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Catalog	name	Description	price
R-R-3862	Desglymidodrine CAS No.3600-87-1	Desglymidodrine (ST 1059)/CAS No.3600-87-1, the active metabolite of Midodrine (HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure.	price>
R-C-2163	Linderalactone CAS:728-61-0	Linderalactone inhibits human lung cancer growth by modulating the expression of apoptosis-related proteins(Bax and Bcl-2)with an IC50 of 15µM in A-549 cells. Linderalactone induces G2/M cell cycle arrest and could also suppress the JAK/STAT signalling pathway.	price>
R-R-3863	Metipranolol hydrochloride CAS No.36592-77-5	Metipranolol hydrochloride/CAS No.36592-77-5 is a non-selective β adrenergic receptor blocking agent.	price>
R-C-2164	PF-06826647 CAS:2127109-84-4	PF-06826647 is an orally active and selective TYK2 inhibitor(IC50=17nM),which binds to TYK2 catalytically active JH1 domain.PF-06826647 displays selectivity for TYK2 over JAK1(IC50=383nM)and JAK2(74nM).PF-06826647 can be used for the research of psoriasis,ulcerative colitis, and hidradenitis suppurativa.	price>
R-R-3864	Dicentrine CAS No.517-66-8	Dicentrine/CAS No.517-66-8 is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates.	price>
R-C-2165	TG101209 CAS:936091-14-4	TG101209 is a selective JAK2 inhibitor with IC50 of 6nM, less potent to Flt3 and RET(c-RET)with IC50 of 25 nM and 17nM in cell-free assays,~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.	price>
R-R-3865	HOKU-81 CAS No.58020-43-2	HOKU-81 (4-Hydroxytulobuterol)/CAS No.58020-43-2 is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect.	price>
R-C-2166	Upadacitinib (ABT-494) CAS:1310726-60-3	Upadacitinib（ABT-494)is a potent and selective JAK inhibitors in development for rheumatoid arthritis.ABT-494 is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific,relevant cytokines.ABT-494 demonstrates efficacy in rat arthritis models.	price>
R-R-3866	(S)-Carvedilol CAS No.95094-00-1	(S)-Carvedilol/CAS No.95094-00-1, the S-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (S)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).	price>
R-C-2167	Abrocitinib (PF-04965842) CAS:1622902-68-4	Abrocitinib(PF-04965842)is a potent,orally active and selective JAK1 inhibitor, with IC50s of 29 and 803nM for JAK1 and JAK2,respectively.Abrocitinib(PF-04965842)exhibits less active effect on TYK2(IC50,1.253μM),and inhibits phosphorylation of STAT1,STAT3 and STAT5 after stimulation.Effective in autoimmune disease.	price>
R-R-3867	FFN270 hydrochloride CAS No.2341841-05-0	FFN270 hydrochloride/CAS No.2341841-05-0, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors.	price>
R-C-2168	Itacitinib (INCB39110) CAS:1334298-90-6	INCB39110 is a potent JAK1 tyrosine kinase inhibitor,which is currently in Phase II trials for the treatment of rheumatoid arthritis,myelofibrosis,rheumatoid arthritis and plaque psoriasis.	price>
R-R-3868	PSF/SiO2 composite aerogel	PSF/SiO2 composite aerogel;Polysulfone/silica composite aerogel;PSF/silica composite aerogel;Polysulfone/SiO2 composite aerogel from ruixi.The combination of polysulfone and silica in the composite aerogel results in a lightweight material with exceptional thermal insulation, robust mechanical strength, and resistance to harsh chemicals and high temperatures. The high surface area of silica also contributes to its excellent absorption and adsorption capabilities.This composite aerogel is well-suited for a variety of applications, including thermal insulation in aerospace and industrial settings, as a lightweight structural material, for filtration purposes, and as a component in high-temperature and chemical-resistant composites. Its properties make it valuable for applications where a lightweight, thermally insulating material with excellent mechanical strength and chemical resistance is essential.	price>
R-C-2169	Panobinostat (LBH589) CAS:404950-80-7	Panobinostat(LBH589,NVP-LBH589)is a novel broad-spectrum HDAC inhibitor with IC50 of 5nM in a cell-free assay.Panobinostat(LBH589) induces autophagy and apoptosis.Panobinostat effectively disrupts HIV latency in vivo.	price>
R-R-3869	PSF/ZnO composite aerogel	PSF/ZnO composite aerogel;Polysulfone/zinc oxide composite aerogel;PSF/zinc oxide composite aerogel;Polysulfone/ZnO composite aerogel from ruixi. A composite aerogel consisting of polysulfone and zinc oxide brings together the distinctive properties of both materials, resulting in a versatile substance with a variety of valuable characteristics.The combination of polysulfone and zinc oxide results in a lightweight material with superior mechanical strength, chemical resistance, antimicrobial properties, and UV-blocking capabilities. The composite aerogel is well-suited for various applications such as antimicrobial coatings, UV protection coatings, and in environmental remediation where photocatalytic properties are beneficial. Additionally, it may find use in electronic and optoelectronic devices thanks to its electrical and optical properties.	price>
R-C-2170	ACY-775 CAS:1375466-18-4	ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6)with an IC50 of 7.5nM.	price>
R-R-3870	PSF/ZrO2 composite aerogel	PSF/ZrO2 composite aerogel;Polysulfone/zirconia composite aerogel;PSF/zirconia composite aerogel;Polysulfone/ZrO2 composite aerogel from ruixi.A composite aerogel made from polysulfone and zirconia combines the unique properties of both materials, resulting in a material with a diverse range of valuable characteristics.This composite aerogel is well-suited for applications requiring lightweight, high-strength materials with excellent thermal and chemical resistance. It could find use in aerospace components, high-temperature insulation, and as a structural material in environments where resistance to harsh conditions is essential. Additionally, its enhanced mechanical properties make it valuable for applications that require durable and resilient materials.	price>
R-C-2171	MC1568 CAS:852475-26-4	MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase,resulting in the death of breast cancer cells by apoptosis.	price>
R-R-3871	PSF/Al2O3 composite aerogel	PSF/Al2O3 composite aerogel;Polysulfone/alumina composite aerogel;PSF/alumina composite aerogel;Polysulfone/Al2O3 composite aerogel from ruixi.A composite aerogel made from polysulfone and alumina combines the distinctive properties of both materials, resulting in a versatile material with a variety of valuable characteristics.This composite aerogel is exceptionally lightweight, offering enhanced mechanical strength, thermal stability, and chemical resistance. It is well-suited for applications such as high-temperature insulation, aerospace components, and structural materials in harsh environments requiring resistance to extreme temperatures and corrosive substances. Additionally, its high strength and rigidity make it suitable for applications that demand durable and resilient materials.	price>
R-C-2172	Givinostat (ITF2357) CAS: 732302-99-7	Givinostat(ITF2357)is a potent HDAC inhibitor for maize HD2,HD1B and HD1A with IC50 of 10 nM,7.5nM and 16nM in cell-free assays.	price>

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