Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-M-710	BQ-610	BQ-610 is a very potent ET-A receptor antagonist which is about 30000 times more selective for ET-A receptors than for ET-B receptors. Furthermore, it has been found that BQ-610 strongly antagonizes ET-1 induced concentration in porcine coronary artery with a pA₂ value of 8.2.	price>
R-R-1863	Taltobulin trifluoroacetate CAS No.228266-41-9	Taltobulin trifluoroacetate (HTI-286 trifluoroacetate)/CAS No.228266-41-9, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.	price>
R-R-1864	Pladienolide B CAS No.445493-23-2	Pladienolide B/CAS No.445493-23-2 is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis.	price>
R-CG-039	PLGA-Hydrazone(Hyd)-PEG-CHO	Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-hydroxyl,PLGA-Hyd-PEG-CHO from ruixi.Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG CHO was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-712	Bradykinin (1-5) trifluoroacetate salt	The fragment RPPGF and the two dipeptides Phe-Arg and Ser-Pro are obtained by action of angiotensin-converting enzyme (ACE) on bradykinin. RPPGF inhibits thrombin-induced platelet activation, and in high concentration, the pentapeptide inhibits thrombin-induced coagulant activity.	price>
R-R-1865	Milademetan CAS No.1398568-47-2	Mliademetan (DS-3032)/CAS No.1398568-47-2 is an MDM2 inhibitor that is specific and oral for acute myeloid leukemia (AML) research.	price>
R-PL0996-10k	PLGA-thioketal(TK)-PEG-BIOTIN	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-biotin，PLGA-thioketal(TK)-PEG-BIOTIN from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-biotin this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-713	Bradykinin (1-7) acetate salt	Bradykinin (1-7) acetate salt,CAS :23815-87-4 from ruixi.It is a synthetic peptide.	price>
R-R-1866	Erasin	Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis.	price>
R-CG-040	PLGA-thioketal(TK)-PEG-Azide(N3)	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-Azide(N3) ，PLGA-thioketal(TK)-PEG-Azide(N3) from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-Azide(N3) this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-714	Lys-Bradykinin acetate salt	Lys-Bradykinin acetate salt,CAS:342-10-9 from ruixi.Kallidin is the precursor of the vasodilator bradykinin.	price>
R-R-1867	ROC-325 CAS No.1859141-26-6	ROC-325/CAS No.1859141-26-6 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis.	price>
R-CG-041	PLGA-thioketal(TK)-PEG-Alkyne	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-Alkyne,PLGA-thioketal(TK)-PEG-Alkyne from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-Alkyne this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-715	Caerulein (desulfated)	Caerulein (desulfated),CAS:20994-83-6 from ruixi.It is a synthetic peptide.	price>
R-R-1868	Bioymifi CAS No.1420071-30-2	Bioymifi (DR5 Activator)/CAS No.1420071-30-2, a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis.	price>
R-CJK20005	Mesoporous Fe3O4 nanospheres (Particle size:100nm-400nm)	Mesoporous Fe3O4 nanospheres from ruxii.Mesoporous Fe3O4 nanospheres have high magnetic saturation value and can be used as MRI contrast agents.Fe3O4 nanospheres have the advantages of high efficiency in drug loading, drug release, magnetic resonance imaging and low cytotoxicity, and have potential applications in biomedical field.	price>
R-M-716	Caerulein ammonium salt	Caerulein ammonium salt（CAS : 17650-98-5） is a more potent secretagogue than its analog CCK-8. Ceruletide is applied in the diagnosis of pancreatic function and, in high dosage, for the induction of pancreatitis in experimental animals.	price>
R-R-1869	Milademetan tosylate hydrate CAS No.2095625-97-9	Milademetan (DS-3032) tosylate hydrate/CAS No.2095625-97-9 is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.	price>
R-CG-042	PLGA-thioketal(TK)-PEG-folate(FA)	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-folate,PLGA-thioketal(TK)-PEG-folate from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-folate this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-717	Calcitonin (chicken) trifluoroacetate salt	Calcitonin (chicken) trifluoroacetate salt,CAS：100016-62-4 from ruixi.It is a synthetic peptide.	price>

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