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Catalog	name	Description	price
R-R-3622	Levonordefrin CAS No.829-74-3	Levonordefrin/CAS No.829-74-3, a common alternative to levoepinephrine as a vasoconstrictor in dental local anesthetic preparations, is usually used in fivefold higher concentrations. Levonordefrin is generally considered equivalent to epinephrine.	price>
R-C-1923	MK-8617 CAS：1187990-87-9	MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3(HIF PHD1-3)with an IC50 of 1nM for PHD2.	price>
R-R-3623	Practolol CAS No.6673-35-4	Practolol/CAS No.6673-35-4 is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias.	price>
R-C-1924	S63845 CAS：1799633-27-4	S63845 is a potent and selective myeloid cell leukemia 1(MCL1)inhibitor with a Kd of 0.19nM for human MCL1.	price>
R-R-3624	Salmeterol xinafoate CAS No.94749-08-3	Salmeterol (GR 33343X) xinafoate/CAS No.94749-08-3 is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.	price>
R-C-1925	PF05175157 CAS：1301214-47-0	PF-05175157 is a potent and selective cetyl-CoA carboxylase(ACC)1 and 2 inhibitor with IC50 values of 27nM and 33 nM,respectively.PF-05175157 led to robust reduction of de novo lipogenesis(DNL),albeit with concomitant reductions in platelet count,which were attributed to the inhibition of fatty acid synthesis within bone marrow.PF-05175157 induced a reduction of the viral load in serum and kidney in WNV-infected mice,unveiling its therapeutic potential for the treatment of chronic kidney disease associated with persistent WNV infection.	price>
R-R-3625	Olodaterol hydrochloride CAS No.869477-96-3	Olodaterol (BI1744) hydrochloride/CAS No.869477-96-3 is a selective, long acting β2-adrenoceptor (β2-AR) agonist (EC50=0.1 nM and pKi= 9.14 for human β2-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis.	price>
R-C-1926	PF06291874 CAS：1393124-08- 7	PF-06291874(Glucagon receptor antagonists-4)is a highly potent and orally active glucagon receptor antagonist.It displays low in vivo clearance in both rats and dogs.	price>
R-R-3626	Bufuralol CAS No.54340-62-4	Bufuralol (Ro 3-4787)/CAS No.54340-62-4 is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a CYP2D6 probe substrate.	price>
R-C-1927	Cilofexor （GS-9674) CAS：1418274-28-8	Cilofexor(GS-9674)is a potent,selective and orally active nonsteroidal FXR agonist with an EC50 of 43nM.Cilofexor has anti-inflammatory and antifibrotic effects.Cilofexor has the potential for primary sclerosing cholangitis(PSC)and nonalcoholic steatohepatitis(NASH)research.	price>
R-R-3627	Betaxolol hydrochloride CAS No.63659-19-8	Betaxolol Hydrochloride/CAS No.63659-19-8 is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.	price>
R-C-1928	Tipifarnib S enantiomer CAS：192185-71-0	Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib.Tipifarnib is a potent and specific farnesyltransferase(FTase)inhibitor with IC50 of 0.6nM.Tipifarnib S enantiomer is the less active isomer.	price>
R-R-3628	PCL electrospun membrane	PCL electrospun membrane/PCL electrospun film/Polycaprolactone electrospun membrane/Polycaprolactone electrospun film from ruixi.PCL electrospinning membrane is a polycaprolactone (PCL) nanofiber membrane prepared by electrospinning technology. PCL is a linear hydrophobic synthetic polymer with high mechanical strength and good biocompatibility, so it is widely used in fields such as drug carriers, degradable plastics, and nanofiber spinning.PCL electrospun membrane has high specific surface area, high pore removal rate and good mechanical properties. These characteristics make it an ideal choice in the fields of tissue engineering, drug delivery and wound materials, as a tissue engineering scaffold material. PCL statically spun membrane can provide a three-dimensional growth space for cells, support cell growth and differentiation, and promote tissue regeneration. As a drug delivery carrier, PCL electrospun membrane can load drugs and control the release rate of drugs, achieve targeted delivery and sustained release of drugs, improve the therapeutic effect of drugs and reduce side effects. In addition, due to its good biocompatibility and mechanical properties, PCL electrospun membrane can also be used in wound dressings to provide protection and support for wounds and promote wound healing.However, the performance and application of PCL electrospinning membranes may be affected by factors such as spinning parameters, fiber morphology and composition. Therefore, in-depth research and optimization are needed to improve the performance and application effects of PCL electrospun membranes.	price>
