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R-R-3632 PCL silk fibroin electrospun membrane PCL silk fibroin electrospun membrane/Polycaprolactone silk fibroin electrospun membrane from ruixi. PCL silk fibroin electrospun membranes are composite materials created through the electrospinning process, combining Polycaprolactone (PCL) and silk fibroin. PCL silk fibroin electrospun membranes represent an exciting and promising material for tissue engineering, regenerative medicine, and related biomedical fields, given their ability to provide a biomimetic microenvironment that supports cell growth and tissue regeneration. This particular combination of materials opens up new avenues for advancing biomedical research and clinical applications. price>
R-C-1933 ALVELESTAT (AZD 9668) CAS:848141-11-7 Alvelestat(AZD9668,Avelestat)is an oral,highly selective inhibitor of neutrophil elastase(NE)with IC50 and Ki of 12nM and 9.4nM,at least 600-fold more selective over other serine proteases.  price>
R-R-3633 PLA/gelatin electrospun nanofiber membrane Polylactic acid/gelatin electrospun nanofiber membrane is a nanofiber membrane material that combines polylactic acid (PLA) and gelatin. Polylactic acid is a biodegradable polymer material with good mechanical properties and biocompatibility; gelatin is a natural polymer material derived from animal bones and skin and other tissues, and has good biological activity and adhesion. Through electrospinning technology, polylactic acid and gelatin can be combined to form a nanoscale fiber membrane. This membrane material combines the advantages of both and shows better performance and application prospects.Polylactic acid (gelatin) electrospun nanofiber membrane has high specific surface area, high porosity and good biological activity, so it can provide a good environment for cell growth and material transmission, promote cell adhesion and proliferation, in addition, due to the adhesiveness of gelatin This kind of fiber membrane also has good adhesion properties and can closely adhere to the tissue surface, helping to repair and regenerate the tissue. In the field of tissue engineering, polylactic acid/gelatin electrospinning nanofiber membrane can be used as a scaffold material, supports the growth and differentiation of cells, and promotes tissue regeneration and repair. At the same time, due to the biodegradability of polylactic acid, this fiber membrane material can be gradually degraded and absorbed in the body, avoiding the need for secondary surgical removal. In addition , polylactic acid/gelatin electrospun nanofiber membranes can also be used in fields such as drug delivery, wound dressings and biosensors. By loading bioactive substances such as drugs or growth factors, sustained release and targeted delivery of drugs can be achieved, improving drug delivery. therapeutic effect and reduce side effects. price>
R-C-1934 BAY 80-6946 CAS:1032568-63-0 Copanlisib(BAY80-6946)is a potent,selective and ATP-competitive pan-class I PI3K inhibitor,with IC50s of 0.5nM,0.7nM,3.7nM and 6.4nM for PI3Kα,PI3Kδ,PI3Kβ and PI3Kγ,respectively.Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases,except for mTOR. Copanlisib has superior antitumor activity. price>
R-R-3634 PLGA composite silk fibroin electrospun fiber membrane PLGA composite silk fibroin electrospun fiber membrane/Poly(lactic-co-glycolic acid) composite silk fibroin electrospun fiber membrane from ruixi. PLGA composite silk fibroin electrospun fiber membrane is an electrospun fiber membrane material that combines Poly(lactic-co-glycolic acid) (PLGA) and silk fibroin. PLGA is a biodegradable polyester with good mechanical properties and biocompatibility, while silk fibroin is a natural polymer protein with good biological activity and mechanical properties. Through electrospinning technology, PLGA and silk fibroin can be combined to form nanoscale fiber membranes with high specific surface area and porosity, providing a good environment for cell growth and material transmission. PLGA composite silk fibroin electrospun fiber membrane has broad application prospects in the biomedical field, such as tissue engineering, drug delivery, wound dressings, etc. Its good biocompatibility and mechanical properties can promote cell adhesion and proliferation, thereby promoting tissue regeneration and repair. At the same time, the biodegradability of PLGA allows this fiber membrane material to be gradually degraded and absorbed in the body, avoiding the need for secondary surgical removal. In addition, the PLGA composite silk fibroin electrospun fiber membrane can also be adjusted by adjusting spinning parameters and adding Growth factors and other methods are modified to improve its performance and functionality. For example, bioactive substances such as growth factors can be added to promote cell differentiation and functional expression. price>
