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Catalog	name	Description	price
R-C-1686	MK 0557 CAS:328232-95-7	MK-0557 is a highly selective,orally administered neuropeptide NPY5R antagonist,could limit weight regain after very-low-calorie diet(VLCD)-induced weight loss.Neuropeptide Y(NPY)is a potent orexigenic neuropeptide,and antagonism of NPY Y1 and NPY Y5 receptors(NPYxR)is considered a potentially important anti-obesity drug target.	price>
R-R-3386	Prucalopride-13C,d3 CAS No.2140306-00-7	Prucalopride-13C,d3/CAS No.2140306-00-7 is the 13C- and deuterium labeled Prucalopride.	price>
R-C-1687	NMS-P118 CAS：1262417-51-5	NMS-P118 is a potent,orally available,and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles,showing 150-fold selectivity for PARP-1 over PARP-2(Kd 0.009μM vs 1.3μM,respectively).	price>
R-R-3387	LY 344864 racemate CAS No.186543-64-6	LY 344864 racemate/CAS No.186543-64-6 is a 5-HT1F receptor agonist extracted from patent US 5708187 A.	price>
R-C-1688	Basmisanil CAS：1159600-41-5	Basmisanil(RG1662,RO5186582)is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome.As of August 2015,it is in phase II clinical trials for this indication.Down syndrome(DS)is the most commonly identifiable genetic form of intellectual disability.Individuals with DS have considerable deficits in intellectual functioning(i.e.,low intellectual quotient,delayed learning and/or impaired language development)and adaptive behavior.	price>
R-R-3388	Hydroxy ziprasidone CAS No.884305-08-2	Hydroxy ziprasidone/CAS No.884305-08-2 is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist.	price>
R-C-1689	ONO-4059 analogue CAS：1351635-67-0	ONO-4059 analog is the analog of ONO-4059,ONO-4059 is a highly potent and selective Btk inhibitor.	price>
R-R-3389	Gepirone-d8 CAS No.2749331-28-8	Gepirone-d8/CAS No.2749331-28-8 is deuterium labeled Gepirone.	price>
R-C-1690	CP21R7(CP21) CAS ：125314-13-8	CP21R7 is potent GSK-3β inhibitor,with an IC50 of 1.8 nM;CP21R7 also shows inhibitory activitiy against PKCα,with an IC50 of 1900 nM.	price>
R-R-3390	(Rac)-Rotigotine hydrochloride CAS No.102120-99-0	(Rac)-Rotigotine hydrochloride/CAS No.102120-99-0 is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.	price>
R-C-1691	UNC0379 CAS：1620401-82-2	UNC0379 is a selective,substrate-competitive inhibitor of the lysine methyltransferase SETD8.Its affinity to SETD8 was confirmed by ITC(isothermal titration calorimetry)and SPR(surface plasmon resonance) studies.	price>
R-R-3391	Pardoprunox hydrochloride CAS No.269718-83-4	Pardoprunox (SLV-308) hydrochloride/CAS No.269718-83-4 is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively.	price>
R-C-1692	Acebilustat CAS：943764-99-6	Acebilustat(CTX-4430)is a leukotriene A4 hydrolase inhibitor,used for an oral antiinflammatory drug.	price>
R-R-3392	Isocorynoxeine CAS No.51014-29-0	Isocorynoxeine/CAS No.51014-29-0, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.	price>
R-C-1693	T0901317 CAS：293754-55-9	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5μM,respectively.T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM,respectively.T0901317 significantly suppresses cell proliferation and induces apoptosis.	price>
R-R-3393	Lintopride CAS No.107429-63-0	Lintopride/CAS No.107429-63-0 is a 5HT4 antagonist with moderate 5HT3 antagonist properties.	price>
R-C-1694	GSK-189254 CAS：720690-73-3	GSK189254A(GSK189254)is a novel,potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.	price>
R-R-3394	Lesopitron dihydrochloride CAS No.132449-89-9	Lesopitron dihydrochloride/CAS No.132449-89-9 is a full and selective 5-HT1A receptor agonist with IC50 of 125 nM in rat hippocampal membranes.	price>
R-C-1695	E 7449 CAS：1140964-99-3	E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2,with IC50s of 2.0,1.0,∼50 and∼50 nM for PARP1,PARP2,TNKS1 and TNKS2,respectively,using 32P-NAD+ as substrate.	price>
R-R-3395	Lidanserin CAS No.73725-85-6	Lidanserin (ZK-33839)/CAS No.73725-85-6 acts as a 5-HT2A and α1-adrenergic receptor antagonist.	price>

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