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R-C-1666 NQ301 CAS:130089-98-4 NQ301(Compound 211),an antiplatelet and antithrombotic agent,is a selective CD45 inhibitor with IC50 of 200 nM.NQ301 inhibits thromboxane A2 receptor(TXA2)and synthase activity in rabbit platelets. price>
R-AC-0010 Polyamine (PA) aerogel Polyamine (PA) aerogel/Polyamine aerogel/PA aerogel from ruixi. The high specific surface area and pore structure of polyamide aerogels make it an adsorbent material. It can be used to adsorb heavy metal ions, organic pollutants, etc. from aqueous solutions to achieve purification of wastewater. Polyamide aerogels can also be used for the separation and purification of gases, such as hydrogen, oxygen, etc. The porous structure and good thermal stability of polyamide aerogel make it a catalyst support. By loading the catalyst active components on the aerogel, the dispersion, stability and catalytic activity of the catalyst can be improved. Polyamide aerogels are widely used in petrochemical, environmental protection and other fields. The preparation of polyamide aerogels usually uses the sol-gel method, using polyamide as the precursor, and forming a three-dimensional network structure through reactions such as hydrolysis and polycondensation. During the preparation process, the pore structure, specific surface area and mechanical properties of the airgel can be controlled by adjusting factors such as reaction conditions, additive types and concentrations. price>
R-C-1667 TPEN CAS:16858-02-9 TPEN is a heavy metal chelator.Reacts with both Zn-proteome and Zn-metallothionein(MT)in LLC-PK1 cells;acts as an intracellular chelator of proteomic Zn2+. price>
R-AC-0011 Polyvinylidene chloride (PVDF) aerogel Polyvinylidene chloride (PVDF) aerogel/Polyvinylidene chloride aerogel/PVDF aerogel is a remarkable material known for its lightweight structure, high porosity, and excellent thermal insulation properties. This aerogel is derived from polyvinylidene chloride, a polymer with strong hydrogen bonding and high tensile strength.PVDF aerogels possess a highly porous network structure, characterized by interconnected nanoscale pores, resulting in an extremely low density. This composition enables the aerogel to exhibit exceptional thermal insulation capabilities, making it suitable for a wide range of applications such as thermal insulation in aerospace, construction, and advanced clothing materials.Furthermore, PVDF aerogels also demonstrate promising potential in areas such as oil spill cleanup, as well as in medical and environmental applications due to their high surface area and adsorption capacity. These properties make PVDF aerogels a versatile material with diverse potential uses across various industries. price>
R-C-1668 SB366791 CAS:472981-92-3 SB-366791 is a potent,competitive and selective vanilloid receptor(VR1/TRPV1) antagonist with IC50 of 5.7 1.2nM target:VR1/TRPV1 IC 50:5.7±1.2 nM[1]SB-366791 produced a concentration-dependent inhibition of the response to capsaicin with an apparent pKb of 7.74±0.08. price>
R-AC-0012 Polypyrrole (pPy) aerogel Polypyrrole (pPy) aerogel/Polypyrrole aerogel/pPy aerogel is a highly porous, lightweight material with a three-dimensional network structure composed of interconnected nanoparticles of polypyrrole. This aerogel is derived from polypyrrole, a conductive polymer known for its unique electrical and optical properties.Polypyrrole aerogels find utility in areas such as energy storage devices, including supercapacitors and batteries, due to their high surface area and excellent electrical conductivity. Additionally, they are being investigated for applications in catalysis, sensors, and as supports for various functional materials.The lightweight nature, combined with the conductive properties of polypyrrole aerogels, positions them as promising materials for advanced technological applications across different industries. price>
R-C-1669 AG-1478 (Tyrphostin AG-1478) CAS:153436-53-4 AG-1478(Tyrphostin AG-1478,NSC 693255)is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays,almost no activity on HER2-Neu,PDGFR, Trk,Bcr-Abl and InsR.AG-1478(Tyrphostin AG-1478)inhibits encephalomyocarditis virus(EMCV)and hepatitis c virus(HCV)by targeting phosphatidylinositol 4-kinase IIIα(PI4KA). price>
R-AC-0013 CPI/PI aerogel composite CPI/PI aerogel has a good porous structure, the specific surface area reaches 245 m^(2)/g, and the PI aerogel has excellent mechanical properties (elastic modulus above 10 MPa); the calcined CPI effectively improves the PI The aerogel has photocatalytic efficiency for oxytetracycline solution and has good cycle regeneration stability. The degradation rate of oxytetracycline solution after 5 cycles is 76%. price>
R-C-1670 WHI-P258 CAS:21561-09-1 WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72uM. price>
R-AC-0014 Cellulose based @ ZnFe2O4 composite aerogel A cellulose-based @ ZnFe2O4 composite aerogel is a novel material that combines the benefits of cellulose and zinc ferrite (ZnFe2O4) within a porous, lightweight structure. Cellulose, a biodegradable and renewable natural polymer, forms the scaffold of the composite aerogel. The inclusion of zinc ferrite nanoparticles further enhances its functionality.This composite aerogel exhibits a highly porous and interconnected network structure, providing a large surface area and effective porosity. As a result, it demonstrates commendable properties such as lightweight nature, excellent absorbency, and potential for multifunctional applications.The presence of zinc ferrite within the cellulose matrix allows for additional functionalities, such as magnetic properties and potential applications in fields like wastewater treatment, catalysis, and biomedical engineering. The composite magnetic properties make it suitable for applications requiring magnetic separation or targeted drug delivery, among other uses.The combination of cellulose and ZnFe2O4 in this composite aerogel results in a versatile material with potential applications in diverse fields, including environmental remediation, biotechnology, and advanced materials science. price>