R-C-1929	AM966 CAS：1228690-19-4	AM966 is a high affinity,selective,oral LPA1-antagonist,inhibits LPA-stimulated intracellular calcium release(IC50=17nM).	price>
R-R-3629	PCL gelatin nanofiber membrane	PCL gelatin nanofiber membrane/Polycaprolactone gelatin nanofiber membrane from ruixi. PCL gelatin nanofiber membranes are composite materials produced through electrospinning, combining Polycaprolactone (PCL) and gelatin.Nanomaterials prepared by electrospinning can be used in various fields such as biopolymer materials, battery separators, filter materials, catalysts, sensors, etc.	price>
R-C-1930	AM095 CAS: 1228690-36-5	AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chinese hamster ovary(CHO)cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73μM,respectively,and exhibited no LPA1 agonism.Lysophosphatidic acid(LPA)is a bioactive phospholipid that signals through a family of at least six G protein-coupled receptors designated LPA1-6. LPA type 1 receptor(LPA1)exhibits widespread tissue distribution and regulates a variety of physiological and pathological cellular functions.	price>
R-R-3630	PCL hyaluronic acid nanofiber membrane	PCL hyaluronic acid nanofiber membrane/Polycaprolactone hyaluronic acid nanofiber membrane from ruixi.PCL hyaluronic acid nanofiber membranes are composite materials produced through the electrospinning process, integrating Polycaprolactone (PCL) and hyaluronic acid. The tailored properties of PCL hyaluronic acid nanofiber membranes make them suitable for a wide range of potential biomedical applications, such as wound dressings, drug delivery systems, and scaffolds for tissue engineering. The ability to modify the physical characteristics of the membrane, including pore size, porosity, and degradation kinetics, through adjusting the electrospinning parameters makes it highly versatile for specific tissue engineering requirements.	price>
R-C-1931	EHT5372 CAS :1425945-63-6	EHT 5372 is a highly potent and selective inhibitor of DYRK isfamily kinases with IC50s of 0.22,0.28,10.8,93.2,22.8,88.8,59.0,7.44,221 nM for DYRK1A,DYRK1B,DYRK2,DYRK3,CLK1,CLK2,CLK4,GSK-3α,GSK-3β.	price>
R-R-3631	PCL silk fibroin nanofiber membrane	PCL silk fibroin nanofiber membrane/Polycaprolactone silk fibroin nanofiber membrane from ruixi.PCL silk fibroin nanofiber membrane is a nanofiber membrane material that combines polycaprolactone (PCL) and silk fibroin. As a biodegradable polyester, PCL has good mechanical properties and biocompatibility, while silk fibroin is a natural polymer protein with good biological activity and mechanical properties. Combining PCL and silk fibroin to form a nanofiber membrane can combine the advantages of both and improve the biocompatibility, mechanical properties and functionality of the material. Pcl silk fibroin nanofiber membranes are also usually prepared by electrospinning. By controlling the spinning parameters, fibers with nanometer diameters can be obtained. This fiber membrane material has high specific surface area, high porosity and good biological activity, so it can be used in tissue engineering, wound dressings, drug delivery and biosensors. In addition, due to the good biocompatibility and biological activity of silk fibroin, the Pcl silk fibroin nanofiber membrane can also promote cell adhesion and proliferation, thereby promoting tissue regeneration and repair. Therefore, this material has broad application prospects in the biomedical field.	price>
R-C-1932	Verubecestat (MK-8931)	Verubecestat(MK-8931)is an orally active,high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2nM and 0.38nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer is Disease.	price>

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