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Catalog	name	Description	price
R-C-1334	MSX122 CAS：897657-95-3	MSX-122 is an orally bioavailable inhibitor of CXCR4(IC50=10 nM)with potential antineoplastic and antiviral activities.CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4,preventing the binding of stromal derived factor-1 (SDF-1)to the CXCR4 receptor and receptor activation,which may result in decreased tumor cell proliferation and migration.	price>
R-R-3034	RMC-4998 CAS No.2642037-07-6	RMC-4998/CAS No.2642037-07-6 is a molecular glue compound with good antitumor activity. RMC-4998 is able to form a ternary complex with CYPA and an activated KRAS G12C mutant. Furthermore, CYPA binding to KRAS G12C blocks the interaction between activated KRAS mutants and downstream effector proteins, thereby inhibiting signaling that promotes cell proliferation.	price>
R-C-1335	XY1 CAS：1624117-53-8	XY1 is a close analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.SGC707 is a potent,selective allosteric inhibitor of PRMT3(IC50=50nM).It inhibits the methylation of histones in cells with an IC50 value below 1 µM.	price>
R-R-3035	6H05 TFA CAS No.2061344-88-3	6H05 TFA/CAS No.2061344-88-3 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).	price>
R-C-1336	PS-1145 CAS：431898-65-6	PS-1145 is a selective IκB kinase(IKK)inhibitor(IC50100 nM).PS1145 efficiently inhibited both basal and induced NF-kappaB activity in PC cells.PS1145 induced caspase 3/7-dependent apoptosis in PC cells and significantly sensitized PC cells to apoptosis induced by tumor necrosis factor alpha.PS1145 inhibited PC cell proliferation.PS1145 enhances apoptosis in DMBA-induced tumor in male Wistar rats.	price>
R-R-3036	Nexinhib20 CAS No.331949-35-0	Nexinhib20/CAS No.331949-35-0 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity.	price>
R-C-1337	FPH2(BRD9424) CAS：957485-64-2	FPH2(BRD-9424)is an inducer of proliferation of primary human hepatocytes.In vitro,FPH2 induced functional proliferation of hepatocytes and might be useful for expanding mature human primary hepatocytes.FPH2(40μM)increased the area of hepatocyte colonies with more hepatocytes and Ki67-positive nuclei,which exhibited hepatocyte nuclear morphologies.In primary human hepatocytes from six additional cell sources,FPH2 increased hepatocytes expansion.FPH2 increased hepatocyte at a rate that is consistent with liver regeneration kinetics in vivo .	price>
R-R-3037	ARS-1630 CAS No.1698055-86-5	ARS-1630/CAS No.1698055-86-5, a less active enantiomer of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1.	price>
R-C-6457	POLY(4-VINYL PYRIDINE-CO-2-HYDROXYETHYL METHACRYLATE), RANDOM	Poly(4-vinyl pyridine-co-2-hydroxyethyl methacrylate)is a random copolymer composed of 4-vinyl pyridine and 2-hydroxyethyl methacrylate units.The 4-vinyl pyridine units introduce cationic and basic properties to the copolymer,while the 2-hydroxyethyl methacrylate units contribute hydrophilic and potentially hydrogen bonding functionalities.	price>
R-C-1338	BMS833923 CAS：1059734-66-5	BMS-833923(XL-139)is an orally bioavailable small-molecule inhibitor of Smoothened with potential antineoplastic activityinhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner with an IC50 of 21 nM.	price>
R-R-3038	KRAS inhibitor-10 CAS No.2578876-75-0	KRAS inhibitor-10 (compound 11)/CAS No.2578876-75-0 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins. KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer. KRAS inhibitor-10 is a tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1.	price>
R-C-6458	POLY(VINYL ALCOHOL-CO-ACRYLIC ACID),RANDOM	Poly(vinyl alcohol-co-acrylic acid),RANDOM refers to a copolymer created from two different monomers: vinyl alcohol and acrylic acid.PVA is a synthetic polymer that is known for its water solubility,as well as its good film-forming,emulsifying,and adhesive properties.PVA is also biodegradable and non-toxic.The specific properties of the copolymer will depend on the ratio of vinyl alcohol to acrylic acid, the degree of the polymerization,and the molecular weight of the resulting polymer.	price>
R-C-1339	NU2058 CAS：161058-83-9	NU2058(O(6)-Cyclohexylmethylguanine)is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay.It also potentiates melphalan(DMF 2.3),and monohydroxymelphalan(1.7),but not temozolomide or ionising radiation.	price>
R-R-3039	KRAS G12C inhibitor 15 CAS No.2349393-21-9	KRAS G12C inhibitor 15/CAS No.2349393-21-9 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM.	price>
R-C-6459	POLY(4-[TERT-BUTOXYCARBONYLOXY]-STYRENE-CO-4-ACETOXYSTYRENE),RANDOM	Poly(4-[tert-butoxycarbonyloxy]-styrene-co-4-acetoxystyrene) is a random copolymer consisting of 4-[tert-butoxycarbonyloxy]-styrene and 4-acetoxystyrene units. This copolymer is designed to possess a combination of properties derived from both monomer units.	price>
R-C-1340	SB202190 (FHPI) CAS：152121-30-7	SB202190(FHPI)is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays,sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo.SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1.SB202190 significantly suppresses Erastin‐dependent ferroptosis.	price>
R-R-3040	APS6-45 CAS No.2188236-41-9	APS6-45/CAS No.2188236-41-9 is an orally active tumor-calibrated inhibitor (TCI). APS6-45 inhibits RAS/MAPK signaling and exhibits antitumor activity.	price>
R-C-6460	p-Nitrophenylacetonitrile CAS：555-21-5	4-Nitrophenylacetonitrile,4-Nitrophenylacetonitrile is used as a radical inhibitor in the polymerization of vinyl acetate.Our company can provide large-sized,KG grade products.	price>
R-C-1341	PHA-767491HCL CAS：942425-68-5	PHA-767491,also known as CAY10572,is a potent,ATP-competitive dual cdc7/cdk9 inhibitor(IC50 values are 10 and 34 nM respectively)that prevents initiation of DNA replication.PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.PHA-767491 in combination with 5-FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP-Ribose)polymerase fragmentation in HCC cells.	price>
R-R-3041	MRTF/SRF-IN-1 CAS No.1922098-90-5	MRTF/SRF-IN-1 (example 41)/CAS No.1922098-90-5 is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis.	price>

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