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Catalog	name	Description	price
R-R-1387	Angiotensin II human acetate CAS No.68521-88-0	Angiotensin II human (Angiotensin II) acetate/CAS No.68521-88-0 is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.	price>
R-ZF001	ZIF-8,50-200nm ,Zeolites and imidazoles as framework materials	Zeolitic Imidazolate Framework-8 ZIF-8 from ruixi ZIF-8,Zeolites and imidazoles as framework materials,Zeolitic Imidazolate Framework-8，ZIF-8，cas：59061-53-9 from ruixi.Zeolitic Imidazolate Framework-8 has a zeolites imidazole ester skeleton (ZIF) composed of metal ions and imidazole anion. The structure of ZIF is similar to that of silica zeolite. ZIF has high thermal stability.	price>
R-mo-254	COF-SDU1	COF-SDU1,Covalent organic framework-SDU1 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.COF-SDU1 has high crystallinity,high BET specific surface area and abundant N atom sites.Cof-sdu1 showed a large amount of CO2 absorption at 298K and 45 bar.	price>
R-R-1388	Tegaserod CAS No.145158-71-0	Tegaserod/CAS No.145158-71-0 is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research.	price>
R-PN1009	PCN-224 ,Metal organic frame material	Porphyrinic Metal-organic Framework PCN-224 PCN-224 from ruixi PCN-224 ,Metal organic frame material,Porphyrinic Metal-organic Framework PCN-224 ,PCN-224 from ruixi.A series of highly stable MOFs with 3-D nanochannels, namely PCN-224 (no metal, Ni, Co, Fe), have been assembled with six-connected Zr6 cluster and metalloporphyrins by a linker-elimination strategy.	price>
R-mo-255	COF-108	COF-108,Covalent organic framework-108 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1389	Tegaserod maleate CAS No.189188-57-6	Tegaserod maleate (SDZ-HTF-919)/CAS No.189188-57-6 is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod maleate has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research.	price>
R-mo-256	CoF2	CoF2,Cobalt(II) fluoride from ruixi.Cobalt (II) fluoride can be used in organic reaction catalyst, organic fluorination agent and preparation of cobalt trifluoride.	price>
R-R-1390	MRT199665 CAS No.1456858-57-3	MRT199665/CAS No.1456858-57-3 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370.	price>
R-MF-002	HKUST-1	HKUST-1 Metal organic frame material HKUST-1 from ruixi HKUST-1 is also known as mof-199, Cu BTC and basolite (TM) C300. HKUST-1 is a blue cubic crystal copper based microporous metal framework (MOF). It was prepared by solvothermal method. Its surface area may be close to 2200m2 / G2.	price>
R-mo-257	COF-202	COF-202,Covalent organic framework-202 from ruixi.Cof-202 has high thermal stability, low density and high porosity. The design and synthesis of cof-202 expands the type of bond and can be used to crystallize new materials with extended covalent organic frameworks.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1391	Ivaltinostat formic	Ivaltinostat (CG-200745) formic is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat formic inhibits deacetylation of histone H3 and tubulin. Ivaltinostat formic induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat formic enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU; HY-90006). Ivaltinostat formic induces apoptosis and has anti-tumour effects.	price>
R-MF177	MOF-177 Metal organic framework material	Metal-Organic Frameworks-177 MOF-177 from ruixi Metal organic framework MOF-177 is one of the most promising crystalline porous adsorbents for hydrogen adsorption.MOF-177 has very large pores and can combine the properties of polycyclic organic guest molecules.	price>
R-mo-258	COF-42	COF-42,Covalent organic framework-42 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1392	Higenamine hydrochloride CAS No.11041-94-4	Higenamine hydrochloride/CAS No.11041-94-4 is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.	price>
R-MF808	MOF-808 Metal organic framework material	Metal-Organic Frameworks-808 MOF-808 from ruixi Mof-808 has high activity of endoperoxidase. Mof-808 can be used for the colorimetric detection of hydrogen peroxide. The detection limit of hydrogen peroxide is 4.5 μ m, and the linear range is 10 μ m ~ 15 mm.	price>
R-mo-259	COF-43	COF-43,Covalent organic framework-43 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1393	PCC0208017 CAS No.2623158-64-3	PCC0208017/CAS No.2623158-64-3 is a microtubule affinity regulating kinases (MARK3/MARK4) inhibitor with IC50s of 1.8 and 2.01 nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC50s of 31.4 and 33.7 nM, respectively. PCC0208017 suppresses glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability.	price>
R-CF510	COF-5 Covalent organic framework-5	Covalent organic framework-5 COF-5 from ruixi Metal–organic frameworks (MOFs) are a class of compounds consisting of metal ions or clusters coordinated to organic ligands to form one-, two-, or three-dimensional structures. They are a subclass of coordination polymers, with the special feature that they are often porous.	price>
R-mo-260	COF-316	COF-316, Covalent organic framework-316 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>

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