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Catalog	name	Description	price
R-C-2106	GSK3117391 CAS：1018673-42-1	GSK3117391(GSK3117391A)and HDAC-IN-3,is a potent HDAC inhibitor for treating chronic inflammatory disorders.	price>
R-R-3806	Bucindolol CAS No.71119-11-4	Bucindolol/CAS No.71119-11-4 is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure.	price>
R-C-2107	PZ-2891 CAS：2170608-82-7	PZ-2891 is an orally bioavailable,brain penetrant pantothenate kinase (PANK)modulator.PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations.PZ-2891 inhibits human pantothenate kinases PANK1β,PANK2,and PANK3 with IC50s of 40.2 nM,0.7nM and 1.3nM,respectively.	price>
R-R-3807	(R)-Terazosin CAS No.109351-34-0	(R)-Terazosin/CAS No.109351-34-0 is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent α1-adrenoceptor antagonist with Ki values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively.	price>
R-C-2108	LJ570 CAS：2252488-69-8	LJ570 is the first PPARα/γDual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes.LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones,without showing their typical side effects.LJ570 may be useful for treatment of dyslipidemic type 2 diabetes.	price>
R-R-3808	Phentolamine CAS No.50-60-2	Phentolamine/CAS No.50-60-2 is a potent, selective and orally active α1 adrenergic and α2 adrenergic receptor antagonist. Phentolamine can be used for the research of erectile dysfunction.	price>
R-C-2109	AWZ1066S CAS：2239272-16-1	AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis,with an EC50 of 2.5nM in cell assay.	price>
R-R-3809	(RS)-Butyryltimolol CAS No.2320274-78-8	(RS)-Butyryltimolol/CAS No.2320274-78-8 is the racemate of Butyryltimolol. Butyryltimolol, an effective proagent of Timolol, improves the corneal penetration of Timolol. Butyryltimolol is a β-adrenergic blocker.	price>
R-C-2110	LUT-014 CAS：2274819-46-2	LUT014 is a B-Raf inhibitor with an IC50 of 11.7nM,and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment.Extracted from patent WO 2019026065A2.	price>
R-R-3810	Solabegron CAS No.252920-94-8	Solabegron (GW 427353)/CAS No.252920-94-8 is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.	price>
R-C-2111	Spastazoline CAS：2351882-11-4	Spastazoline is a potent,cell-permeable and selective spastin(a microtubule-severing AAA(ATPases associated with diverse cellular activities) protein)inhibitor with IC50 of 99nM for Human spastin.Spastazoline does not inhibit ATPase activity of a recombinant human VPS4(another AAA protein required for intercellular bridge disassembly).	price>
R-R-3811	Scopine CAS No.498-45-3	Scopine/CAS No.498-45-3 is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.	price>
R-C-2112	KL1333 CAS：1800405-30-4	KL1333,a derivative of β-lapachone,is an orally available NAD+modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1(NQO1)as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts.KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures.	price>
R-R-3812	Carbazochrome sodium sulfonate CAS No.51460-26-5	Carbazochrome sodium sulfonate (AC-17)/CAS No.51460-26-5 is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent.	price>
R-C-2113	VUN34002（Vanin-1-IN-1 ） CAS：2173134-00-2	Vanin-1-IN-1 is an inhibitor of vanin-1 enzyme which is a cell surface associated,giycosyiphosphatidyS inositol(GPi)anchored protein and plays an important role in metabolism and inflammation.	price>
R-R-3813	(+)-Penbutolol CAS No.38363-41-6	(+)-Penbutolol/CAS No.38363-41-6 is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.	price>
R-C-2114	Danicopan CAS： 1903768-17-1	Danicopan(ACH-4471,ACH-0144471,ACH-CFDIS,ALXN 2040)is a potent,selective and orally active inhibitor of factor D with Kd of 0.54nM for human Factor D. Danicopan inhibits alternative pathway of complement(APC)activity,and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria(PNH)and atypical hemolytic uremic syndrome(aHUS).	price>
R-R-3814	Todralazine hydrochloride CAS No.3778-76-5	Todralazine hydrochloride (Ecarazine hydrochloride)/CAS No.3778-76-5 is an anti-hypertensive agent, acts as a β2AR blocker, with antioxidant and free radical scavenging activity.	price>
R-C-2115	LML-134 CAS：1542135-76-1	LML134(compound 18b)is an orally active and high selective Histamine 3 receptor (H3R)inverse agonist with Kis of 0.3nM and 12nM for hH3R cAMP and hH3R bdg. LML134 penetrates the brain rapidly,leading to high H3R occupancy,and disengages its target with a fast kinetic profile.LML134 has the potential for excessive sleep disorders.	price>
R-R-3815	Bufuralol hydrochloride CAS No.60398-91-6	Bufuralol (Ro 3-4787) hydrochloride/CAS No.60398-91-6 is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a CYP2D6 probe substrate.	price>

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