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Catalog	name	Description	price
R-C-1616	A804598 CAS:1125758-85-1	A-804598 is a CNS penetrant,competitive and selective P2X7 receptor antagonist with IC50s of 9 nM,10nM and 11 nM for mouse,rat and human P2X7 receptors, respectively.	price>
R-R-3316	Iferanserin CAS No.58754-46-4	Iferanserin (S-MPEC)/CAS No.58754-46-4 is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment.	price>
R-C-1617	GW4869 CAS:6823-69-4	GW4869(GW69A,GW554869A)is a neutral,noncompetitive inhibitor of sphingomyelinase (SMase)with an IC50 of 1μM.It is selective for N-SMase,and does not inhibit acid SMase at up to at least 15μM.	price>
R-R-3317	Olanzapine-d3 CAS No.786686-79-1	Olanzapine-d3/CAS No.786686-79-1 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic.	price>
R-C-1618	BAW2881 CAS： 861875-60-7	NVP-BAW2881(BAW2881)is a potent and selective VEGFR2 inhibitor with an IC50 of 4nM.	price>
R-R-3318	Keto Ziprasidone CAS No.884305-07-1	Keto Ziprasidone/CAS No.884305-07-1 is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist.	price>
R-C-1619	BFH772 CAS ：890128-81-1	BFH772,a structure analogue of BAW2881,is a potent and selective VEGF inhibitor.BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM.BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR,and KIT kinases,with IC50 values ranging between 30 and 160 nM.	price>
R-R-3319	(R)-Mirtazapine CAS No.61364-37-2	(R)-Mirtazapine ((R)-Org3770)/CAS No.61364-37-2 is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4.	price>
R-C-1620	HMN-214 CAS No. 173529-46-9	HMN-214 inhibits polo-like and cyclin-dependent kinase activity,has potent antimicrotubular effects and results in profound apoptosis and antitumor activity in a broad spectrum of human xenografts.	price>
R-R-3320	OPC-14523 hydrochloride CAS No.145969-31-9	OPC-14523 hydrochloride/CAS No.145969-31-9 is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity.	price>
R-C-1621	HMN-176 CAS No. 173529-10-7	HMN-176 is an active metabolite of HMN-214,which has a potent antitumor activity in mouse xenograft models.HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.	price>
R-R-3321	Clozapine-d4 CAS No.204395-52-8	Clozapine-d4/CAS No.204395-52-8 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.	price>
R-C-1622	U93631 CAS:152273-12-6	U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid,time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.	price>
R-R-3322	F 13714 fumarate CAS No.208109-39-1	F13714 fumarate/CAS No.208109-39-1, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.	price>
R-C-1624	HUHS015 CAS:1453097-13-6	HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo.The bioavailability(BA)of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells,which are human hormone-independent prostate cancer cells,in a mouse xenograft model without untoward effects.	price>
R-R-3323	CJ033466 CAS No.519148-48-2	CJ033466/CAS No.519148-48-2 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect.	price>
R-C-1623	ML141 CAS:71203-35-5	ML141(CID-2950007)is demonstrated to be a potent,selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases(Rac1,Rab2,Rab7).ML141 is associated with an increase in p38 activation and may induce p38-dependent apoptosis/senescence.ML141 also protects neuroblastoma cells from metformin-induced apoptosis.	price>
R-R-3324	(Rac)-WAY-161503 CAS No.75704-24-4	(Rac)-WAY-161503/CAS No.75704-24-4 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.	price>
R-C-1625	Sotagliflozin (LX4211) CAS：1018899-04-1	Sotagliflozin（LX4211)is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized,placebo-controlled trial.LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1(SGLT1)-mediated absorption of intestinal glucose.	price>
R-R-3325	RU 24969 succinate CAS No.107008-28-6	RU 24969 succinate/CAS No.107008-28-6 is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease.	price>

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