Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-C-224	DLPE-PEG-NH2	At present,the company main products are synthetic phospholipids,PEG derivatives,block copolymers,gold nanoparticles,magnetic nanoparticles, mesoporous silica,reactive fluorescent dyes,fluorescent quantum dots,click chemistry and macrocyclic ligands, etc.	price>
R-R-1222	PI-103 Hydrochloride CAS No.371935-79-4	PI-103 Hydrochloride/CAS No.371935-79-4 is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.	price>
R-PN-008	6-arm-PLGA-NH2	6 arm-Poly(D,L-lactide-co-glycolide)-amine,6-arm-PLGA-NH2 from ruixi.Amine capped 6-arm poly(lactide-co-glycolide) (6-arm PLGA Amine, 6-arm PLGA-NH2) is a multiarm PLGA derivative with amine groups at each terminal of the four arms connected to one pentaerythritol core. The reactive primary amine or NH2 group can rapidly react with activated carboxyl acid such as NHS ester to form stable amide bonds. 6-arm PLGA is terminated with hydroxyl group for further modification.	price>
R-C-225	DLPE-PEG-COOH	The products are mainly used in the modification of protein drugs,peptides, liposomes,small organic molecules,PEG and ligand factors.	price>
R-R-1223	BGT226 maleate CAS No.1245537-68-1	BGT226 (NVP-BGT226 maleate)/CAS No.1245537-68-1 is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ) /mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells.	price>
R-PN-009	6-arm-PLGA-MAL	6 arm-Poly(D,L-lactide-co-glycolide)-Maleimide,6-arm-PLGA-MAL from ruixi.Maleimide capped 6-arm poly(lactide-co-glycolide) (6-arm PLGA-Maleimide, 6-arm PLGA-Mal) is a multiarm PLGA derivative with amine groups at each terminal of the four arms connected to one pentaerythritol core. The maleimide group selectively reacts with free thiol, SH, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond. 4-Arm PEG-MAL can be used for site specific protein and peptide modification.	price>
R-C-226	DSPE-Cyclodextrin	Cyclodextrin (CD) is a general term for a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase (CGT) produced by Bacillus.It usually contains 6-12 D-glucopyranosyl units.Because the glycosidic bond connecting the glucose unit cannot rotate freely,cyclodextrin is not a cylindrical molecule,but a slightly conical ring.	price>
R-R-1224	hSMG-1 inhibitor 11e CAS No.1402452-10-1	hSMG-1 inhibitor 11e/CAS No.1402452-10-1 is a potent and selective hSMG-1 kinase inhibitor with an IC50 of <0.05 nM. hSMG-1 inhibitor 11e shows >900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM).	price>
R-PN-0010	6-arm-PLGA-SH	6 arm-Poly(D,L-lactide-co-glycolide)-thiol,6-arm-PLGA-SH from ruixi.6-arm poly(lactide-co-glycolide) (4-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification.	price>
R-C-227	DSPE-PEG-HMME	Compared with HPD,a mixed porphyrin preparation for clinical application,HMME has the advantages of high photosensitivity,high selective uptake rate of tumor, strong photodynamic effect,low toxicity,no mutagenicity and teratogenicity,etc. it is an ideal new drug for photodynamic cancer treatment.	price>
R-R-1225	Sonolisib CAS No.502632-66-8	Sonolisib (PX-866)/CAS No.502632-66-8, an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity.	price>
R-PN-0011	6-arm-PLGA-NHS	6 arm-Poly(D,L-lactide-co-glycolide)-N-Hydroxysuccinimide,6-arm-PLGA-NHS from ruixi.6 arm-Poly(D,L-lactide-co-glycolide)(6-arm-PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification.	price>
R-C-228	DSPE-PEG-Casein	Casein is a phosphorus protein in animal milk.The structure formula is nh2rcooh, odorless,odorless white to yellow powder with relative density of 1.25-1.31.It is almost insoluble in water,alcohol and ether.It is soluble in dilute alkali solution,alkaline carbonate solution and concentrated acid,and precipitated in weak acid.It is hygroscopic,stable when dry,and harden rapidly when wet.Mainly used as food additives,casein gum,cosmetics,safety matches,pigments,etc.	price>
R-R-1226	Vps34-PIK-III CAS No.1383716-40-2	Vps34-PIK-III/CAS No.1383716-40-2 is an orally active and selective VPS34 inhibitor (IC50=18 nM). Vps34-PIK-III effectively inhibits autophagy and can be used as a molecular tool. vps34-PIK-III is also a PI3K inhibitor that inhibits the expression of genes in liver cancer stem cells (CSCs).	price>
R-PN-0012	6-arm-PLGA-Folate	6 arm-Poly(D,L-lactide-co-glycolide)-Folic acid,6-arm-PLGA-Folate,6-arm-PLGA-FA from ruixi.6-arm poly(lactide-co-glycolide) (6-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification.	price>
R-C-229	DSPE-PEG-Catalase	Poly(z-diol) increases solubility and stability.Long circulating liposomes (LCL) were prepared by modifying the surface of liposomes with polyethylene glycol (PEG),which could prolong the half-life of liposomes,improve its stability in blood circulation,change the biological distribution of liposomes,and have targeting property.Silica modified PEG can modify silicon,glass and other materials,which has good biocompatibility.	price>
R-R-1227	PI4KIIIbeta-IN-10 CAS No.1881233-39-1	PI4KIIIbeta-IN-10/CAS No.1881233-39-1 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM.	price>
R-PN-0013	8-arm-PCL	8 arm-poly(ε-caprolactone),8-arm-PCL from ruixi.8 arm poly (ε - caprolactone) (8-arm PCL).The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.The end group is OH.	price>
R-C-230	DSPE-PEG-Heparin	Heparin sodium salt is a highly sulfated glycosaminoglycan,which is widely used as an injectable anticoagulant.The heparin cascade is widely used as an anticoagulant to accelerate the coagulation rate of heparin.Heparin is used as an anticoagulant,mainly through its enhanced at-III mediated inhibition of coagulation factors,including thrombin and factor Xa interaction with at-iii.	price>
R-R-1228	Ginsenoside Rk1 CAS No.494753-69-4	Ginsenoside Rk1/CAS No.494753-69-4 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis. Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway.	price>

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