R-C-1935 RRx-001 CAS:925206-65-1 RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity.It inhibits glucose 6-phosphate dehydrogenase(G6PD)in human tumor cells,binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity. price>
R-R-3635 Glutaraldehyde cross-linked PVA membrane Glutaraldehyde cross-linked polyvinyl alcohol membrane/Glutaraldehyde cross-linked PVA membrane from ruixi.Glutaraldehyde cross-linked polyvinyl alcohol (PVA) membranes are a type of specialized material that has found extensive use in biomedical and separation applications. Glutaraldehyde cross-linked polyvinyl alcohol (PVA) membranes represent an innovative advancement in membrane technology, particularly in biomedical and separation applications. The controlled cross-linking process introduces valuable properties that enable the membranes to be used effectively in tissue engineering, controlled drug delivery, and precise separation processes. These membranes continue to play a significant role in various fields due to their tailored characteristics and specific applications. price>
R-C-1936 GIGANTOL CAS:67884-30-4 Gigantol is a bibenzyl compound derived from several medicinal orchids.Giganto shows promising therapeutic potential against cancer cells.Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. price>
R-R-3636 PLGA silk fibroin nanofiber membrane PLGA silk fibroin nanofiber membrane/Poly(lactic-co-glycolic acid) silk fibroin nanofiber membrane from ruixi. PLGA (Poly(lactic-co-glycolic acid)) silk fibroin nanofiber membranes are a combination of biocompatible and biodegradable polymers that have been engineered at the nanoscale level. PLGA silk fibroin nanofiber membranes offer a unique combination of properties, including biocompatibility, biodegradability, high surface area, and mechanical flexibility, making them valuable in various biomedical applications. These membranes continue to be a subject of intense interest for researchers and engineers working in tissue engineering, drug delivery, wound healing, and regenerative medicine due to their tailored properties and versatile applications. price>
R-C-1937 S119-8 CAS:443639-96-1 S119-8 is a broad spectrum inhibitor of influenza A and B viruses,showing activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus,but does not inhibit a non-influenza virus,vesicular stomatitis nirus(VSV). price>
R-R-3637 PAN electrospun fiber membrane PAN electrospun fiber membrane/Polyacrylonitrile electrospun fiber membrane from ruixi. The PAN nanofiber membrane prepared by electrospinning has better piezoelectric properties than PVDF nanofiber membrane. The static charge in PAN nanofibers facilitates the conversion of piezoelectric energy. The electrical energy generated by PAN nanofiber films can provide power for commercial LEDs. Nanomaterials prepared by electrospinning can be applied in various fields such as biopolymer materials, battery separators, filtration materials, catalysts, sensors, etc price>
R-C-1938 NAV-2729 CAS: 419547-11-8 NAV-2729 is a selective ARF6 inhibitor(IC50=1.0μM).Blocking ARF6 with a small-molecule inhibitor reduces uveal melanoma cell proliferation and tumorigenesis in a mouse model,confirming the functional relevance of this pathway and suggesting a therapeutic strategy for Gα-mediated diseases. price>
R-R-3638 PCL-SF electrospun fiber membrane PCL-SF electrospun fiber membrane/Polycaprolactone-SilkFibroin electrospun fiber membrane from ruixi.Electrospun fiber membranes made from a blend of polycaprolactone (PCL) and silk fibroin (SF) are advanced materials that find diverse applications in biomedical engineering, tissue regeneration, and drug delivery systems. Electrospun fiber membranes made from a blend of PCL and SF offer a unique combination of biocompatibility, mechanical strength, and controlled drug delivery capabilities. These membranes are valuable in a range of biomedical applications, including tissue engineering, wound healing, and controlled drug release systems, owing to their tailored characteristics and versatile potential in various therapeutic and regenerative medicine applications. price>
