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Catalog	name	Description	price
R-PL-0119	PAA-PEG-NH2	Polyacrylic acid-polyethylene glycol-Amine,PAA-PEG-NH2 from ruixi Polyacrylic acid-polyethylene glycol-Amine (PAA-PEG-NH2 ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0064	c(RGDDYK)-PEG3400-DSPE	c(RGDDYK) is a model peptide targeting molecule,which can be modified on the surface of liposomes.The immunogenicity and related mechanism of peptide mediated targeting nanoparticles were systematically studied.After intravenous injection of c(RGDDYK) modified liposomes,a large number of antibodies were produced. Repeated injections resulted in the deposition of immune complexes with antibodies in liver,kidney and lung tissues,activating the complement system, releasing allergens and cytokines,resulting in hypersensitivity such as capillary leakage,alveolar protein deposition,inflammatory cell infiltration,kidney and liver congestion,resulting in hypothermia or death in mice.	price>
R-R-1158	Pachymic acid CAS No.29070-92-6	Pachymic acid/CAS No.29070-92-6 is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.	price>
R-PL-0120	PAA-PEG-COOH	Polyacrylic acid-polyethylene glycol-carboxyl,PAA-PEG-COOH from ruixi Polyacrylic acid-polyethylene glycol-carboxyl(PAA-PEG-COOH) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-FA-001	FA-PEG-Glycyrrhetinic acid	Folic acid is a kind of water-soluble vitamin,which is named after the rich content of green leaves,also known as pteroylglutamic acid.Glycyrrhetinic acid has the anti-inflammatory effect of butazone or hydrocortisone.	price>
R-DS-0065	LyP-1-PEG3400-DSPE	Cyclopeptide LyP-1 modified liposomes:polypeptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs. It has also been proved by experiments that it can enhance the targeting specificity of drugs,enhance the targeted absorption of drugs,improve the anti-tumor effect,and at the same time,it can improve the original insoluble properties of some small molecule drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-R-1159	Vevorisertib trihydrochloride CAS No.1416775-08-0	Vevorisertib (ARQ 751) trihydrochloride/CAS No.1416775-08-0 is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT. Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively. Vevorisertib trihydrochloride can be used for the research of cancer.	price>
R-PL-0121	PAA-PEG-MAL	Polyacrylic acid-polyethylene glycol-Maleimide,PAA-PEG-MAL from ruixi Polyacrylic acid-polyethylene glycol-Maleimide(PLLA-PEG-MAL) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
R-N-001	Acrylates-PEG-N3	Azide can cyclize with terminal alkyne in the presence of copper catalyst. Acrylates can generate hydrogels.Polyethylene glycol can increase the solubility and stability of drugs,reduce the immunogenicity of peptides and proteins,and inhibit the nonspecific binding of charged molecules on the modified surface.It can modify proteins,peptides and other small molecular materials.It is widely used in pharmaceutical research,drug release,new nano materials research and cell culture.	price>
R-DS-0066	c(RGDyK)-pHA-PEG-DSPE	Peptide mediated targeting drug nanopreparation is an active targeting drug preparation which introduces peptide targeting molecules onto the surface of nano carriers.It can increase the amount of drugs reaching tumor tissue and tumor cells,and achieve the goal of effective treatment of tumor.c(RGDyK) was used as a model peptide targeting molecule,which could be modified on the surface of liposomes.The immunogenicity and related mechanism of peptide mediated targeting nanoparticles were systematically studied.	price>
R-R-1160	Deferoxamine CAS No.70-51-9	Deferoxamine (Deferoxamine B)/CAS No.70-51-9 is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19.	price>
R-PL-0122	PAA-PEG-NHS	Polyacrylic acid-polyethylene glycol-N-Hydroxysuccinimide,PAA-PEG-NHS from ruixi Polyacrylic acid-polyethylene glycol-N-Hydroxysuccinimide(PLLA-PEG-NHS ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
R-1050-20k	NHS-PEG-CHO	The active ester reacts with primary amine group at ph7-8.5 to form stable amide bond.Polyethylene glycol can increase the solubility and stability of drugs, reduce the immunogenicity of peptides and proteins,and inhibit the nonspecific binding of charged molecules on the modified surface.It can modify proteins, peptides and other small molecular materials.It is widely used in pharmaceutical research,drug release,new nano materials research and cell culture.	price>
R-DS-0067	MC-DA7R-PEG-DSPE	MC-DA7R-PEG-DSPE liposome delivery system can transport BBB and BBTB, target glioma cells,stem cells and tumor neovascularization.After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1161	AS1949490 CAS No.1203680-76-5	AS1949490/CAS No.1203680-76-5 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes.	price>
R-PL-0123	PAA-PEG-Alkyne	Polyacrylic acid-polyethylene glycol-Alkyne,PAA-PEG-Alkyne from ruixi Polyacrylic acid-polyethylene glycol-Alkyne(PLLA-PEG-Alkyne ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
QY-C-1101	9,10-anthracene dicarboxylic acid	Ruixi Biotechnology Co.,Ltd.is a well-known biotechnology company in China.At present,its products mainly include synthetic phospholipids,PEG derivatives, block copolymers,gold nanoparticles,magnetic nanoparticles,mesoporous silica, reactive fluorescent dyes,fluorescent quantum dots,dot chemistry and macrocyclic ligands,etc.	price>
R-DS-0068	MC-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1162	PI3K-IN-46 CAS No.304645-61-2	PI3K-IN-46 (Intermediate 4)/CAS No.304645-61-2 is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases.	price>
R-PL-0124	PAA-PEG-SH	Polyacrylic acid-polyethylene glycol-Thiol,PAA-PEG-SH from ruixi Polyacrylic acid-polyethylene glycol-Thiol (PLLA-PEG-Thiol ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>

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