55-0 | Prazosin-d8/CAS No.1006717-55-0 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. | price> |
R-C-2198 | PD173955 CAS:260415-63-2 | PD-173955 is a src tyrosine kinase inhibitor.PD173955 inhibited Bcr-Abl-dependent cell growth.PD173955 has an IC(50)of 1-2 nM in kinase inhibition assays of Bcr-Abl,and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation.PD173955 inhibited kit ligand-dependent c-kit autophosphorylation(IC(50)=approximately 25nM)and kit ligand-dependent proliferation of M07e cells(IC(50)=40nM)but had a lesser effect on interleukin 3-dependent(IC(50)=250nM)or granulocyte macrophage colony-stimulating factor (IC(50)=1 microM)-dependent cell growth. | price> |
R-C-2288 | THAL-SNS-032 CAS:2139287-33-3 | THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon(CRBN). | price> |