R-C-1939 INF-39 CAS:866028-26-4 INF39 is a nontoxic,irreversible NLRP3 inhibitor that counteracts NLRP3 activation through direct irreversible interaction with NLRP3 and partial inhibition of LPS-driven pro-inflammatory gene expression. price>
R-R-3639 Ppy ps membrane Ppy ps membrane/Polypyrrole polystyrene membrane from ruixi.A polypyrrole (Ppy) polystyrene (PS) membrane is a composite material that combines the unique properties of polypyrrole and polystyrene, offering a range of applications in fields such as electrochemistry, sensors, and filtration.Ppy-PS membranes represent a versatile composite material with a unique combination of electrical conductivity, selective permeability, and chemical stability. Their potential applications span various fields, including electrochemistry, sensors, filtration, energy storage, and biomedical engineering, making them an area of interest for researchers and engineers seeking advanced materials with tailored properties for specific applications. price>
R-C-1940 FTBMT CAS:1358575-02-6 FTBMT is a selective GPR52 agonist.It demonstrates antipsychotic-like and procognitive effects in rodents and has revealed a potential therapeutic agent for schizophrenia. price>
R-R-3640 PLGA-PCL electrospun fiber membrane PLGA-PCL electrospun fiber membrane/poly(lactic-co-glycolic acid)-polycaprolactone electrospun fiber membrane from ruixi. The blend of poly(lactic-co-glycolic acid) (PLGA) and polycaprolactone (PCL) in an electrospun fiber membrane introduces a combination of properties that make it a valuable material for various biomedical applications. The PLGA-PCL electrospun fiber membrane is a versatile composite material with a unique combination of biocompatibility, mechanical strength, and controlled drug delivery capabilities. Its potential applications span tissue engineering, drug delivery systems, wound healing, and regenerative medicine, making it an area of interest for researchers and practitioners in the biomedical and pharmaceutical fields. price>
R-C-1941 VU0155069 (CAY10593) CAS:1130067-06-9 VU0155069(CAY10593),compound 69,is a selective phospholipase D1(PLD1)inhibitor with an IC50 value of 46 nM in vitro.VU0155069(CAY10593)strongly inhibits the invasive migration of several cancer cell lines in transwell assays. price>
R-R-3641 PLGA doped sulfated chitosan spinning membrane PLGA doped sulfated chitosan spinning membrane/Polycaprolactone doped sulfated chitosan spinning membrane/PLGA doped SCS spinning membrane from ruixi.PLGA doped sulfated chitosan spinning membrane is a spinning membrane material that combines polylactic acid polycaprolactone (PLGA) and sulfated chitosan (SCS) and has a specific size (12 cm x 13 cm) . This membrane material is prepared through spinning technology and combines the advantages of PLGA and SCS, showing unique performance and application prospects.As a biodegradable polyester, PLGA has good mechanical properties and biocompatibility, while sulfated chitosan (SCS) is a sulfated chitosan biodegradable product with good biological activity. and ion exchange capacity. Combining PLGA and SCS to form a spinning membrane can combine the advantages of both and improve the biological activity, mechanical properties and ion exchange capacity of the material. This spinning membrane material has high specific surface area, high porosity and good water absorption, so it can provide a good environment for cell growth and material transmission. At the same time, the ion exchange capacity of sulfated chitosan gives it excellent adsorption properties and biological activity, which can promote cell adhesion and proliferation and further promote tissue regeneration and repair. PLGA rubber phenolized chitosan spinning membrane has wide application prospects in the fields of tissue engineering, drug delivery, wound dressings and biosensors. For example, it can be used as a scaffold material to support the growth and differentiation of cells and promote tissue regeneration and repair; it can also be used as a carrier for drugs to achieve sustained release and targeted delivery of drugs, improve the therapeutic effect of drugs and reduce side effects. price>
R-C-1942 IK1 inhibitor PA-6 CAS:500715-03-7 IK1 inhibitor PA-6(PA-6),a pentamidine analogue,is a selective and potent IK1(KIR2.x ion-channel-carried inward rectifier current)inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents.IK1 inhibitor PA-6(PA-6)elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation.IK1 inhibitor PA-6(PA-6)has the potential to treat atrial fibrillation and arrhythmia. price>