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Catalog	name	Description	price
R-C-1726	Vemurafenib (PLX4032) CAS:918504-65-1	Vemurafenib(PLX4032,RG7204,RO5185426)is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay.10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.Vemurafenib(PLX4032,RG7204)induces autophagy.	price>
R-R-3426	Brexpiprazole-d8 CAS No.1427049-21-5	Brexpiprazole-d8/CAS No.1427049-21-5 is a deuterium labeled Brexpiprazole (OPC-34712). Brexpiprazole, an atypical antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine receptor (Ki=0.12 nM and 0.3 nM, respectively). Brexpiprazole is also a 5-HT2A receptor antagonist (Ki=0.47 nM).	price>
R-C-1727	Boceprevir (SCH-503034) CAS:394730-60-0	Boceprevir(EBP 520)is a potent, highly selective,orally bioavailable HCV NS3 protease inhibitor with a Ki of 14nM in both enzyme assay and an EC90 of 350nM in cell-based replicon assay.Boceprevir inhibits SARS-CoV-2 3CLpro activity.	price>
R-R-3427	Agomelatin-d3 CAS No.1079389-38-0	Agomelatin-d3/CAS No.1079389-38-0 is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively.	price>
R-C-1728	Doxorubicin (Adriamycin) HCl CAS:25316-40-9	Doxorubicin(Adriamycin,NSC 123127,DOX,Hydroxydaunorubicin)HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage,mitophagy and apoptosis in tumor cells.Doxorubicin reduces basal phosphorylation of AMPK.Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.	price>
R-R-3428	Cinitapride CAS No.66564-14-5	Cinitapride/CAS No.66564-14-5 is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research.	price>
R-C-1729	Besifloxacin hydrochloride CAS: 405165-61-9	Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.	price>
R-R-3429	EMDT oxalate CAS No.263744-72-5	EMDT oxalate/CAS No.263744-72-5 is a selective 5-HT6 agonist, and has antidepressant effects.	price>
R-C-1730	FGF-401 CAS: 1708971-55-4	Roblitinib(FGF401)is an FGFR4-selective inhibitor with an IC50 of 1.1nM.It binds in a reversible covalent manner to the FGFR4 kinase domain and shows at least 1,000 fold selectivity against of panel of 65 kinases in biochemical assays.	price>
R-R-3430	Lerisetron CAS No.143257-98-1	Lerisetron/CAS No.143257-98-1 is a potent 5-HT3 antagonists and possess high-affinity binding for the 5-HT3 receptors with pKi value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats.	price>
R-C-1731	Vorapaxar (MK-5348) CAS: 618385-01-6	Vorapaxar(SCH 530348),an antiplatelet agent,is a selective,orally active,and competitive thrombin receptor protease-activated receptor(PAR-1)antagonist (Ki=8.1nM).Vorapaxar(SCH 530348)inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner.	price>
R-R-3431	Brexpiprazole-d8-1 CAS No.1427049-19-1	Brexpiprazole-d8-1/CAS No.1427049-19-1 is the deuterium labeled Brexpiprazole[1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM).	price>
R-C-1732	Lobeline hydrochloride CAS:134-63-4	Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine.It is also a VMAT2 ligand and an antagonist of μ-opioid receptors.	price>
R-R-3432	CP 93129 dihydrochloride CAS No.879089-64-2	CP 93129 dihydrochloride/CAS No.879089-64-2 is a potent 5HT1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson disease research.	price>
R-C-1733	Emixustat Hydrochlorde cas:1141934-97-5	Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232±3nM.	price>
R-M-G27	Boron nitride doped nanowire aerogel	Boron nitride-doped nanowire aerogel material/Boronnitride-doped nanowire aerogel material is a new composite material that combines the advantages of boron nitride and nanowire aerogel. This material not only inherits the high specific surface area, low density and good thermal insulation properties of nanowire aerogels, but also further improves its high temperature resistance, high strength and toughness properties through the doping of boron nitride. As a high-performance ceramic material, boron nitride has the characteristics of high temperature resistance, oxidation resistance and chemical stability. Doping chess pieces into nanowire aerogels can improve the thermal stability and mechanical properties of the material. At the same time, the nanowire aerogel itself has a three-dimensional network structure and a high specific surface area, which is conducive to the uniform dispersion and stable existence of boron nitride nanoparticles.	price>
R-C-1734	Olopatadine Hydrochlorde CAS:140462-76-6	Olopatadine hydrochloride is a dual acting histamine H1-receptor antagonist and mast cell stabilizer.	price>
R-M-G28	N-doped TiO2/C-NFC aerogel	N-doped TiO2/C-NFC aerogel;N-doped Titanium Dioxide/C-NFC aerogel;N-doped TiO2/Carbon Nanofiber aerogel;N-doped Titanium Dioxide/Carbon Nanofiber aerogel from ruixi. The N-doped TiOz/C-NFC aerogel type adsorption-photodegradation integrated material is a combination of N-doped TiOz nanoparticles, carbon nanofiber aerogel (C-NFC) and adsorption photodegradation-integration functions. of composite materials. This material not only inherits the high specific surface area and adsorption performance of carbon nanofiber aerogels, but also imparts photocatalytic degradation capabilities through the introduction of N-doped TiOz, thereby achieving rapid adsorption and photocatalytic degradation of organic pollutants. C-NFC aerogel has a high specific surface area and porous structure, and has strong adsorption capacity for organic pollutants.	price>
R-C-1735	Gamithromycin CAS :145435-72-9	Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006μg/mL,respectively.	price>
R-M-G29	C-NFC/CS aerogel	C-NFC/CS aerogel;Carbon Nanofiber/Chitosan Aerogel;C-NFC/Chitosan Aerogel;Carbon Nanofiber/CS aerogel from ruixi. C-NFC/CS aerogel adsorbent material is a composite adsorbent material that combines the advantages of carbon nanofiber aerogel (C-NFC) and chitosan (CS). This material not only inherits C-NFC has high specific surface area, electrical conductivity and mechanical Performance, and its biocompatibility and adsorption performance are also enhanced by introducing CS, thus showing broad application prospects in the fields of sewage treatment, heavy metal ion removal, and biomedicine.	price>

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