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R-M-470 Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide is a fluorogenic substrate for neutral metalloendopeptidases.such as enkephalinase (NEP 2411),Pseudomonas aeruginosa pseudolysin,and thermolysin. price>
R-M-688 Eledoisin acetate salt Eledoisin acetate salt,cas:69-25-0 is a tachykinin isolated. price>
R-R-1841 Etalocib CAS No.161172-51-6 Etalocib (LY293111)/CAS No.161172-51-6, an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis. price>
R-CG-020 DSPE-Se-Se-PEG-BIOTIN 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-BIOTIN,DSPE-Se-Se-PEG-BIOTIN from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG BIOTIN(peg-biotin).The product(DSPE-Se-Se-PEG-BIOTIN)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-471 Abz-Ala-Phe-Ala-Phe-Asp-Val-Phe-3-nitro-Tyr-Asp-OH trifluoroacetate salt Abz-AFAFDVY(NO₂)D,a fluorogenic (FRET) substrate for endoproteinase AspN,Asp-specific proteases from Staphylococcus aureus,Bacillus licheniformis and Streptomyces griseus. price>
R-M-689 Endomorphin-1 trifluoroacetate salt Endomorphin-1 trifluoroacetate salt,CAS :189388-22-5 from ruixi.Endomorphin-1 (YPWF-amide) is the most potent and selective endogenous agonist for the mu-opiate receptor so far described .It may be a natural ligand for this receptor.Endomorphin-1 has been shown to inhibit the aggregation of Aβ in vitro and is effective in vivo. price>
R-R-1842 Ursonic acid CAS No.6246-46-4 Ursolic acid/CAS No.6246-46-4, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. price>
R-CG-021 DSPE-Se-Se-PEG-sh 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-thiol,DSPE-Se-Se-PEG-sh from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-sh).The product(DSPE-Se-Se-PEG-thiol)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-472 Abz-Ala-Phe-Arg-Phe-Ser-Gln-EDDnp trifluoroacetate salt Abz-AFRFSQ-EDDnp, best human kallikrein 6 (hK6) FRET substrate so far described. price>
R-M-690 Endomorphin-2 trifluoroacetate salt Endomorphin-2 trifluoroacetate salt ,CAS: 141801-26-5 from ruixi.Endomorphin-2 (YPFF-amide) shows, as endomorphin-1, the highest affinity and specificity for the mu-opiate receptor found so far in the mammalian nervous system. It has potent mu-selective bioactivity, including analgesia. Szegedi et al. showed that endomorphin-2 protects against Aβ 1-42 in vitro and in vivo. Acylated endomorphin-2 is used as cosmetic ingredient for sensitive skin care. price>
R-R-1843 Trametinib-13C,d3 CAS No.2712126-59-3 Trametinib-13C,d3/CAS No.2712126-59-3 is the 13C- and deuterium labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis. price>
R-CG-022 DSPE-Se-Se-PEG-N3 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-Azide,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-N3).The product(DSPE-Se-Se-PEG-N3)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-473 Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH trifluoroacetate salt Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher).The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin.The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease.Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645).FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1. price>
R-M-691 β-Endorphin (30-31) (human) β-Endorphin (30-31) (human),CAS: 7412-78-4 from ruixi.The C-terminal dipeptide Gly-Glu was shown to be an effective neurotrophic factor for the maintenance of acetylcholinesterase at both superior cervical ganglia in the denervated cat. Moreover,β-endorphin can bind to serum glycoproteins at sites for which glycyl-L-glutamic acid competes. A potential impurity of glycyl-L-glutamine used as source for L-glutamine. price>
R-R-1844 PARP14 inhibitor H10 CAS No.2084811-68-5 PARP14 inhibitor H10/CAS No.2084811-68-5, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis. price>
R-M-474 Abz-Asp-Asp-Ile-Val-Pro-Cys-Ser-Met-Ser-3-nitro-Tyr-Thr-NH₂ The internally quenched (FRET) substrate Abz-DDIVPCSMSY(NO₂)T-NH₂allows the direct, specific detection of NS3-4A protease activity . price>
R-M-692 γ-Endorphin γ-Endorphin,CAS :60893-02-9 from ruixi.It can be applied to Opioid Research. price>
R-R-1845 Eftozanermin alfa CAS No.1820660-69-2 Eftozanermin alfa (ABBV-621)/CAS No.1820660-69-2 is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies. price>
R-CG-023 DSPE-Se-Se-PEG-alkyne 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-alkyne,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-alkyne).The product(DSPE-Se-Se-PEG-alkyne)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-475 Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH,CAS:827044-38-2 Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B. price>