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R-R-1115 MKC-1 CAS No.125313-92-0 MKC-1 (Ro-31-7453)/CAS No.125313-92-0 is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family. price>
R-PL-0080 COOH-PtBA-COOH Poly(tert-butyl acrylate), α,ω-bis(carboxy)-terminated COOH-PtBA-COOH COOH-PtBA-COOH from ruixi Triblock copolymer COOH-PtBA-COOH .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DP-097 DSPE-PEG-GRGDS Glycine arginine glycine aspartic acid serine(grgds)is a pentapeptide containing RGD sequence.It plays an important role in monitoring angiogenesis around tumor tissue and can be used in the design of targeted delivery system of anticancer drugs.Grgds modified liposomes can be used as a carrier of anticancer drugs to target tumor cells,which provides a new idea for tumor targeted therapy. price>
R-R-1116 Arnicolide D CAS No.34532-68-8 Arnicolide D/CAS No.34532-68-8 is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. price>
R-PL-0081 PtBA-SH Poly(tert-butyl acrylate), (α-thiol, ω-bromo)-terminated PtBA-SH SH-PtBA from ruixi Amphiphilic block copolymer PtBA-SH.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-D-002-2k DSPE-PEG-DSPE Phospholipid peg is an excellent material for preparing liposomes.Modification of proteins,peptides and other small molecular materials.It is widely used in drug release,nano material research and cell culture. price>
R-R-1117 AKT-IN-3 CAS No.2374740-21-1 AKT-IN-3 (compound E22)/CAS No.2374740-21-1 is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells. price>
R-PL-0082 PtBMA-NH2 Poly(tert-butyl methacrylate), α-amino-terminated PtBMA-NH2 NH2-PtBMA from ruixi Amphiphilic block copolymer PtBMA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid price>
R-DP-096 DSPE-PEG-iRGD DSPE peg irgd is provided by Ruixi. Irgd peptide (cyclo (crgdkgpdc)) is a cyclic peptide composed of nine amino acids.It first binds to AV integrins,and then enzymolysis produces crgdk/R,which interacts with neuropilin-1,thus promoting the tissue penetration of drugs and targeting tumor and tumor infiltration. price>
R-R-1118 SY-LB-35 CAS No.2603461-70-5 SY-LB-35/CAS No.2603461-70-5 is a potent bone morphogenetic protein (BMP) receptor agonist. SY-LB-35 can stimulate significant increases in cell number and cell viability in the C2C12 myoblast cell line, and causes shifts towards the S and G2/M phases of the cell cycle. SY-LB-35 stimulates canonical Smad and non-canonical PI3K/Akt, ERK, p38 and JNK intracellular signaling pathways. price>
R-PL-0084 PMMA-NH2 Poly(methyl methacrylate), α-amino-terminated PMMA-NH2 NH2-PMMA from ruixi Amphiphilic block copolymer PMMA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-S-678 4-arm-PLA-PEO PEO is a white water-soluble thermoplastic material.PEO with relative molecular weight of 10^5~10^7 has highly ordered structure and is in crystalline state.When the temperature is higher than the melting point of the resin,the high molecular weight PEO becomes a thermoplastic material. price>
R-R-1119 ALM301 CAS No.1313439-71-2 ALM301/CAS No.1313439-71-2 is an orally active highly specific AKT inhibitor with IC50 values of 0.13 µM, 0.09 µM and 2.75 µM for AKT1, AKT2 and AKT3, respectively. ALM301 inhibits AKT phosphorylation and modulates downstream signalling in vitro. ALM301 can inhibit cancer cell proliferation and tumor growth. price>
R-BOC-0014 P4VP-b-PNIPAM Poly(4-vinylpyridine)-block-poly(N-isopropylacrylamide) P4VP-b-PNIPAM PNIPAM-b-P4VP Amphiphilic block copolymer P4VP-b-PNIPAM.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid price>
R-T-35 8-arm-PMMA-PS The core-shell structure of amphiphilic block copolymer micelles is formed by the dissolution of amphiphilic block copolymers in water.The micelles are mainly composed of hydrophilic shell and lipophilic core.Most of the materials are hydrophilic hydrophobic block copolymers,and most of the hydrophilic blocks are biocompatible copolymers. price>
R-R-1120 3,4,5-Tricaffeoylquinic acid CAS No.86632-03-3 3,4,5-Tricaffeoylquinic acid/CAS No.86632-03-3 (3,4,5-triCQA) inhibits tumor necrosis factor-α-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways. 3,4,5-Tricaffeoylquinic acid induces cell cycle arrest at G0/G1, actin cytoskeleton organization, chromatin remodeling, neuronal differentiation, and bone morphogenetic protein signaling in human neural stem cells. 3,4,5-Tricaffeoylquinic acid has the potential for the research of aging-associated diseases. price>
R-PL-0085 P2VP-b-PNIPAM Poly(2-vinylpyridine)-block-poly(N-isopropylacrylamide) P2VP-b-PNIPAM PNIPAM-b-P2VP from ruixi Amphiphilic block copolymer P2VP-b-PNIPAM.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-Y-980 PAA-G-PEO PAA is a colorless or yellowish liquid.It can form stable compounds with metal ions,calcium and magnesium,and has excellent decomposition effect on calcium carbonate and calcium hydroxide in water.Polyethylene oxide (PEO),also known as polyethylene oxide (PEO),is a crystalline,thermoplastic water-soluble polymer. price>
R-R-1121 H-Ile-Lys-Val-Ala-Val-OH H-Ile-Lys-Val-Ala-Val-OH/CAS No.131167-89-0 is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways. price>
R-BOC-0016 PNIPAm-Thiol poly(N-isopropylacrylamide)-Thiol PNIPAm-Thiol Thiol-PNIPAm from ruixi Amphiphilic block copolymer PtBA-b-PNIPAM.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>