Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-3190	Nelotanserin CAS No.839713-36-9	Nelotanserin/CAS No.839713-36-9 is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.	price>
R-R-3191	Pumosetrag Hydrochloride CAS No.194093-42-0	Pumosetrag Hydrochloride (MKC-733; DDP-733)/CAS No.194093-42-0 is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.	price>
R-C-1492	Bicalutamide (ICI-176334) CAS：90357-06-5	Bicalutamide is a synthetic,nonsteroidal antiandrogen.Bicalutamide competitively binds to cytosolic androgen receptors in target tissues,thereby inhibiting the receptor binding of androgens.This agent does not bind to most mutated forms of androgen receptors.	price>
R-R-3192	Befiradol hydrochloride CAS No.2436760-81-3	Befiradol hydrochloride (NLX-112 hydrochloride)/CAS No.2436760-81-3 is a selective 5-HT1A receptor agonist.	price>
R-C-1493	Letrozole (CGS 20267) CAS:112809-51-5	Letrozole(CGS 20267)is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone,thyroid-stimulating hormone(TSH),luteinizing hormone(LH),follicle-stimulating hormone(FSH),or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies.Letrozole induces autophagy.	price>
R-R-3193	Xaliproden hydrochloride CAS No.90494-79-4	Xaliproden hydrochloride (SR57746A)/CAS No.90494-79-4 is a potent, selective and orally active agonist of 5-HT1A receptor, shows a high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50=3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D2 receptor, has moderate affinity (IC50=0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases.	price>
R-C-1494	Enalaprilat Dihydrate CAS: 84680-54-6	Enalaprilat is the active metabolite of enalapril.It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril.	price>
R-R-3194	GR 125743 CAS No.148547-33-5	GR 125743/CAS No.148547-33-5 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively.	price>
R-C-1495	Daptomycin CAS:103060-53-3	Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.	price>
R-R-3195	Ecopipam hydrochloride CAS No.190133-94-9	Ecopipam (SCH 39166) hydrochloride/CAS No.190133-94-9 is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity.	price>
R-C-1496	BI-78D3 CAS:883065-90-5	BI-78D3(JNK Inhibitor X),is a potent JNK inhibitor.BI-78D3 dose-dependently inhibits the phosphorylation of JNK substrates both in vitro and in cell.BI-78D3 not only blocks JNK dependent Con A-induced liver damage but also restores insulin sensitivity in mouse models of type 2 diabetes.	price>
R-R-3196	A-582941 dihydrochloride CAS No.848591-90-2	A-582941 dihydrochloride/CAS No.848591-90-2 is a potent, selective and brain-penetrant partial agonist of α7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research.	price>
R-C-1497	SKF96365 CAS:130495-35-1	SKF96365,originally identified as a blocker of receptor-mediated calcium entry, is widely used diagnostically,as a blocker of transient receptor potential canonical type(TRPC)channels.	price>
R-R-3197	LP44 hydrochloride CAS No.824958-12-5	LP44 (hydrochloride)/CAS No.824958-12-5 is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration.	price>
R-C-1498	AG-120(Ivosidenib) CAS:1448347-49-6	AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1),with potential antineoplastic activity.	price>
R-R-3198	Brilaroxazine CAS No.1239729-06-6	Brilaroxazine (RP5603)/CAS No.1239729-06-6 is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki=1.5 nM) and 5-HT2A (Ki=2.5 nM), and has antagonist activity at 5-HT2B (Ki=0.19 nM), and 5-HT7 (Ki=2.7 nM) receptors. Brilaroxazine is an atypical antipsychotic agent, and has the potential to improve cognitive impairments in neuropsychiatric and neurological diseases in vivo.	price>
R-C-1499	Nemiralisib (GSK2269557) CAS:1254036-71-9	Nemiralisib(GSK2269557 free base)is a potent and highl selective PI3Kδ inhibitor with a pKi of 9.9.	price>
R-R-3199	SB 271046 Hydrochloride CAS No.209481-24-3	SB 271046 Hydrochloride (SB 271046A)/CAS No.209481-24-3 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).	price>
R-C-1500	gsk2292767 CAS:1254036-66-2	GSK2292767 is a potent and selective inhibitor of phosphatidylinositol 3-kinase δ(PI3Kδ;Ki=79pM).GSK2292767 is>100-fold selective for PI3Kδ over a panel of 250 kinases.	price>
R-R-3200	Talipexole dihydrochloride CAS No.36085-73-1	Talipexole dihydrochloride (B-HT 920 dihydrochloride)/CAS No.36085-73-1 is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.	price>

532533534535536537 538539540541542