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R-R-1138 CHPG CAS No.170846-74-9 CHPG/CAS No.170846-74-9 is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways. price>
R-PL-0100 PCL-PEG-LA poly(ε-caprolactone)-polyethylene glycol--Lipoic acid,PCL-PEG-LA from ruixi poly(ε-caprolactone)-polyethylene glycol--Lipoic acid (PCL-PEG-LA ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-SZ-0003 UCNPS-PEG Compared with traditional fluorescent materials,upconversion fluorescent nanoparticles have the following advantages:1) near-infrared light as excitation light source,1) improve its penetration ability in biological tissues;2) reduce the damage of light source to biological samples;3) as the absorption of light in vivo is mainly concentrated in the ultraviolet visible region,so it is less interfered by autofluorescence.These advantages make upconversion fluorescent materials widely used in molecular detection and imaging in vivo. price>
R-DS-0045 DSPE-PEG3400-RGERPPR DSPE conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides. price>
R-R-1139 AKT-IN-6 CAS No.1430056-54-4 AKT-IN-6 (Example 13)/CAS No.1430056-54-4 is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1). price>
R-PL-0101 PCL-PEG-Tosyl poly(ε-caprolactone)-polyethylene glycol--Tosylate PCL-PEG-Tosyl from ruixi poly(ε-caprolactone)-polyethylene glycol--Tosylate (PCL-PEG-Tosyl ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-SZ-0004 UCNPS-SiO2 The size of nanoparticles and the thickness of silica coating can be customized according to customer needs.The surface coated silica layer makes the nanoparticles have good hydrophilicity and can be directly dispersed in water. The size of nanoparticles can be customized according to customer needs.The product has uniform particle size,high luminous quantum efficiency and good light stability.After surface modification,this series of products can be used for fluorescence imaging, biological detection,photodynamic therapy,and remote release of anticancer drugs and biomolecules. price>
R-DS-0046 DSPE-PEG-c(RGDyK) The immunogenicity of C (rgdyk)-peg-dspe was derived from C (rgdyk)-peg-dspe, which eventually led to serious life-threatening toxicity.However,C(rgdyk) itself had no ability to induce immune response.The results of antibody typing showed that IgG3 was the main subtype of specific IgG antibody of C (rgdyk) modified liposomes,and the antibody production rate was fast,suggesting that C (rgdyk) modified liposomes belonged to T cell independent type-2 (TI-2) antigen. At the same time,it was found that cytotoxic chemotherapeutic drugs could mask the immunogenicity of C (rgdyk) modified liposomes,but there might be safety problems when they were used to deliver molecular targeted drugs with good tumor cell specificity and low adverse reactions in normal tissues. price>
R-R-1140 Phellopterin CAS No.2543-94-4 Phellopterin/CAS No.2543-94-4 is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium. price>
R-PL-0102 PCL-PEG-Acetylthio poly(ε-caprolactone)-polyethylene glycol--Acetylthio,PCL-PEG-Acetylthio from ruixi poly(ε-caprolactone)-polyethylene glycol--Acetylthio(PCL-PEG-Acetylthio ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-SZ-0005 UCNPS-OA The emission wavelengths of oil soluble rare earth doped upconversion fluorescent nanoparticles are red,green and blue,and the particle diameter is 30-60nm. Ruixi can provide such products in the morning. price>
R-DS-0047 DSPE-PEG-iNGR(CRNGRGPDC) LPNs were prepared with poly (histidine)(PHIS) as the core and di stearyl phosphatidylethanolamine polyethylene glycol (DSPE-PEG) and lecithin (EPC) as the single-layer shell.The anti-tumor drug DOX was encapsulated in LPNs and modified with the peptide ingr (crngrgpdc). price>
R-R-1141 Crosstide CAS No.171783-05-4 Crosstide/CAS No.171783-05-4 is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt. price>
R-PL-0103 PCL-PEG-Aminooxy poly(ε-caprolactone)-polyethylene glycol--Aminooxy,PCL-PEG-Aminooxy from ruixi poly(ε-caprolactone)-polyethylene glycol--Aminooxy (PCL-PEG-Aminooxy) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-AS-0005 UCNPS-PAA Upconversion nanomaterial is a kind of fluorescent nano material,which is excited by low-energy infrared or near-infrared light by doping rare-earth ions, and radiates high-energy visible light.Rare earth doped NaYF4:Yb-ER,Gd upconversion fluorescent nanomaterials are one of the most effective near infrared visible conversion materials known,and have great potential in biological analysis chemistry and biological imaging. price>
R-DS-0048 DSPE-PEG-NGR(ASP-Gly-Arg)-CD13 Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Polyethylene glycol phosphowax can significantly improve the blood circulation time and stabilize the drug package. These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides.The targeting peptide can target CD13 receptor which is over expressed in tumor neovascularization epithelial cells. price>
R-R-1142 CCT365623 hydrochloride CAS No.2126136-98-7 CCT365623 hydrochloride/CAS No.2126136-98-7 is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties. price>
R-PL-0104 PCL-PEG-NPC poly(ε-caprolactone)-polyethylene glycol--Nitrophenyl Carbonates PCL-PEG-NPC from ruixi poly(ε-caprolactone)-polyethylene glycol--Nitrophenyl Carbonates (PCL-PEG-NPC) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-I-009 ptbua-p4vp Tert butyl acrylate(tert butyl acrylate)is an important organic ester.It is a colorless and transparent liquid at room temperature.It has good chemical and physical properties such as weather resistance,water resistance,oil resistance and chemical resistance.Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin. price>
R-DS-0049 DSPE-PEG-FAL Non lysosomal cationic liposomes modify common cationic liposomes by introducing special fal peptides.Firstly,the product dspe-pec-fal was obtained by modifying dspe-peg-nh2 with fl polypeptide.The results of NMR and IR showed that the Al peptide was successfully connected to dspe-pec.Cationic lipid 2-dioleoylhydropropyl-3-n,N,k-trimethylammonium (DOTAP) was selected as cationic lipid,Liposomes modified by fal were prepared by film dispersion method using neutral auxiliary lipid dioleoyl phosphatidylethanolamine (DOPE) and the mixture of DSPE-PEC-NH2 and DSPE-PEG-FAL. price>