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Catalog	name	Description	price
R-C-2102	Ingliforib CAS：186392-65-4	Ingliforib is a glycogen phosphorylase inhibitor,with IC50s of 52,352 and 150nM for liver,muscle and brain glycogen phosphorylase,and has cardioprotective activity.	price>
R-R-3802	Tizanidine hydrochloride CAS No.64461-82-1	Tizanidine hydrochloride/CAS No.64461-82-1 is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.	price>
R-C-2103	Batefenterol CAS：743461-65-6	Batefenterol(GSK961081;TD-5959)is a novel muscarinic receptor antagonist and β2-adrenoceptor agonist;displays high affinity for hM2,hM3 muscarinic and hβ2-adrenoceptor with Ki values of 1.4,1.3 and 3.7nM,respectively.	price>
R-R-3803	Lofexidine hydrochloride CAS No.21498-08-8	Lofexidine (hydrochloride)/CAS No.21498-08-8 is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.	price>
R-C-2104	BAR 502 CAS：1612191-86-2	BAR502 is a dual FXR and GPBAR1 agonist.BAR-502 promotes browning of white adipose tissue and reverses liver steatosis and fibrosis.BAR502 protects against liver damage caused by HFD by promoting the browning of adipose tissue.	price>
R-R-3804	Ritodrine hydrochloride CAS No.23239-51-2	Ritodrine (DU21220) hydrochloride/CAS No.23239-51-2 is a β-adrenergic agonist, also an effective smooth muscle and uterine relaxant. Ritodrine hydrochloride prolongs contraction interval, can be used for researching arrest premature labor.	price>
R-C-2105	BAR 501 CAS： 1632118-69-4	BAR501 is a potent and selective G protein-coupled bile acid receptor 1(GPBAR1, GPCR19,TGR5)agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1μM.	price>
R-R-3805	Indoramin CAS No.26844-12-2	Indoramin/CAS No.26844-12-2 is an orally active antihypertensive agent. Indoramin is also selective for the α1A-adrenoceptor.	price>
R-C-2106	GSK3117391 CAS：1018673-42-1	GSK3117391(GSK3117391A)and HDAC-IN-3,is a potent HDAC inhibitor for treating chronic inflammatory disorders.	price>
R-R-3806	Bucindolol CAS No.71119-11-4	Bucindolol/CAS No.71119-11-4 is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure.	price>
R-C-2107	PZ-2891 CAS：2170608-82-7	PZ-2891 is an orally bioavailable,brain penetrant pantothenate kinase (PANK)modulator.PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations.PZ-2891 inhibits human pantothenate kinases PANK1β,PANK2,and PANK3 with IC50s of 40.2 nM,0.7nM and 1.3nM,respectively.	price>
R-R-3807	(R)-Terazosin CAS No.109351-34-0	(R)-Terazosin/CAS No.109351-34-0 is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent α1-adrenoceptor antagonist with Ki values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively.	price>
R-C-2108	LJ570 CAS：2252488-69-8	LJ570 is the first PPARα/γDual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes.LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones,without showing their typical side effects.LJ570 may be useful for treatment of dyslipidemic type 2 diabetes.	price>
R-R-3808	Phentolamine CAS No.50-60-2	Phentolamine/CAS No.50-60-2 is a potent, selective and orally active α1 adrenergic and α2 adrenergic receptor antagonist. Phentolamine can be used for the research of erectile dysfunction.	price>
R-C-2109	AWZ1066S CAS：2239272-16-1	AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis,with an EC50 of 2.5nM in cell assay.	price>
R-R-3809	(RS)-Butyryltimolol CAS No.2320274-78-8	(RS)-Butyryltimolol/CAS No.2320274-78-8 is the racemate of Butyryltimolol. Butyryltimolol, an effective proagent of Timolol, improves the corneal penetration of Timolol. Butyryltimolol is a β-adrenergic blocker.	price>
R-C-2110	LUT-014 CAS：2274819-46-2	LUT014 is a B-Raf inhibitor with an IC50 of 11.7nM,and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment.Extracted from patent WO 2019026065A2.	price>
R-R-3810	Solabegron CAS No.252920-94-8	Solabegron (GW 427353)/CAS No.252920-94-8 is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.	price>
R-C-2111	Spastazoline CAS：2351882-11-4	Spastazoline is a potent,cell-permeable and selective spastin(a microtubule-severing AAA(ATPases associated with diverse cellular activities) protein)inhibitor with IC50 of 99nM for Human spastin.Spastazoline does not inhibit ATPase activity of a recombinant human VPS4(another AAA protein required for intercellular bridge disassembly).	price>
R-R-3811	Scopine CAS No.498-45-3	Scopine/CAS No.498-45-3 is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.	price>

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