Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-2345	Tyk2-IN-8 CAS No.2704587-24-4	Tyk2-IN-8/CAS No.2704587-24-4 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease.	price>
R-C-646	GW9508 cas:885101-89-3	GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor(GPCR)GRP40/FFA1 receptor (EC50 ?50 nM)with reduced activity towards family members GRP120 (EC50?3.5 μM), GRP41/GRP43 (EC50>50 μM),as well as a panel of eight other free fatty acid (FFA) and prostaglandin receptors.	price>
R-R-2346	Filgotinib-d4 CAS No.2041095-50-3	Filgotinib-d4/CAS No.2041095-50-3 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.	price>
R-C-647	CI994 cas:112522-64-2	Tacedinaline(N-acetyldinaline)is an inhibitor of the histone deacetylase(HDAC) with IC50s of 0.9,0.9,1.2μM for recombinant HDAC 1,2 and 3 respectively.	price>
R-R-2347	LFM-A13 CAS No.62004-35-7	LFM-A13/CAS No.62004-35-7 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research.	price>
R-C-648	AT7519HCL cas:902135-91-5	AT7519 Hydrochloride is a potent inhibitor of CDKs,with IC50s of 210,47,100,13, 170,and <10 nM for CDK1,CDK2,CDK4 to CDK6,and CDK9,respectively.	price>
R-R-2348	(3R,4S)-Tofacitinib CAS No.1092578-46-5	(3R,4S)-Tofacitinib/CAS No.1092578-46-5 is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.	price>
R-C-649	StemRegenin 1 (SR1) CAS No. 1227633-49-9	StemRegenin 1(SR1)is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).	price>
R-R-2349	Fosifidancitinib CAS No.1237168-58-9	Fosifidancitinib/CAS No.1237168-58-9 is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases.	price>
R-C-650	KI8751 cas:228559-41-9	Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays.	price>
R-R-2350	Nimucitinib CAS No.2740557-24-6	Nimucitinib/CAS No.2740557-24-6 is a Janus kinase (JAK) inhibitor.	price>
R-C-651	Rociletinib (CO-1686) cas:1374640-70-6	Rociletinib(CO-1686,AVL-301)is an irreversible,mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays,respectively.	price>
R-R-2351	(Rac)-Ruxolitinib-d9 CAS No.2469553-67-9	(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9)/CAS No.2469553-67-9 is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor.	price>
R-C-652	RGFP966	RGFP966 is a highly selective HDAC3 inhibitor with an IC50 of 80 nM and shows no inhibition to other HDACs at concentrations up to 15 μM.RGFP966 can penetrate the blood brain barrier(BBB).	price>
R-R-2352	JAK-IN-25 CAS No.2127110-22-7	JAK-IN-25 (compound 19)/CAS No.2127110-22-7 is a potent JAK inhibitor with IC50s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2, JAK1, JAK2, JAK3, respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC50 of 28 nM. JAK-IN-25 has the potential for cancer research.	price>
R-C-653	AZD1080 cas:612487-72-6	AZD1080 is a novel GSK3 inhibitor,rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.	price>
R-R-2353	Lepzacitinib CAS No.2321488-47-3	Lepzacitinib/CAS No.2321488-47-3 is a Janus kinase inhibitor targeting to JAK 1/3. Lepzacitinib exhibits anti-inflammatory effect and inhibits atopic dermatitis and other skin diseases.	price>
R-C-654	tariquidar cas:206873-63-4	Tariquidar(XR9576)is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM in CHrB30 cell line,reverses drug resistance in MDR cell Lines.	price>
R-R-2354	Dehydrocrenatidine CAS No.65236-62-6	Dehydrocrenatidine/CAS No.65236-62-6, a natural alkaloid, is a specific JAK inhibitor. Dehydrocrenatidine inhibits voltage-gated sodium channels and ameliorates mechanic allodia in a rat model of neuropathic pain.	price>
R-C-655	SKLB610 cas:1125780-41-7	SKLB610 is a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo.	price>

447448449450451452 453454455456457