R-C-1671 Salermide CAS:1105698-15-4 Salermide is a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.Salermide was well tolerated by mice at concentrations up to 100 muM and prompted tumour-specific cell death in a wide range of human cancer cell lines.The antitumour activity of Salermide was primarily because of a massive induction of apoptosis. price>
R-AC-0015 Particle type bulk TiO2 aerogel Particle type bulk TiO2 aerogel/Particle type bulk Titania aerogel from ruixi. Using butyl titanate as raw material, acid-catalyzed particle-shaped bulk TiO2 aerogel was successfully prepared using sol-gel method and supercritical drying, and its structural properties were studied using BET, TEM, SEM, IR and other instruments. Characterization. The results show that the aerogel has a high specific surface area (713.9m2/g) and a low density (the lowest is 35mg/cm3). The network distribution is uneven, the pore size is small, and the pore size distribution is mainly concentrated in 10~ 25nm. Infrared spectrum shows that the aerogel is composed of titanium oxyhydroxides and has no carbon-oxygen bonds. price>
R-C-1672 Adelmidrol CAS;1675-66-7 Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ.Adelmidrol reduces NF-κB translocation,and COX-2 expression. price>
R-AC-0016 High performance nanocomposites TiO2@SiO2 Aerogel TiO2@SiO2 aerogels are high-performance nanocomposites that exhibit exceptional properties due to their unique structure. These aerogels are composed of a titanium dioxide (TiO2) framework encapsulated within a silica (SiO2) matrix, creating a hierarchical nanostructure with remarkable characteristics. TiO2@SiO2 aerogels possess an incredibly high surface area, which is advantageous for various applications such as catalysis, adsorption, and energy storage. The high surface area is attributed to the nanoporous nature of aerogels.The aerogel structure consists of interconnected nanopores, forming a highly porous network. This exceptional porosity contributes to its lightweight nature and high adsorption capacity, making it suitable for applications in environmental remediation and filtration. TiO2@SiO2 aerogels have diverse applications including but not limited to environmental remediation, energy storage, thermal insulation, catalysis, sensors, and biomedical engineering due to their exceptional properties. price>
R-C-1673 Idelalisib (CAL-101, GS-1101) CAS:870281-82-6 Idelalisib (CAL-101,GS-1101)is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays;shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ,and 400- to 4000-fold more selectivity to p110δ than C2β,hVPS34,DNA-PK and mTOR.Idelalisib also stimulates autophagy. price>
R-AC-0017 AgBr/titanium silicate aerogel AgBr/titanium silicate aerogels;Silver bromide/titanium silicate aerogel ;AgBr/Ti silicate aerogel;Silver bromide/Ti silicate aerogel are advanced nanocomposites known for their exceptional properties and diverse applications. These aerogels consist of silver bromide (AgBr) nanoparticles incorporated within a titanium silicate matrix, resulting in a unique composite material with a range of advantageous characteristics.The presence of AgBr in the titanium silicate aerogel imparts significant photocatalytic properties. These aerogels are capable of initiating photochemical reactions under light irradiation, making them valuable for applications such as environmental remediation, water purification, and air treatment.AgBr/titanium silicate aerogels represent a promising class of nanocomposite materials with unique properties that make them suitable for a wide range of applications, including environmental remediation, antibacterial surfaces, optical devices, and energy-related technologies. price>
R-C-1674 ETC-1002 CAS:738606-46-7 ETC-1002(Bempedoic acid,ESP-55016),also known as Bempedoic acid, is an orally available,once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase(AMPK).It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29uM). price>
R-AC-0018 Cerium neodymium doped titanium dioxide/carbon hybrid aerogels Cerium and neodymium doped titanium dioxide/carbon hybrid aerogels; Ce and Nd doped TiO2/carbon hybrid aerogels;Cerium and neodymium doped TiO2/carbon hybrid aerogels;Ce and Nd doped titanium dioxide/carbon hybrid aerogels are advanced nanocomposite materials that exhibit exceptional properties and are utilized across various fields due to their unique structure and composition. These aerogels are composed of titanium dioxide (TiO2) doped with cerium (Ce) and neodymium (Nd), integrated with a carbon framework, resulting in a multifunctional material with a wide range of advantageous characteristics. cerium and neodymium doped titanium dioxide/carbon hybrid aerogels represent a highly versatile class of nanocomposite materials, offering a unique combination of properties suitable for applications in environmental remediation, energy storage, flexible electronics, and beyond. price>
R-C-1675 AR7 CAS:80306-38-3 AR7 is an atypical RARA/RARα(retinoic acid receptor,alpha)antagonist.AR7 specifically activates chaperone-mediated-autophagy(CMA)activity without affecting macroautophagy. price>
R-AC-0019 TiO2/RGO aerogel TiO2/RGO aerogel;Titanium dioxide/RGO aerogel from ruixi. The preparation method and application belong to the technical fields of material preparation and environmental purification. Using cysteine as the reducing agent and cross-linking agent, TiO2 is loaded on RGO airgel through a simple one-step hydrothermal method for the first time to form TiO2/RGO airgel. The gel has a macrostructure of 2.0cm in diameter and 3.5cm in height. price>